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Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy.

11 Jun 2021

Nanobodies from nanomice and llamas show potent neutralizing activity against SARS-CoV-2 variants

While several COVID-19 vaccines have been approved to date, the constant evolution of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) receptor-binding domain (RBD) has challenged the efficacy of these vaccines.

11 Jun 2021

Special dipping solution can significantly extend the shelf life of “side streams”

When herring are filleted, more than half their weight becomes a low-value 'side stream' that never reaches our plates - despite being rich in protein and healthy omega-3 fatty acids.

11 Jun 2021

Scientists develop new method for single-cell lineage tracing of metastatic cancer

It's often cancer's spread, not the original tumor, that poses the disease's most deadly risk.

10 Jun 2021

Major anti-cancer protein released by neutrophils selectively kills tumor cells

A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells.

10 Jun 2021

New cloud technologies expand brain sciences

People often think about human behavior in terms of what is happening in the present--reading a newspaper, driving a car, or catching a football. But other dimensions of behavior extend over weeks, months, and years.

10 Jun 2021

Innovative protocol that processes saliva samples before testing may improve COVID-19 detection

The collection of nasopharyngeal swab (NPS) samples for COVID-19 diagnostic testing poses challenges including exposure risk to healthcare workers and supply chain constraints. Saliva samples are easier to collect but can be mixed with mucus or blood, and some studies have found they produce less accurate results.

10 Jun 2021

Age influences the extent to which smoking and other risk factors increase risk of depression

People who smoke, suffer from high blood pressure, obesity, or diabetes are not only at greater risk of suffering a stroke, heart attack, or dementia.

10 Jun 2021

ACTG launches phase 1 HIV cure study evaluating two promising therapies

The AIDS Clinical Trials Group, the largest global HIV research network, today announced the launch of A5386, a phase 1 HIV cure study evaluating two promising therapies.

10 Jun 2021

CWRU researcher receives $1.2 million to identify biomarkers for improving MS diagnoses

Case Western Reserve University researcher Farren Briggs was awarded $1.2 million over three years from the National Institute of Neurological Disorders and Stroke at the National Institutes of Health to identify biomarkers to improve the diagnoses of multiple sclerosis, including the ability to monitor disease activity and progression.

10 Jun 2021

Systemic biomarkers show beneficial effects of aerobic exercise on brain function in older adults

Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of Alzheimer's disease (AD). In aging humans, aerobic exercise training increases gray and white matter volume, enhances blood flow, and improves memory function.

10 Jun 2021

Can a subscription model fix primary care in the US?

In April, San Francisco-based primary care company One Medical revealed an eye-popping compensation package for its chief executive and chairman, Amir Dan Rubin. His $199 million payday, particularly noteworthy at a company that has yet to turn a profit, made Rubin the second-highest-paid CEO in the United States last year — but only on paper.

10 Jun 2021

New data underscores the benefits of 360 smart bed platform at SLEEP 2021 annual meeting

Today, Sleep Number Corporation, a leader in sleep health, innovation, science and research, presented data as posters from two new studies using its 360® smart bed at SLEEP 2021, the 35th annual meeting of the Associated Professional Sleep Societies, LLC from June 10 to 13.

10 Jun 2021

New device can provide improved protection to newborns on ventilators

If a newborn is moved or becomes agitated while on a ventilator, the breathing tube also could move. Just a few seconds with the tube in the wrong position might lead to a critical lack of oxygen to the brain, possibly resulting in lifelong disability or brain damage or even ending the baby's life.

10 Jun 2021

Deep neural network model can accurately predict the brain age of healthy patients

A study shows that a deep neural network model can accurately predict the brain age of healthy patients based on electroencephalogram data recorded during an overnight sleep study, and EEG-predicted brain age indices display unique characteristics within populations with different diseases.

10 Jun 2021

Free virtual event highlights new inventions on point-of-care medical technologies

Life sciences entrepreneurs, researchers and investors working to shape the future of point-of-care medical technologies will gather next week for a free virtual event that will highlight new inventions and connect participants to resources to advance their work.

10 Jun 2021

Efforts to prevent smoking, obesity could delay the need for angioplasty and stenting

Smokers needed their blocked arteries fixed nearly a decade earlier than non-smokers, and patients with obesity underwent these procedures four years earlier than non-obese patients, according to a new statewide study.

9 Jun 2021

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Placing medications as close as possible to the site of the disease: This sounds completely believable in theory, but is unfortunately not so simple in practice. While this works well for many drugs via the bloodstream or the digestive tract, it does not apply to the brain.

9 Jun 2021

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

A research collaboration based in Kumamoto University, Japan has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD).

9 Jun 2021

New cell-penetrating peptide may protect against life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

9 Jun 2021

Blood News and Research

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

Nanobodies from nanomice and llamas show potent neutralizing activity against SARS-CoV-2 variants

Special dipping solution can significantly extend the shelf life of “side streams”

Scientists develop new method for single-cell lineage tracing of metastatic cancer

Major anti-cancer protein released by neutrophils selectively kills tumor cells

New cloud technologies expand brain sciences

Innovative protocol that processes saliva samples before testing may improve COVID-19 detection

Age influences the extent to which smoking and other risk factors increase risk of depression

ACTG launches phase 1 HIV cure study evaluating two promising therapies

CWRU researcher receives $1.2 million to identify biomarkers for improving MS diagnoses

Systemic biomarkers show beneficial effects of aerobic exercise on brain function in older adults

Can a subscription model fix primary care in the US?

New data underscores the benefits of 360 smart bed platform at SLEEP 2021 annual meeting

New device can provide improved protection to newborns on ventilators

Deep neural network model can accurately predict the brain age of healthy patients

Free virtual event highlights new inventions on point-of-care medical technologies

Efforts to prevent smoking, obesity could delay the need for angioplasty and stenting

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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