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Study finds SARS-CoV-2 infection of endothelial cells unlikely

Researchers from the University of Queensland have investigated whether infection of endothelial cells with SARS-CoV-2 is possible.

8 Nov 2021

Identification of a candidate effector gene at COVID-19 risk locus

A new study focuses on developing a comprehensive platform to decode the effects of sequence variation identified by GWAS.

8 Nov 2021

Researchers explain why decaying SARS-CoV-2 antibodies in blood are not a problem after vaccination

A new study published in the preprint bioRxiv* server suggests vaccination helps to inflate the number of somatic hypermutations acquired by B cells. The increase in somatic hypermutations allows for an accumulation of highly matured bone marrow plasma cells.

8 Nov 2021

Pacific oyster shows antiviral activity against human coronavirus HCoV-229E

Not only are Pacific oysters (Crassostrea gigas) a seafood delicacy, but they may also be key for helping scientists figure out how to stop the spread of coronaviruses.

7 Nov 2021

Rapid antibody response induced by mRNA COVID vaccines in mice

A new study posted in the bioRxiv* preprint server used mouse models to investigate how mRNA vaccines elicit a rapid antibody response. Their findings show two different mRNA vaccines successfully boost antibody levels — IL-5, IL-6, and MCP-1 —5 days after administration.

7 Nov 2021

Pacific oyster as a weapon against SARS-CoV-2

According to an article published in the journal Reviews in Medical Virology, the effectiveness of mollusc-derived antiviral agents has been proven in many different laboratory and animal studies, while its efficacy against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has also been proposed by recent in silico studies.

7 Nov 2021

The importance of exercise for those with diabetes in the COVID era

A review aims to evaluate the effectiveness of physical activity in people with type 2 diabetes and COVID-19.

7 Nov 2021

Fast evolution of SARS-CoV-2 driven by extensive RNA deamination by host cells

A new study proposed that the RNA structure and the genome component may serve as an important basis of different deamination spectrums in SARS-CoV-2.

7 Nov 2021

New CDC report discusses efficacy of mRNA COVID vaccines in immunocompromised

The U.S. CDC reports the observed efficacy among the immunocompromised population following vaccination with mRNA vaccines against SARS-CoV-2.

7 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

SARS-CoV-2 infection amplifies immune system–related differences in dialysis, kidney transplant patients

People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from COVID-19.

7 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

Deletion of ABI3 gene in the brain may increase risk of developing Alzheimer’s disease

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them.

7 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which travel from the bone marrow.

6 Nov 2021

Washington University School of Medicine receives $17 million to address disparities in cancers

Washington University School of Medicine in St. Louis has received a $17 million grant from the National Institutes of Health to address disparities in cancer research, treatment and outcomes in underrepresented populations.

6 Nov 2021

Study identifies RNA molecule that suppresses prostate tumors

Many patients with prostate cancer are treated with drugs that lower or block hormones that fuel tumor growth. While the drugs are effective for a time, most patients eventually develop resistance to these therapies.

6 Nov 2021

Study opens a window for new therapeutic approaches to ovarian cancer

A Ludwig Cancer Research study has uncovered a cellular interaction that is essential to the ability of the immune system's cytotoxic T lymphocytes to destroy ovarian tumors and shown that its engagement could help determine the efficacy of checkpoint blockade immunotherapy in a variety of cancers.

6 Nov 2021

Key link between chronic stress and cancer discovered

Stress can have a significant negative effect on health, but our understanding of how stress impacts the development and progression of cancer is just beginning.

6 Nov 2021