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SARS-CoV-2 variants partially escape humoral immunity, but not T cells responses, study finds

Researchers at the Department of Viroscience, Erasmus MC, National Institute for Public Health and the Environment, Amsterdam UMC, and the Weill Medical College of Cornell University studied humoral and cellular immune responses to the wild type SARS-CoV-2, the B.1.1.7 variant (U.K. variant) and the B.1.351 variant (South African variant) in health care workers vaccinated with the BNT162b2 (Pfizer-BioNTech) mRNA vaccine.

31 May 2021

Novel protein interactions with ACE2 disrupted by SARS-CoV-2, contributes to COVID-19 pathologies

A severe and often fatal immune response called a “cytokine storm” can occur following SARS-CoV-2 infection. Some patients suffer from a range of complications several months after testing negative for SARS-CoV-2, and this is called ‘Long Haul’ or ‘Long’ COVID-19. The causes behind this phenomenon are not well understood.

31 May 2021

Neuropathology of COVID-19 patients caused by infection of brain pericytes

Recently, researchers from the UK and Sweden used highly sensitive multiplexed immunohistochemistry to study the brain tissue of COVID-19 patients and controls to analyze ACE2 expression in brain pericytes of patients with neurological symptoms. They also used spatial immunophenotyping to assess inflammation in brain tissue of COVID-19 patients.

31 May 2021

Study could help identify risk of secondary leukaemia in certain children

Scientists from the Wellcome Sanger Institute and the University of Cambridge found that in children with neuroblastoma - a cancer of immature nerve cells - treatment with platinum chemotherapy caused changes to the genome that could then cause leukaemia in some children later on.

31 May 2021

New study may help improve stem cell transplantation, lead to better drugs

Your immune system is always busy fighting incoming threats. It consists of a system of cells, and when there is a shortage of cells, it affects the performance of the immune system.

29 May 2021

Kinase inhibitors could provide an effective way to treat high-risk leukaemia

Australian scientists have found what could prove to be a new and effective way to treat a particularly aggressive blood cancer in children.

29 May 2021

New system can measure propofol concentration in patient's blood during surgery

Anesthesia may be an exact science, but it's not yet fully personalized. Anesthesiologists use a variety of methods to calculate the right dose for a given patient: clinical studies, medical databases and laboratory measurements, for example. However, every individual responds to anesthetics in a different way, and there's no way of knowing what that response will be until the anesthetic is administered.

29 May 2021

Blood oxygen levels may explain why memory loss is an early symptom of Alzheimer's disease

In a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for why the area, commonly referred to as 'the brain's memory center', is vulnerable to damage and degeneration, a precursor to Alzheimer's disease.

29 May 2021

Heart Failure 2021 to showcase latest evidence on prevention, management of heart failure

The latest evidence on the prevention and management of heart failure will be showcased at Heart Failure 2021, an online scientific congress of the European Society of Cardiology (ESC).

29 May 2021

AMA announces e-learning modules to standardize blood pressure measurement training across U.S. medical schools

The American Medical Association (AMA) today announced a new effort aimed at ensuring future physicians and health care professionals in the U.S. are uniformly trained on how to consistently take accurate blood pressure (BP) measurements.

29 May 2021

Mass screening reveals significantly higher numbers of coeliac disease cases in children

Mass screening of school age children has led to significantly higher numbers of coeliac disease cases being diagnosed, according to a new study presented today at the 6th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition.

29 May 2021

Loss of gut epithelial barrier responsible for COVID-19-related MIS-C in children, suggests study

A new paper in the Journal of Clinical Investigation reports that this condition is due to damage to the gut, mediated by a decrease in the protein called zonulin, which is responsible for the integrity of the gut epithelial barrier. Reduced zonulin levels are found in several inflammatory and autoimmune conditions.

28 May 2021

Will emerging SARS-CoV-2 variants affect T cell immunity? A meta-analysis

New research by a team of scientists at The Hong Kong University of Science and Technology sheds light on the epitopic targets of SARS-CoV-2 by T cells in COVID-19 convalescents. The team’s findings suggest that the epitopes targeted by T cells during infection may not be affected by the emergence of SARS-CoV-2 variants.

28 May 2021

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

The Montreal Heart Institute announces that the COLCORONA study results are published today in The Lancet Respiratory Medicine.

28 May 2021

Study may lead to new treatments that eliminate cancer cells without harming other body cells

Normal cells usually have multiple solutions for fixing problems. For example, when DNA becomes damaged, healthy white blood cells can use several different strategies to make repairs.

28 May 2021

Researchers discover cross-reactive coronavirus antibody triggered during COVID-19 infection

Even before the COVID-19 pandemic, most people in the United States already had been sick with a coronavirus, albeit a far less dangerous one.

28 May 2021

Scientists investigate sex-targeted drug delivery for traumatic brain injuries

New research has determined that the window of opportunity to provide possible treatments for patients suffering from traumatic brain injuries (TBIs) differs depending on whether the patient is male or female.

28 May 2021

Researchers use new technique to visualize brain tissue noninvasively

The way the human brain works remains, to a great extent, a topic of controversy. One reason is our limited ability to study neuronal processes at the level of single cells and capillaries across the entire living brain without employing highly invasive surgical methods. This limitation is now on the brink of change.

28 May 2021

Noble False Widow Spiders have public health implications, shows study

NUI Galway study confirms that the Noble False Widow spider does have public health implications. Research team have established a DNA database to allow clinicians dealing with cases to confirm the species identity using genetic analysis

27 May 2021

Study explains why the same exercise have different effects in different people

Although everyone can benefit from exercise, the mechanistic links between physical fitness and overall health are not fully understood, nor are the reasons why the same exercise can have different effects in different people.

27 May 2021

Blood News and Research

SARS-CoV-2 variants partially escape humoral immunity, but not T cells responses, study finds

Novel protein interactions with ACE2 disrupted by SARS-CoV-2, contributes to COVID-19 pathologies

Neuropathology of COVID-19 patients caused by infection of brain pericytes

Study could help identify risk of secondary leukaemia in certain children

New study may help improve stem cell transplantation, lead to better drugs

Kinase inhibitors could provide an effective way to treat high-risk leukaemia

New system can measure propofol concentration in patient's blood during surgery

Blood oxygen levels may explain why memory loss is an early symptom of Alzheimer's disease

Heart Failure 2021 to showcase latest evidence on prevention, management of heart failure

AMA announces e-learning modules to standardize blood pressure measurement training across U.S. medical schools

Mass screening reveals significantly higher numbers of coeliac disease cases in children

Loss of gut epithelial barrier responsible for COVID-19-related MIS-C in children, suggests study

Will emerging SARS-CoV-2 variants affect T cell immunity? A meta-analysis

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

Study may lead to new treatments that eliminate cancer cells without harming other body cells

Researchers discover cross-reactive coronavirus antibody triggered during COVID-19 infection

Scientists investigate sex-targeted drug delivery for traumatic brain injuries

Researchers use new technique to visualize brain tissue noninvasively

Noble False Widow Spiders have public health implications, shows study

Study explains why the same exercise have different effects in different people

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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