Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Protecting or boosting neurotrophins may slow progression of Huntington's disease

A drug that acts like a growth-promoting protein in the brain reduces degeneration and motor deficits associated with Huntington's disease in two mouse models of the disorder, according to a study appearing November 27 in the Journal of Neuroscience. The findings add to a growing body of evidence that protecting or boosting neurotrophins - the molecules that support the survival and function of nerve cells - may slow the progression of Huntington's disease and other neurodegenerative disorders.

27 Nov 2013

Inhibitor compounds could form basis of new treatments for such diseases as MRSA, anthrax

Inhibitor compounds developed by UC Irvine structural biologists and Northwestern University chemists have been shown to bolster the ability of antibiotics to treat deadly bacterial diseases such as MRSA and anthrax.

27 Nov 2013

Principal investigators at Nationwide Children's Hospital elected as AAAS Fellows

Brian K. Kaspar, PhD, and Veronica J. Vieland, PhD, principal investigators in The Research Institute at Nationwide Children's Hospital, have been named Fellows of the American Association for the Advancement of Science (AAAS).

26 Nov 2013

Study investigates connections between sleep problems and neurodegenerative conditions

A new discovery may help explain the surprisingly strong connections between sleep problems and neurodegenerative conditions such as Alzheimer's disease.

26 Nov 2013

Researchers identify new mechanism that causes neurodegeneration

As we age, our body rhythms lose time before they finally stop. Breaking the body clock by genetically disrupting a core clock gene, Bmal1, in mice has long been known to accelerate aging , causing arthritis, hair loss, cataracts, and premature death.

26 Nov 2013

Multiple sclerosis researchers receive NMSS drug development grant

A $500,000 drug development grant from the National Multiple Sclerosis Society was awarded to a partnership between a multiple sclerosis research team at the Icahn School of Medicine at Mount Sinai and Karyopharm Therapeutics Inc., a clinical stage pharmaceutical company. Dr. Patrizia Casaccia, MD, PhD, Professor in the Departments of Neuroscience and Genetics and Genomics, at Icahn School of Medicine at Mount Sinai, will be the academic lead.

21 Nov 2013

New biomarker predicts that concussion victims may have cognitive dysfunction following mTBI

A new blood biomarker correctly predicted which concussion victims went on to have white matter tract structural damage and persistent cognitive dysfunction following a mild traumatic brain injury.

20 Nov 2013

Scientists join patients to address Friedreich's Ataxia

The Spanish Federation of Ataxia (FEDAES)—in representation of the GENEFA Platform for a Friedreich's Ataxia cure—, the Babel Family association for biomedical research into Friedreich's Ataxia, the "Centro de Biología Molecular Severo Ochoa" (CMBSO), and the Institute for Research in Biomedicine (IRB Barcelona) have signed an agreement through which these patients' associations will fund, by means of donations, a 3-year research project addressing Friedreich's Ataxia.

16 Nov 2013

Sanford-Burnham scientists receive grant to assess potential toxicity of large collections of chemicals

A bicoastal group of scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) was recently awarded a three-year grant from the U.S. Department of the Air Force to assess the potential toxicity of large collections of chemicals.

13 Nov 2013

Linkam Scientific Instruments report the use of CMS196 for the imaging of mammalian cells at the London Research Institute, Cancer Research UK

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their innovative CMS196 cryo stage for the study of mammalian cells at the London Research Institute, Cancer Research UK.

From Linkam Scientific Instruments 5 Nov 2013

NIH selects two leading researchers to chair panels at geroscience symposium

The National Institutes of Health (NIH) has chosen two leading aging researchers at Albert Einstein College of Medicine of Yeshiva University to chair panels at the first symposium on "geroscience"-the study of how aging influences the onset of chronic diseases.

30 Oct 2013

Discovery sheds light on how forces outside of cells get translated into internal signals

Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities.

21 Oct 2013

Motor neurone disease neck collars: an interview with Dr Christopher J McDermott, Clinical Senior Lecturer, University of Sheffield

The majority of the current neck support collars for MND patients were designed for a different purpose. So, if you think about when people are involved in a road traffic accident, the paramedics arrive and put a collar on to immobilize the neck and protect the spine. A lot of the collars that we give to our patients with MND were actually designed for that purpose - to immobilize the necks of people involved in trauma… and patients don't want that.

18 Oct 2013

Brain scientists to explore current biological, psychosocial and ecological aspects of memory loss disorders

"From Neurodegeneration to Brain Health: An Integrated Approach" is a conference that will bring together distinguished brain scientists to explore the current biological, psychosocial and ecological aspects of memory loss disorders.

18 Oct 2013

Study: Sleep allows brain to flush out damaging molecules linked with neurodegeneration

A good night's rest may literally clear the mind. Using mice, researchers showed for the first time that the space between brain cells may increase during sleep, allowing the brain to flush out toxins that build up during waking hours.

18 Oct 2013

Genetics professor turns accidental discovery into a way to study TBI

Faced with news of suicides and brain damage in former professional football players, geneticist Barry Ganetzky bemoaned the lack of model systems for studying the insidious and often delayed consequences linked to head injuries.

16 Oct 2013

Epigenetic regulation linked with pathogenesis of Alzheimer's disease

New evidence presented at the 26th ECNP Congress linking epigenetic regulation with Alzheimer's disease may one day lead to new early diagnostic tests and even novel treatment options for the most common form of dementia.

7 Oct 2013

Resveratrol worsens MS-like neuropathology and inflammation, study finds

Resveratrol, a naturally occurring polyphenol compound produced by the skin of red grapes and peanuts, and found in red wine, has been touted as a beneficial supplement due to its anti-inflammatory and antioxidant properties.

1 Oct 2013

Dynamics of the mitochondria linked to obesity

Becoming obese or remaining lean can depend on the dynamics of the mitochondria, the body's energy-producing "battery," according to two new studies by Yale School of Medicine researchers featured as the cover story in the Sept. 26 issue of the journal Cell.

27 Sep 2013

Targeting cell-division cycle may lead to improved outcomes for patients with medulloblastoma

A new experimental approach to treating a type of brain cancer called medulloblastoma has been developed by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham).

26 Sep 2013

Neurodegeneration News and Research

Further Reading

Protecting or boosting neurotrophins may slow progression of Huntington's disease

Inhibitor compounds could form basis of new treatments for such diseases as MRSA, anthrax

Principal investigators at Nationwide Children's Hospital elected as AAAS Fellows

Study investigates connections between sleep problems and neurodegenerative conditions

Researchers identify new mechanism that causes neurodegeneration

Multiple sclerosis researchers receive NMSS drug development grant

New biomarker predicts that concussion victims may have cognitive dysfunction following mTBI

Scientists join patients to address Friedreich's Ataxia

Sanford-Burnham scientists receive grant to assess potential toxicity of large collections of chemicals

Linkam Scientific Instruments report the use of CMS196 for the imaging of mammalian cells at the London Research Institute, Cancer Research UK

NIH selects two leading researchers to chair panels at geroscience symposium

Discovery sheds light on how forces outside of cells get translated into internal signals

Motor neurone disease neck collars: an interview with Dr Christopher J McDermott, Clinical Senior Lecturer, University of Sheffield

Brain scientists to explore current biological, psychosocial and ecological aspects of memory loss disorders

Study: Sleep allows brain to flush out damaging molecules linked with neurodegeneration

Genetics professor turns accidental discovery into a way to study TBI

Epigenetic regulation linked with pathogenesis of Alzheimer's disease

Resveratrol worsens MS-like neuropathology and inflammation, study finds

Dynamics of the mitochondria linked to obesity

Targeting cell-division cycle may lead to improved outcomes for patients with medulloblastoma

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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