Severe Acute Respiratory News and Research

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NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

In a recent study posted to the bioRxiv* preprint server, researchers at the U.S National Institutes of Health demonstrated the efficacy of molnupiravir and nirmatrelvir, two oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals in the rhesus macaque model, the closest proxy to humans.

7 Sep 2022

Techniques used for SARS-CoV-2 detection in body fluids

In a recent review published in the journal Trends in Analytical Chemistry, researchers provided a comprehensive overview of the current techniques used for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in bodily fluids.

7 Sep 2022

Persistent cardiac symptoms in individuals with mild initial COVID-19

In a recent study published in the journal Nature Medicine, researchers conducted serial cardiac assessments in individuals with mild initial coronavirus disease 2019 (COVID-19) who had no history of cardiac disease and significant comorbidities.

7 Sep 2022

The associations between vaccination status, type, and time since vaccination with lineage identity during the emergence of new SARS-CoV-2 variants

Researchers assessed the association between SARS-CoV-2 strains and patient age, COVID-19 vaccination status, vaccine type, and days elapsed since the most recent vaccination among New York residents.

7 Sep 2022

Plant production of nanobodies that neutralize the interaction between ACE2 receptor and SARS-CoV-2 spike protein

Researchers demonstrated the production of nanobodies against SARS-CoV-2 spike protein.

7 Sep 2022

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Researchers performed the photocatalytic mapping of the SARS-CoV-2 spike protein-host cell membrane interactions.

7 Sep 2022

Researchers identify novel neutralizing monoclonal antibodies against SARS-CoV-2 in vaccinated individuals after wildtype infection

Researchers identified monoclonal antibodies that neutralize SARS-CoV-2 variants.

7 Sep 2022

How have worldwide physical activity trends changed since the onset of the COVID-19 pandemic?

Researchers assessed the trends in physical activity worldwide since the onset of COVID-19.

7 Sep 2022

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

Researchers investigated the prevalence, genomic diversity, and evolution of SARS-CoV-2 among white-tailed deers in New York.

6 Sep 2022

Review explores the involvement of the endothelium as an important underpinning of long COVID’s pathophysiology

Researchers discussed possible mechanisms and potential treatment methods for endotheliopathy observed in patients with post-acute sequelae of SARS-CoV-2 infection.

6 Sep 2022

What is currently known about the mechanism and treatments of long COVID?

The current understanding of the mechanisms underlying long COVID or post-acute sequelae of COVID and potential treatment methods that show promise in long COVID management.

6 Sep 2022

Study suggests entry of SARS-CoV-2 requires an acidic pH

Researchers carried out real-time single-virion tracking in three dimensions to study the mechanisms and requirements of membrane attachment and fusion of SARS-CoV-2 with the host cell.

6 Sep 2022

Auranofin inhibits SARS-CoV-2 replication

In a new ISCIENCE journal study, scientists identified an FDA-approved NF-κB inhibitor, Auranofin, which can also control inflammation.

6 Sep 2022

Monkeypox infection causing acute myocarditis - case report

A recent case report published in the journal JACC Case Reports indicated that monkeypox infection might be associated with acute myocarditis or heart muscle inflammation.

5 Sep 2022

Are current COVID-19 vaccines in England effective against severe BA.4 and BA.5 Omicron sub-lineage infections?

Researchers investigated the vaccine efficacy of various COVID-19 vaccines against the BA.2, BA.4, and BA.5 sub-lineages of the SARS-CoV-2 Omicron variant.

5 Sep 2022

Sensitivity of SARS-CoV-2 Omicron BA.2.75 to neutralization by monoclonal antibodies and sera

Researchers assessed the sensitivity of the SARS-CoV-2 Omicron subvariant BA.2.75 spike protein to neutralization by monoclonal antibodies and sera obtained from Swedish individuals.

5 Sep 2022

Study suggests loss of smell and brain inflammation are independent in COVID-19

Researchers assessed the association between neuroinvasion and anosmia observed during COVID-19.

5 Sep 2022

What is the impact of inter-individual heterogeneity on the degree and duration of vaccinal protection against mild and severe COVID-19?

Researchers suggested ways to address heterogeneity in immune responses conferred by COVID-19 vaccines.

5 Sep 2022

Researchers compare the percent excess mortalities due to the zero-COVID-19 policy or the living-with-COVID policy

Researchers compared the percent excess mortalities due to the zero-COVID-19 policy or the living-with-COVID policy.

5 Sep 2022

The possible association between SARS-CoV-2, ACE2, TMPRSS2, and skin manifestations

A new study analyzed the possibility of penetration of SARS-CoV-2 into the skin.

5 Sep 2022

Severe Acute Respiratory News and Research

NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

Techniques used for SARS-CoV-2 detection in body fluids

Persistent cardiac symptoms in individuals with mild initial COVID-19

The associations between vaccination status, type, and time since vaccination with lineage identity during the emergence of new SARS-CoV-2 variants

Plant production of nanobodies that neutralize the interaction between ACE2 receptor and SARS-CoV-2 spike protein

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Researchers identify novel neutralizing monoclonal antibodies against SARS-CoV-2 in vaccinated individuals after wildtype infection

How have worldwide physical activity trends changed since the onset of the COVID-19 pandemic?

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

Review explores the involvement of the endothelium as an important underpinning of long COVID’s pathophysiology

What is currently known about the mechanism and treatments of long COVID?

Study suggests entry of SARS-CoV-2 requires an acidic pH

Auranofin inhibits SARS-CoV-2 replication

Monkeypox infection causing acute myocarditis - case report

Are current COVID-19 vaccines in England effective against severe BA.4 and BA.5 Omicron sub-lineage infections?

Sensitivity of SARS-CoV-2 Omicron BA.2.75 to neutralization by monoclonal antibodies and sera

Study suggests loss of smell and brain inflammation are independent in COVID-19

What is the impact of inter-individual heterogeneity on the degree and duration of vaccinal protection against mild and severe COVID-19?

Researchers compare the percent excess mortalities due to the zero-COVID-19 policy or the living-with-COVID policy

The possible association between SARS-CoV-2, ACE2, TMPRSS2, and skin manifestations

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Why use light scattering to analyze proteins and viral vectors?

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