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Association between SARS-CoV-2 Omicron viral load and vaccination history

Researchers analyzed the association between viral loads in SARS-CoV-2 Omicron variant infection and vaccination history.

21 Apr 2022

Study evaluates SARS-CoV-2 whole genome data from patients and staff in the VA Northeast Ohio Healthcare System

Researchers surveyed over 360 COVID-19 patients to characterize the SARS-CoV-2 genomic sequence diversity of individual infections.

21 Apr 2022

New insight into SARS-CoV-2 main protease opens door to new viral inhibitors

A recent study has revealed a full cycle of substrate cleavage for the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – providing, in turn, a steadfast foundation for developing potent new viral inhibitors. The paper was published in the journal Proceedings of the National Academy of Sciences (PNAS).

20 Apr 2022

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

In a new study, researchers assessed the impact of the SARS-CoV-2 Omicron variant on infected human cells and organs.

20 Apr 2022

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Researchers demonstrated ocular tropism of SARS-CoV-2 through neuronal invasion in transgenic mice with hACE2 expression.

20 Apr 2022

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

New, longest documented case of persistent acute SARS-CoV-2 infection

Researchers describe a 16-month-old case of SARS-CoV-2 infection in an immunocompromised individual.

18 Apr 2022

Role of cGAS-STING in SARS-CoV-2 infection

A new study analyzes the activation of cGAS and STING can induce a type I IFN response due to SARS-CoV-2 infection.

15 Apr 2022

Cell’s production of lipids can be a key factor in determining cell fate

How does a cell "decide" what type of cell to become? The question of "cell fate" has been explored for decades now, especially in the context of stem cell biology, but there are still gaps in our understanding.

15 Apr 2022

Scientists discover differences in interaction of T-cells within tumor microenvironments

A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according to findings published in the journal JCI Insight.

14 Apr 2022

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

A new study investigated whether APOBEC proteins can directly edit the RNA sequence of SARS-CoV-2 to generate C-to-U mutations.

14 Apr 2022

Study reveals natural infection of pangolins with human RSV

A new study aimed to determine whether humans were able to transmit RSV to Malayan pangolins.

13 Apr 2022

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

A new study addresses the relationship between SARS-CoV-2 to the metabolism of one-carbon molecules in the host, suggesting new therapeutic pathways.

13 Apr 2022

Dietary influences on long COVID in children

A new study discusses possible mechanisms of long COVID in children and how they might relate to their dietary intake of important vitamins and elements.

13 Apr 2022

Quantum computing to predict RNA secondary structures

Researchers investigate the possibility of using quantum computing to create methods that can more effectively and rapidly solve these structures.

13 Apr 2022

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

Alternative splicing is a fundamental biological process that allows cells to make many different types of mRNAs and proteins from a limited number of genes. For many animals, including humans, it is a feature that is essential for the development of complex cells such as muscles or neurons.

13 Apr 2022

Researchers find novel inhibitors that may suppress oncogenesis of metastatic prostate cancer

Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate into and invade surrounding structures.

13 Apr 2022

Case of probable transmission of tick-borne encephalitis virus from an unvaccinated mother to an infant through breast-feeding

A recent study discusses a case report of the probable vertical transmission of tick-borne encephalitis virus (TBEV) from an unvaccinated mother to her newborn via breast milk.

13 Apr 2022

Researchers discover new way to inhibit key mutated gene underlying tumor growth

CU Boulder researchers have discovered a new way to inhibit the most commonly mutated gene underlying human tumor growth, opening the door to new therapeutic strategies for cancer and a host of other diseases.

12 Apr 2022

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

In a new study, researchers quantified the serological responses following the third dose of mRNA-based COVID-19 vaccines in patients with hematological malignancies.

12 Apr 2022

Transcription News and Research

Association between SARS-CoV-2 Omicron viral load and vaccination history

Study evaluates SARS-CoV-2 whole genome data from patients and staff in the VA Northeast Ohio Healthcare System

New insight into SARS-CoV-2 main protease opens door to new viral inhibitors

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

New, longest documented case of persistent acute SARS-CoV-2 infection

Role of cGAS-STING in SARS-CoV-2 infection

Cell’s production of lipids can be a key factor in determining cell fate

Scientists discover differences in interaction of T-cells within tumor microenvironments

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

Study reveals natural infection of pangolins with human RSV

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

Dietary influences on long COVID in children

Quantum computing to predict RNA secondary structures

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

Researchers find novel inhibitors that may suppress oncogenesis of metastatic prostate cancer

Case of probable transmission of tick-borne encephalitis virus from an unvaccinated mother to an infant through breast-feeding

Researchers discover new way to inhibit key mutated gene underlying tumor growth

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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