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Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Whitehead Institute scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within the cellular organelles known as mitochondria, often referred to as the "powerhouses of the cell."

31 Aug 2016

Research findings could lead to new biomarker for early stages of tumor development

To treat or not to treat? That is the question researchers at the Department of Energy's Lawrence Berkeley National Laboratory hope to answer with a new advance that could help doctors and their cancer patients decide if a particular therapy would be worth pursuing.

31 Aug 2016

MRSA correlated to eczema? An interview with Dr Bjorn Herpers

There is a lot of evidence that Staphylococcus aureus (S. aureus) is involved in eczema. Eczema is now thought to be caused by a barrier dysfunction of the skin that allows external triggers to cause an overshoot of inflammation.

31 Aug 2016

Investigational biomarker surpasses current gold standard test for identifying brain shunt infections

In a study of children with brain shunts at Children's of Alabama, a University of Alabama at Birmingham investigational biomarker outperformed the current "gold standard" test for detecting bacterial infections in the shunts.

30 Aug 2016

Study shows how caffeine counteracts age-related cognitive deficits in animals

A study published in the journal Scientific Reports from Nature publishing group, describes the mechanism by which caffeine counteracts age-related cognitive deficits in animals.

30 Aug 2016

New research shows female mosquitoes can pass Zika virus to their offsprings

New research from The University of Texas Medical Branch in Galveston has shown that female Aedes aegypti mosquitoes can pass the Zika virus to their eggs and offspring.

30 Aug 2016

New discovery could lead to effective treatment methods for cystitis

Every year, millions of people are treated for cystitis, but despite its prevalence, the disease is still a scientific mystery.

30 Aug 2016

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

In a study focusing on the role of self-donated (autologous) bone marrow-derived endothelial progenitor cells (EPCs) in placental vascular development, researchers in Japan have discovered that when transplanted into pregnant mice, EPCs can contribute to better blood vessel growth that helps in forming "normalized" placental vascularization, leading, in turn, to reduced recurrent miscarriages by providing a healthier fetal environment during gestation.

30 Aug 2016

Deficiency in important enzyme leads to alcohol dependency

A research group under the leadership of Linköping University Professor Markus Heilig has identified an enzyme whose production is turned off in nerve cells of the frontal lobe when alcohol dependence develops.

30 Aug 2016

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool.

30 Aug 2016

CFS possesses objectively identifiable chemical signature in men and women, study reveals

Dauer is the German word for persistence or long-lived. It is a type of stasis in the development in some invertebrates that is prompted by harsh environmental conditions. The findings are published online in the August 29 issue of PNAS.

29 Aug 2016

Scripps collaborates with MD Anderson for clinically integrated cancer care program

Scripps Health and The University of Texas MD Anderson Cancer Center have reached a partnership agreement to create Scripps MD Anderson Cancer Center, a comprehensive and clinically integrated cancer care program in San Diego that will provide adult cancer patients greater access to the most advanced oncology care available throughout Southern California.

29 Aug 2016

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

In microseconds, every light ray that enters the eye triggers an explosion of coordinated cellular events.

29 Aug 2016

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer.

29 Aug 2016

Studying mutant peptides may help detect weaknesses in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing.

29 Aug 2016

Cleft palate repair costs the same for internationally adopted children

Since 2009, United States residents have adopted more children from China than any other country. Since China has a high prevalence of cleft lip and palate, some of these children require extra medical care early in their lives. Many prospective families are fearful of the treatment costs needed by a child affected by cleft lip and palate. However, recent research suggests that the costs are not nearly as high as previously thought.

29 Aug 2016

Blade implants in oral surgery still successful after 50 years

Journal of Oral Implantology – For nearly 50 years, the unique design of the blade implant and the ease of inserting it into a patient’s mouth have made it popular among oral surgeons. As the implant’s golden jubilee approaches, some of its original designers take a new look at a creation that has “passed the test of time.”

29 Aug 2016

Mediterranean Diet linked to mortality risk reduction in patients with cardiovascular disease

The Mediterranean diet is associated with a reduced risk of death in patients with a history of cardiovascular disease, according to results from the observational Moli-sani study presented at ESC Congress 2016 today.

28 Aug 2016

Skin cells derived from autistic donors grow faster than those from control subjects

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, chair of the department of genetics and genome sciences at Case Western Reserve University School of Medicine.

28 Aug 2016

Moderate physical activity reduces risk of acute cardiovascular event in older people

Moderate physical activity is associated with a greater than 50% reduction in cardiovascular death in over-65s, according to research presented at ESC Congress 2016 today. The 12 year study in nearly 2500 adults aged 65 to 74 years found that moderate physical activity reduced the risk of an acute cardiovascular event by more than 30%. High levels of physical activity led to greater risk reductions.

27 Aug 2016

Laboratory News and Research

Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Research findings could lead to new biomarker for early stages of tumor development

MRSA correlated to eczema? An interview with Dr Bjorn Herpers

Investigational biomarker surpasses current gold standard test for identifying brain shunt infections

Study shows how caffeine counteracts age-related cognitive deficits in animals

New research shows female mosquitoes can pass Zika virus to their offsprings

New discovery could lead to effective treatment methods for cystitis

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

Deficiency in important enzyme leads to alcohol dependency

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

CFS possesses objectively identifiable chemical signature in men and women, study reveals

Scripps collaborates with MD Anderson for clinically integrated cancer care program

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

Studying mutant peptides may help detect weaknesses in tumor cells

Cleft palate repair costs the same for internationally adopted children

Blade implants in oral surgery still successful after 50 years

Mediterranean Diet linked to mortality risk reduction in patients with cardiovascular disease

Skin cells derived from autistic donors grow faster than those from control subjects

Moderate physical activity reduces risk of acute cardiovascular event in older people

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