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Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

A group of researchers from various institutes in the USA addressed the limitations of BAT therapy by transplanting a low dose of brown adipocytes (BAs) without Matrigel to determine if this could alleviate high-fat diet-induced OB, metabolic symptoms, and T2DM in mice.

18 Oct 2021

Delta and Delta Plus infect lung cells with higher efficiency than the original virus, research shows

The emergence of new SARS-CoV-2 variants that can spread rapidly and undermine vaccine-induced immunity threatens the end of the COVID-19 pandemic. The delta variant (B.1.617.2) emerged in India and subsequently spread globally within a short time period. Also in Germany, almost all recent infections are due to this variant.

18 Oct 2021

Common treatment for MIS-C patients likely works by depleting neutrophils

Intravenous immune globulin (IVIG) — a common treatment for multisystem inflammatory syndrome in children (MIS-C) — likely works by depleting immune cells called neutrophils, according to a recent study funded by the National Institutes of Health.

15 Oct 2021

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system.

15 Oct 2021

Generating Cell Repellent Surfaces in Microfluidic Devices

AMSBIO report that researchers from the Medical University of Vienna (Austria), have used Lipidure® - CM5206 to coat channels in their novel microfluidic devices, to prevent cell adhesion.

From AMS Biotechnology 15 Oct 2021

New atlas of small cell lung cancer reveals rare population of stem-like cells with metastatic properties

Imagine you're about to go on a cross-country trip, stopping at spots along the way to admire local attractions.

15 Oct 2021

Daily use of cannabidiol oil may shrink lung tumors

It may be worth exploring further the use of cannabidiol ('CBD') oil as a potential lung cancer treatment, suggest doctors in BMJ Case Reports after dealing with a daily user whose lung tumor shrank without the aid of conventional treatment.

15 Oct 2021

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

The efficacy and safety of a DNA-based vaccine are investigated, finding that the unique vaccine imparts a robust and long-lasting immunogenic response.

15 Oct 2021

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

The results of a phase 2 clinical trial featuring a SARS-CoV-2 recombinant protein vaccine developed by GlaxoSmithKline are reported, demonstrating a favorable immune response amongst both naïve and non-naïve adults with an acceptable safety profile.

15 Oct 2021

Advancing ethical recombinant antibody research with the customer in mind

In this interview, News-Medical speaks to Dr. Tillmann Ziegert, Managing Director at Biorbyt Ltd, about the balance between enhancing ethical research opportunities and keeping customers at center stage.

From Biorbyt 15 Oct 2021

Study detects the presence of SARS-CoV-2 in semen along with low sperm count

A new study reported findings of semen analysis from a prospective COVID-19 cohort study.

15 Oct 2021

Cell-based quadrivalent influenza vaccine produces sufficient immune response in children

A cell-based influenza vaccine has effectively provided protection against the flu in children and adolescents, according to a new study.

15 Oct 2021

Study unravels new mechanism for muscle repair after physiological damage

Muscle is known to regenerate through a complex process that involves several steps and relies on stem cells. Now, a new study led by researchers at Pompeu Fabra University (UPF, Spain)/Centro Nacional de Investigationes Cardiovasculares (CNIC, Spain)/CIBERNED (Spain) and Instituto de Medicina Molecular João Lobo Antunes (iMM, Portugal), published on 15 October in the journal Science, describes a new mechanism for muscle repair after physiological damage relying on the rearrangement of muscle fiber nuclei, and independently of muscle stem cells.

15 Oct 2021

Study explains how stem cells can help lizards regenerate better tails

Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, the replacement structure is an imperfect cartilage tube.

15 Oct 2021

New discovery suggests potential treatment target for osteoporosis and rheumatoid arthritis

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis.

14 Oct 2021

Study reveals a detrimental role of the immune system in Lewy body dementias

T-cells respond to buildups of alpha-synuclein, the aggregated protein clumps that are a feature of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease (PD), according to a Northwestern Medicine study published in Science.

14 Oct 2021

Cell News and Research

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

Delta and Delta Plus infect lung cells with higher efficiency than the original virus, research shows

Common treatment for MIS-C patients likely works by depleting neutrophils

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

Generating Cell Repellent Surfaces in Microfluidic Devices

New atlas of small cell lung cancer reveals rare population of stem-like cells with metastatic properties

Daily use of cannabidiol oil may shrink lung tumors

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

Advancing ethical recombinant antibody research with the customer in mind

Study detects the presence of SARS-CoV-2 in semen along with low sperm count

Cell-based quadrivalent influenza vaccine produces sufficient immune response in children

Study unravels new mechanism for muscle repair after physiological damage

Study explains how stem cells can help lizards regenerate better tails

New discovery suggests potential treatment target for osteoporosis and rheumatoid arthritis

Study reveals a detrimental role of the immune system in Lewy body dementias

Study reveals a highly effective COVID-19 screening system utilizing a live cell-based assay

SARS-CoV-2 induces tissue immune memory

Increased transmission in open spike conformations of SARS-CoV-2 variants

Mutation of cysteine residues in NRP1 reduces SARS-CoV-2 spike protein entry into cells

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics