Acetaminophen News and Research

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The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

Novartis to showcase 160 presentations on breast cancer, hematological disease drugs at SABCS and ASH

Novartis Pharmaceuticals Corporation will showcase more than one hundred and sixty presentations on data from its robust oncology portfolio at two key medical congresses this month, demonstrating significant advances for patients with cancers and hematological diseases.

3 Dec 2011

Acetaminophen over-use can lead to serious liver damage

Common pain and fever Acetaminophen (best known by the brand name Tylenol) taken over a long time can cause liver failure and death, according to a new study.

24 Nov 2011

Study reveals principal mechanism of action for paracetamol

Researchers at King's College London have discovered how one of the most common household painkillers works, which could pave the way for less harmful pain relief medications to be developed in the future.

23 Nov 2011

Covidien fourth quarter net sales increase 15% to $3.08 billion

Covidien plc today reported results for the fourth quarter of fiscal 2011.

15 Nov 2011

Low-grade inflammatory processes drive development of osteoarthritis

In a study to be published online Nov. 6 in Nature Medicine, investigators at the Stanford University School of Medicine have shown that the development of osteoarthritis is in great part driven by low-grade inflammatory processes.

8 Nov 2011

APF launches new online educational module on safe use of CAM

The American Pain Foundation (APF) announced the launch of a new online educational module focusing on safe use of complementary and alternative medicine (CAM) as part of its PainSAFE initiative.

5 Nov 2011

Ferring reports on FDA approval of labeling supplement for EUFLEXXA to treat knee osteoarthritis

On Oct. 11, 2011, the FDA approved a labeling supplement for EUFLEXXA (1% sodium hyaluronate) that provides 26-week efficacy data from the FLEXX trial, as well as, 52-week safety data to demonstrate the safety of repeated injection cycles.

22 Oct 2011

Multimodal analgesia is used less than 25% of the time prior to surgery

Many surgical patients are concerned about the level of pain they will experience. In a new study presented at ANESTHESIOLOGY 2011, researchers from Thomas Jefferson University identified that multimodal analgesia, a combination of pain medication and therapeutic measures to improve pain control, is used less than 25 percent of the time prior to surgery.

19 Oct 2011

Nearly 30% of homes with young children have acetaminophen products stored unsafely

Nearly 30 percent of homes with young children have acetaminophen products stored unsafely, and nearly all homes included at least one expired medication, according to a research abstract presented Monday, Oct. 17, at the American Academy of Pediatrics (AAP) National Conference and Exhibition in Boston.

18 Oct 2011

Tailored postoperative treatment plan for women at high risk for severe pain after cesarean delivery

Nearly one third of children in the U.S. are born by cesarean delivery, a surgery that puts women at risk for persistent pain and postpartum depression. A new study presented at ANESTHESIOLOGY 2011 investigated whether an increase in pain treatment in patients at high risk for severe pain after surgery reduces these complications after a cesarean delivery.

18 Oct 2011

APhA encourages patients to discuss with pharmacist about pain and medications

In honor of Pain Awareness Month, the American Pharmacists Association (APhA) encourages patients to have an open discussion with their pharmacist about their pain and the medications they take for pain.

30 Sep 2011

GSA's two forthcoming publications focus on pain relief and medication for seniors

To highlight Pain Awareness Month in September, The Gerontological Society of America (GSA) - the nation's largest interdisciplinary organization devoted to the field of aging - is announcing two forthcoming publications focused on pain relief and medication for seniors.

16 Sep 2011

Inhibition of Sab protein protects liver from acetaminophen toxicity

New research from the Keck School of Medicine of the University of Southern California (USC) may help prevent damage to the liver caused by drugs like acetaminophen and other stressors.

8 Sep 2011

Simple pain relievers a better alternative to antipsychotic medications for dementia patients

Many dementia patients are being treated with antipsychotic medications, but a new study shows that simple pain relievers may be a better alternative.

8 Sep 2011

Oxycodone no safer than codeine for breastfed infants: New study

Doctors have been prescribing codeine for postpartum pain management for many years, and, until recently, it was considered safe to breastfeed while taking the opioid. But the death of an infant exposed to codeine through breast milk has many health care providers questioning the safety of the drug when used by breastfeeding mothers.

7 Sep 2011

New meta-analysis reaffirms safety profile of aspirin for pain relief, fever

A new meta-analysis published this week in Drugs in R&D, reaffirms the safety profile of aspirin for short-term treatment of mild to moderate pain, and aches and fever due to colds when used as directed.

2 Sep 2011

Dendritic cells play central role in regulation of acetaminophen's toxicity

NYU School of Medicine researchers have discovered that dendritic cells in the liver have a protective role against the toxicity of acetaminophen, the widely used over-the-counter pain reliever and fever reducer for adults and children.

2 Sep 2011

FDA, USP co-sponsors OTC drug products workshop

Updated public standards incorporating new tests for impurities as well as more modern technologies to help ensure the quality of over-the-counter (OTC) ingredients and products will be key areas of focus for a September 8-9, 2011, workshop co-sponsored by the U.S. Food & Drug Administration (FDA) and the U.S. Pharmacopeial Convention.

17 Aug 2011

Labopharm, Angelini enter into agreement to reorganize partnership

Labopharm Inc. and Gruppo Angelini, its partner in the joint venture established by the two companies to commercialize OLEPTRO in the U.S., today announced that they have entered into an agreement to restructure their partnership.

30 Jul 2011

Cadence confirms FDA dosing recommendations for OFIRMEV

Cadence Pharmaceuticals, Inc. today confirmed that the U.S. Food and Drug Administration (FDA) approved dosing recommendations for OFIRMEV (acetaminophen) injection remains 4,000 mg per day for adults and adolescents weighing at least 50 kg.

29 Jul 2011