Acute Myeloid Leukemia News and Research

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Acute Myeloid Leukemia (AML) is a rapidly progressing cancer of the blood characterized by the uncontrolled proliferation of immature blast cells in the bone marrow. The Leukemia and Lymphoma Society estimates that over 13,000 new cases of AML were diagnosed and approximately 9,000 deaths from AML occurred in the U.S. during 2007. AML is generally a disease of older adults, and the median age of a patient diagnosed with AML is about 67 years. A majority of elderly patients are not considered candidates for standard induction therapy or decline therapy, resulting in an acute need for new treatment options.

Leukemic cells are addicted to vitamin B6, research shows

Scientists have discovered that Acute Myeloid Leukemia (AML) grows by taking advantage of the B6 vitamin to accelerate cell division.

13 Jan 2020

Researchers move closer to identifying leukemic stem cells

Acute myeloid leukemia is the most common type of leukemia in adults. It is characterized by the pathological expansion of immature cells (myeloblasts) that invade the bone marrow and expand into the blood, affecting the production of the rest of the healthy cells.

2 Jan 2020

Artificial intelligence can detect AML with high reliability

Artificial intelligence can detect one of the most common forms of blood cancer - acute myeloid leukemia (AML) - with high reliability.

20 Dec 2019

Yale researchers identify cellular chicanery that jumpstarts cancer

The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists believe, to early stage cancer cells that eventually swamp normal cells and become deadly.

18 Dec 2019

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Patients with acute lymphoblastic leukemia or acute myeloid leukemia who are treated with anthracyclines are at a heightened risk of heart failure- most often within one year of exposure to the chemotherapy treatment, according to a new study led by researchers at Penn Medicine.

17 Dec 2019

New therapy shows dramatic effect against worst types of leukaemias

A collaborative research effort by Australian and US scientists has led to the discovery of a promising new approach to treating some of the worst types of leukaemia, including an aggressive leukaemia that mostly affects babies.

11 Dec 2019

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

10 Dec 2019

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

In a clinical trial led by Yale Cancer Center and Smilow Cancer Hospital, researchers aim to exploit DNA mutations in the treatment of two blood and bone marrow cancers, a different tacit than the more traditional approach of blunting or switching off genetic mutations linked to cancer.

10 Dec 2019

Transplant patient finds out his DNA has been replaced by that of his donor

A bone marrow transplant recipient later found out that the DNA in his blood and semen had been replaced by that of his donor.

10 Dec 2019

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations.

9 Dec 2019

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

A multi-institutional, Phase II study led by The University of Texas MD Anderson Cancer Center showed that pairing standard chemotherapy azacitidine (AZA) with a drug called enasidenib (ENA) measurably boosts complete remission in patients newly diagnosed with a specific form of acute myeloid leukemia (AML).

9 Dec 2019

Yale study highlights the need to develop effective, less toxic approaches to treat AML patients

A new study by Yale Cancer Center researchers shows understanding treatment patterns for patients with acute myeloid leukemia is vital to develop strategies to improve outcomes.

9 Dec 2019

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

For patients with high-risk myeloid cancers undergoing a donor stem cell transplant, adding the targeted drug venetoclax to a reduced-intensity drug regimen prior to transplant is safe and does not impair the ability of the donor cells to take root in recipients' bodies, a study led by Dana-Farber Cancer Institute researchers suggests.

8 Dec 2019

Genetic features of AML in older patients can predict outcomes after stem cell transplant

For older patients with acute myeloid leukemia, the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute and other research centers will report today at the 61st American Society of Hematology (ASH) Annual Meeting.

8 Dec 2019

Scientists develop new therapy for acute myeloid leukemia

Cold Spring Harbor Laboratory scientists, with chemists and cancer biologists from Dana-Farber Cancer Institute, have developed a new therapy that extended the survival of mice with acute myeloid leukemia.

19 Nov 2019

New AI-driven approach for single blood cell classification

For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood samples from patients suffering from acute myeloid leukemia.

12 Nov 2019

Fujitsu successfully verifies AI technology to improve efficiency in cancer genomic medicine

Fujitsu has announced the results of a joint research project it has been conducting with the Institute of Medical Science at the University of Tokyo since April 2018.

6 Nov 2019

New guide for genomic diagnosis of myelodysplastic syndromes and chronic myelomonocytic leukemia published

In Spain, a workgroup of more than 400 researchers, the Spanish Group of Myelodysplastic Syndromes, meets twice a year to present projects and undertake collaborations that improve their work in the fight against Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia, two types of blood cancers.

4 Nov 2019

Avocados may hold the key to managing obesity and preventing diabetes

Your guacamole may hold the key to managing obesity and helping delay or prevent diabetes, according to a new study by a University of Guelph research team.

30 Oct 2019

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia and B-cell lymphoma.

21 Oct 2019

Acute Myeloid Leukemia News and Research

Further Reading

Leukemic cells are addicted to vitamin B6, research shows

Researchers move closer to identifying leukemic stem cells

Artificial intelligence can detect AML with high reliability

Yale researchers identify cellular chicanery that jumpstarts cancer

Leukemia patients treated with common cancer drug have heightened risk of heart failure

New therapy shows dramatic effect against worst types of leukaemias

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

Transplant patient finds out his DNA has been replaced by that of his donor

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

Yale study highlights the need to develop effective, less toxic approaches to treat AML patients

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

Genetic features of AML in older patients can predict outcomes after stem cell transplant

Scientists develop new therapy for acute myeloid leukemia

New AI-driven approach for single blood cell classification

Fujitsu successfully verifies AI technology to improve efficiency in cancer genomic medicine

New guide for genomic diagnosis of myelodysplastic syndromes and chronic myelomonocytic leukemia published

Avocados may hold the key to managing obesity and preventing diabetes

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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