Acute Myeloid Leukemia News and Research

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Acute Myeloid Leukemia (AML) is a rapidly progressing cancer of the blood characterized by the uncontrolled proliferation of immature blast cells in the bone marrow. The Leukemia and Lymphoma Society estimates that over 13,000 new cases of AML were diagnosed and approximately 9,000 deaths from AML occurred in the U.S. during 2007. AML is generally a disease of older adults, and the median age of a patient diagnosed with AML is about 67 years. A majority of elderly patients are not considered candidates for standard induction therapy or decline therapy, resulting in an acute need for new treatment options.
Study reveals impact of TP53 gene mutations on MDS severity

Study reveals impact of TP53 gene mutations on MDS severity

Study sheds light on potential new treatment approach in AML patients

Study sheds light on potential new treatment approach in AML patients

Researchers identify specific target sites for DNA methylases

Researchers identify specific target sites for DNA methylases

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Mapping immune landscape of hematological malignancies may help improve cancer therapies

New nanoconjugate blocks dissemination of tumor cells in animal models of acute myeloid leukemia

New nanoconjugate blocks dissemination of tumor cells in animal models of acute myeloid leukemia

Researchers receive innovative grants to understand the biological underpinnings of blood cancers

Researchers receive innovative grants to understand the biological underpinnings of blood cancers

Researchers discover new and improved way to treat poor-prognosis blood cancer

Researchers discover new and improved way to treat poor-prognosis blood cancer

Researchers call for caution of using CAR-T immunotherapy against AML

Researchers call for caution of using CAR-T immunotherapy against AML

Two potent small molecules appear to suppress tumor growth in multiple cancers

Two potent small molecules appear to suppress tumor growth in multiple cancers

New leukemia immune profiles predict drug resistance, positive responses to immunotherapy

New leukemia immune profiles predict drug resistance, positive responses to immunotherapy

Researchers discover key gene essential for survival of leukemia stem cells

Researchers discover key gene essential for survival of leukemia stem cells

KinaRx receives SBIR grant to speed up clinical trials for AML and other diseases

KinaRx receives SBIR grant to speed up clinical trials for AML and other diseases

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Indiana researchers identify new target for colorectal cancer immunotherapy

Indiana researchers identify new target for colorectal cancer immunotherapy

More selective elimination of leukemic and hematopoietic stem cells

More selective elimination of leukemic and hematopoietic stem cells

Kurome secures license to develop novel therapies for chemo-resistant cancer

Kurome secures license to develop novel therapies for chemo-resistant cancer

Using genome-wide CRISPR technology to identify leukemia's weakness

Using genome-wide CRISPR technology to identify leukemia's weakness

OGT delivers translocation and partial tandem duplication detection with updates to SureSeq NGS portfolio

OGT delivers translocation and partial tandem duplication detection with updates to SureSeq NGS portfolio