Acute Myeloid Leukemia News and Research

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Acute Myeloid Leukemia (AML) is a rapidly progressing cancer of the blood characterized by the uncontrolled proliferation of immature blast cells in the bone marrow. The Leukemia and Lymphoma Society estimates that over 13,000 new cases of AML were diagnosed and approximately 9,000 deaths from AML occurred in the U.S. during 2007. AML is generally a disease of older adults, and the median age of a patient diagnosed with AML is about 67 years. A majority of elderly patients are not considered candidates for standard induction therapy or decline therapy, resulting in an acute need for new treatment options.
Researchers discover metabolic vulnerability in cancer cells with mutated spliceosomes

Researchers discover metabolic vulnerability in cancer cells with mutated spliceosomes

Two cell mutations contribute to the development of acute myeloid leukemia

Two cell mutations contribute to the development of acute myeloid leukemia

Study reveals molecular mechanism of cancer malignancy and development of leukemia

Study reveals molecular mechanism of cancer malignancy and development of leukemia

Newly synthesized anticancer compound can block cancer signaling mechanism

Newly synthesized anticancer compound can block cancer signaling mechanism

Discovery of combination protein leads to first-in-human clinical trial for leukemia

Discovery of combination protein leads to first-in-human clinical trial for leukemia

5 million gift will help create Edward P. Evans Center for MDS at Dana-Farber

5 million gift will help create Edward P. Evans Center for MDS at Dana-Farber

Leukemia is not just one disease

Leukemia is not just one disease

Researchers find a weak spot in cancer cells

Researchers find a weak spot in cancer cells

Cancer stem cells elude the body's immune cells by deactivating danger detector

Cancer stem cells elude the body's immune cells by deactivating danger detector

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

Researchers identify why lymphoma patients may become resistant to specific drug

Researchers identify why lymphoma patients may become resistant to specific drug

Small molecule drug may help overcome ibrutinib resistance in mantle cell lymphona

Small molecule drug may help overcome ibrutinib resistance in mantle cell lymphona

New findings about aggressive blood cancer may help develop drugs with less harmful side effects

New findings about aggressive blood cancer may help develop drugs with less harmful side effects

Overlooked part of cell’s internal machinery may hold key to treating acute myeloid leukemia

Overlooked part of cell’s internal machinery may hold key to treating acute myeloid leukemia

CRISPR-scanning could lead to more effective treatments for cancer

CRISPR-scanning could lead to more effective treatments for cancer

Research reveals genomic basis of acute erythroid leukemia

Research reveals genomic basis of acute erythroid leukemia

New Australian drug trial achieves remarkable results in patients with acute myeloid leukemia

New Australian drug trial achieves remarkable results in patients with acute myeloid leukemia

Scientists find highly promising therapeutic target for leukemia

Scientists find highly promising therapeutic target for leukemia

Study discovers new therapy for aggressive blood cancer

Study discovers new therapy for aggressive blood cancer