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America’s obesity epidemic threatens effectiveness of any COVID vaccine

For a world crippled by the coronavirus, salvation hinges on a vaccine.

6 Aug 2020

Researchers discover how to activate brown fat in humans

The receptor responsible for activating the energy-burning property of brown fat in humans has been identified.

5 Aug 2020

Lower BMI does not protect smokers from fat-associated health risks, shows study

Some smokers might rationalize continuing to smoke because of lower body weight often associated with the habit.

28 Jul 2020

Novel cell-based approach used to reverse age-related impairments in animal model

Elderly people are more prone to infectious diseases as the function of their immune system continuously declines with progression of age.

6 Jul 2020

Study: Oats and rye brans reduce weight gain, hepatic inflammation

In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

2 Jul 2020

BMI should be assessed in management of COVID-19 patients

A new study published on the preprint server medRxiv* in June 2020 reports that obesity is a risk factor of composite poor outcome of COVID-19 disease. On the other hand, COVID-19 patients with 'composite poor outcome' have higher BMI. Therefore, BMI should be assessed in the management of COVID-19 patients, and special attention should be given to patients with obesity.

1 Jul 2020

Novel vaccine that removes aged immune cells mitigates metabolic disorders in obese mice

Aging is a multifaceted process that affects our bodies in many ways. In a new study, researchers from Osaka University developed a novel vaccine that removes aged immune cells and then demonstrated an improvement of diabetes-associated metabolic derangements by vaccinating obese mice.

30 Jun 2020

Sugar consumption is linked with larger fat deposits around the heart, abdomen

Sugar consumption is linked with larger fat deposits around the heart and in the abdomen, which are risky for health.

29 Jun 2020

Researchers discover receptor that makes mice strong and slim

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects.

25 Jun 2020

Study provides novel insights into how fat cells reduce lipid metabolism with age

Knowledge of how human fat tissue is affected by age has long been defined by numerous mouse-based studies.

25 Jun 2020

COVID-19 could trigger diabetes in healthy people

The coronavirus disease (COVID-19) causes severe illness in people with underlying health conditions, such as heart disease, hypertension, lung illness, and diabetes. Now, scientists warn that viral infection may trigger the development of diabetes in healthy people.

18 Jun 2020

Research team provides new insights on the communication between liver and brain

A research team in Vienna is investigating how calorie intake, liver activity and fat storage interact and what role the central nervous system plays in this.

10 Jun 2020

Detachable microneedle depots deliver therapeutic stem cells to injured tissue sites

Mesenchymal stem cells (MSCs) are multipotent in that they naturally replenish the cell types that build our bone, cartilage and adipose tissues.

10 Jun 2020

Study offers potential targets for treating people with Ehlers-Danlos syndrome

Researchers have discovered that a defective form of the protein aortic carboxypeptidase-like protein (ACLP) from patients with Ehlers-Danlos syndrome (EDS) is retained in cells and induces cellular stress.

4 Jun 2020

Study reveals how a fat cell's immune response worsens obesity

When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response--potentially placing people at higher risk of poor outcomes from a variety of diseases and infections, including COVID-19.

2 Jun 2020

Stem cell treatments elicit full structural regeneration of the sun-aged skin

For a while now, some plastic surgeons have been using stem cells to treat aging, sun-damaged skin. But while they've been getting good results, it's been unclear exactly how these treatments - using adult stem cells harvested from the patient's own body - work to rejuvenate "photoaged" facial skin.

28 May 2020

Smokers at increased risk of severe COVID-19 according to a large population study

A new UK study available on the preprint server medRxiv screened 2.4 million users of a symptom reporting application during the coronavirus disease (COVID-19) pandemic, revealing that smokers are at higher risk of increased symptom burden and more prone to hospitalization.

24 May 2020

Study reveals mechanism involved in the development of diabetes, fatty liver

A research group including Professor OGAWA Wataru (Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine) and Project Associate Professor HOSOOKA Tetsuya (Division of Development of Advanced Therapy for Metabolic Disease, Kobe University Graduate School of Medicine) has clarified the mechanism underlying the development of diabetes and non-alcoholic steatohepatitis (NASH), a severe form of fatty liver.

22 May 2020

Does abdominal fat affect COVID-19 outcomes?

As the COVID-19 pandemic seems to be slowing down in some parts of the world slightly but accelerating in others, scientists are investigating the role played by a host of factors that might impact the final outcome. A new study published on the preprint server medRxiv* in May 2020 examines the role of abdominal fat (visceral obesity, VO) in severe COVID-19.

21 May 2020

Diagnosis and treatment of nonalcoholic fatty liver disease

Gastroenterology, the official journal of the American Gastroenterological Association (AGA), has released a special issue providing clinicians and researchers an up-to-date resource on the risk factors, natural history, diagnosis and treatment of nonalcoholic fatty liver disease (NAFLD).

20 May 2020