Airway Inflammation News and Research

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OX40 molecule responsible for airway inflammation in the lungs

A research team led by Xian Chang Li, MD, PhD, Brigham and Women's Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult T helper cells.

30 Jul 2012

AstraZeneca, Rigel enter global license agreement for R256 inhaled JAK inhibitor to treat chronic asthma

AstraZeneca and Rigel Pharmaceuticals Inc. today announced an exclusive worldwide license agreement for the global development and commercialization of R256, Rigel's inhaled JAK inhibitor shown to inhibit IL-13 and IL-4 signalling, which is being investigated as a treatment for moderate to severe chronic asthma. In preclinical research, R256 has been shown to reduce airway inflammation and improve lung function.

19 Jun 2012

Aerocrine’s NIOX MINO and the test kits receive Australian marketing approval

Aerocrine AB announces that its airway inflammation monitor, NIOX MINO, and the NIOX MINO Test Kit, have received marketing approval for the Australian market.

24 May 2012

Airway inflammation linked with asthma-related mortality rates in older adults

Higher mortality rates among older adult asthma patients compared to their younger counterparts may be due, at least in part, to an increase in airway inflammation, according to a study conducted by researchers in Canada, who note that their results imply that elderly patients are either less likely to follow asthma medication dosing instructions, or that the underlying airway inflammation in elderly patients is relatively resistant to current anti-inflammatory therapies.

22 May 2012

Bedfont Scientific Ltd Agree the acquisition of Logan Research Ltd

Bedfont has agreed the acquisition of Logan Research Ltd in a deal to move the company into a new area of scientific applications for breath research.

From Bedfont® Scientific Ltd 25 Apr 2012

ACAAI/AAAAI publish position statement in support of ATS guideline on Aerocrine's FeNO test

Aerocrine AB announces that a nine-member council representing both prestigious asthma societies, the American Academy and the American College of Allergy, Asthma and Immunology (ACAAI and AAAAI), have published a position statement in support of the clinical practice guideline on Aerocrine's FeNO test as published by the ATS.

2 Apr 2012

Local air pollution may explain neighborhood differences in rates of childhood asthma

Where a child lives can greatly affect his or her risk for asthma. According to a new study by scientists at Columbia University, neighborhood differences in rates of childhood asthma may be explained by varying levels of air pollution from trucks and residential heating oil. Results appear online in the Journal of Exposure Science and Environmental Epidemiology.

28 Mar 2012

Commensal bacteria may play an important role in influencing and controlling allergic inflammation

When poet Walt Whitman wrote that we "contain multitudes," he was speaking metaphorically, but he was correct in the literal sense. Every human being carries over 100 trillion individual bacterial cells within the intestine -- ten times more cells than comprise the body itself.

26 Mar 2012

BC BS of Florida retires negative medical policy for FeNO testing

Aerocrine AB announces that BlueCross BlueShield (BC BS) of Florida1 has retired/archived their negative medical policy for FeNO testing. The change is effective March 15, 2012.

17 Mar 2012

UHC retires negative coverage policy effective April 1, 2012

Aerocrine AB announces that United Healthcare has retired its negative coverage policy effective April 1, 2012.

12 Mar 2012

Aerocrine net sales increase 10% to SEK 93.5m for January - December 2011

Aerocrine: January - December 2011. Global Net sales grew by 10% to SEK 93.5m (84.7). Adjusted for currency fluctuations, net sales rose by 18%.

24 Feb 2012

Certain strains of P. aeruginosa cause WBCs to produce high levels of histamine

Could some cases of asthma actually be caused by an allergic reaction to a common environmental bacteria? New research findings published in the Journal of Leukocyte Biology suggests that this idea may not be as far-fetched as it seems. In a research report appearing in the February 2012 print issue, researchers show a link between common environmental bacteria and airway inflammation.

1 Feb 2012

LCI feasible, sensitive non-invasive marker of early lung disease in young children with CF

The lung clearance index (LCI) is a sensitive non-invasive marker of early lung disease in young children with cystic fibrosis (CF), according to a new study from Australian researchers.

27 Jan 2012

HRF inhibitors may provide new therapeutic avenue for treatment of asthma and allergies

La Jolla Institute for Allergy & Immunology scientists have identified the histamine releasing factor (HRF) molecule as a promising target for developing new treatments for a number of allergic reactions including asthma.

3 Dec 2011

Home visits, mobile clinics do not improve asthma outcomes in children

A new Johns Hopkins Children's Center study of Baltimore City children with asthma shows that two programs designed to improve disease outcomes among those who may be affected the worst fall short of expectations.

30 Nov 2011

Laminar air flow therapy via novel device could be beneficial for asthmatics: Study

A new device that offers drug-free bedside filtered air flow can significantly reduce patients' symptoms such as wheezing and tight chests in asthmatics. The temperature controlled laminar airflow treatment, called Protexo, filters out airborne triggers such as dust particles and mites, pet hairs and powders that cause irritation and inflammation of the lungs.

27 Nov 2011

Airway Inflammation News and Research

OX40 molecule responsible for airway inflammation in the lungs

AstraZeneca, Rigel enter global license agreement for R256 inhaled JAK inhibitor to treat chronic asthma

Aerocrine’s NIOX MINO and the test kits receive Australian marketing approval

Airway inflammation linked with asthma-related mortality rates in older adults

Bedfont Scientific Ltd Agree the acquisition of Logan Research Ltd

ACAAI/AAAAI publish position statement in support of ATS guideline on Aerocrine's FeNO test

Local air pollution may explain neighborhood differences in rates of childhood asthma

Commensal bacteria may play an important role in influencing and controlling allergic inflammation

BC BS of Florida retires negative medical policy for FeNO testing

UHC retires negative coverage policy effective April 1, 2012

Aerocrine net sales increase 10% to SEK 93.5m for January - December 2011

Certain strains of P. aeruginosa cause WBCs to produce high levels of histamine

LCI feasible, sensitive non-invasive marker of early lung disease in young children with CF

HRF inhibitors may provide new therapeutic avenue for treatment of asthma and allergies

Home visits, mobile clinics do not improve asthma outcomes in children

Laminar air flow therapy via novel device could be beneficial for asthmatics: Study

Nocturnal temperature controlled laminar airflow treatment for atopic asthma

Research demonstrates negative impact of smoking even one cigarette in young people

New insight into how emphysema and COPD develop

Three key steps to prevent asthma attacks in children during winter

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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