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Researchers identify novel genetic mutations linked to hereditary diffuse gastric cancer

Researchers have identified novel genetic mutations that are linked to hereditary diffuse gastric cancer, with these mutations being due to both independent mutational events and common ancestry, according to a study in the June 6 issue of JAMA.

5 Jun 2007

Genetic risk for early death in rheumatoid arthritis

A chronic autoimmune disease, rheumatoid arthritis (RA) is marked by inflammation that takes a progressive toll on not only the joints, but also various organs and the whole body.

30 Apr 2007

Variations of two common genes associated with progression to more advanced forms of age-related macular degeneration

Age-related macular degeneration (AMD; when the center of the inner lining of the eye suffers thinning, atrophy, and in some cases bleeding), which can lead to visual impairment and legal blindness, is associated with variations in the genes CFH and LOC387715.

25 Apr 2007

People with two copies of a particular gene have a 70% higher risk of being obese

Scientists have identified the most clear genetic link yet to obesity in the general population as part of a major study of diseases funded by the Wellcome Trust, the UK's largest medical research charity.

15 Apr 2007

Study identifies clearest link yet to obesity risk

12 Apr 2007

Genetic mutation that prevents sperm production found

Up to 15 percent of couples of childbearing age struggle with the heartache of infertility.

11 Apr 2007

Shyness, genetics and parents

New research from the Child Development Laboratory at the University of Maryland shows that shyness in kids could relate to the manner in which a stress-related gene in children interacts with being raised by stressed-out parents.

5 Mar 2007

Apolipoprotein E gene raises newborns' cerebral palsy risk

Apolipoprotein E (APOE), a gene associated with heightened risk for Alzheimer's disease in adults, can also increase the likelihood that brain-injured newborns will develop cerebral palsy, researchers at Children's Memorial Research Center have discovered.

5 Feb 2007

Eye color reflects a simple, predictable and reliable genetic pattern of inheritance

Before you request a paternity test, spend a few minutes looking at your child's eye color. It may just give you the answer you're looking for.

23 Oct 2006

Juice lowers Alzheimer's risk

In a large epidemiological study, researchers found that people who drank three or more servings of fruit and vegetable juices per week had a 76 percent lower risk of developing Alzheimer's disease than those who drank juice less than once per week.

4 Sep 2006

Variation in 3 genes influences risk of age-related macular degeneration

Researchers in Boston have discovered a new common, noncoding variant in the Complement Factor H (CFH) gene that is associated with age-related macular degeneration (AMD), the leading cause of irreversible visual impairment and blindness among persons aged 60 and older.

30 Aug 2006

Gene variant increases risk of type 2 diabetes - but healthy lifestyle changes reduce genetic risk

Researchers have confirmed that a gene variant confers susceptibility to type 2 diabetes in participants of the Diabetes Prevention Program (DPP), a large clinical trial in adults at increased risk for developing type 2 diabetes.

21 Jul 2006

Donepezil slows brain shrinkage in some patients with mild cognitive impairment

According to a new study, the drug donepezil measurably slows the rate of brain shrinkage in some patients with mild cognitive impairment, a pre-Alzheimer's disease condition. The shrinkage was measured by magnetic resonance imaging (MRI).

18 Jul 2006

New genetic clue discovered about breast cancer

New research has discovered that women in Iceland with a particular gene that raises the risk of breast cancer were virtually certain to develop the disease if they also had a mutation in another gene.

20 Jun 2006

Common genetic prostate cancer variant identified

Prostate cancer (CaP) is a presumed result of both genetic and environmental events.

19 Jun 2006

Nepalese Rhesus monkeys may provide new alternative for HIV/AIDS research

Rhesus monkeys in Nepal may provide a suitable alternative to alleviate a critical shortage of laboratory animals used in work to develop vaccines against diseases such as HIV/AIDS.

1 Jun 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Gene silencing protein discovered

A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off -in this case, the turning off of thousands of nearly identical genes in a hybrid plant.

8 May 2006

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

The discovery of a gene, called PRDM1, as a tumor suppressor sheds new light on the cause - and possible treatment - of diffuse large B-cell lymphomas (DLBCLs), a cancer of the blood's B-lymphocytes. DLBCLs comprise about 30 percent of non-Hodgkin's lymphomas.

25 Apr 2006

Environmental scientists identify new culprits in the cancer equation

In the granite-rich region of Western North Carolina, taking a daily shower could pose a risk of developing lung cancer. So could working from home every day. That's because granite emits a carcinogenic gas, radon.

13 Apr 2006