Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

UVA Alzheimer's study pinpoints how tau protein damages brain cells

University of Virginia Alzheimer's researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.

20 Dec 2023

Use of blood fat-lowering statins linked to slower progression of Alzheimer's dementia

Blood fat-lowering statins could slow the progression of Alzheimer's disease, at least for some patients. This is the result of a new study led by Karolinska Institutet published in Alzheimer Research and Therapy.

19 Dec 2023

NEMO protein's crucial role in Parkinson's defense revealed

Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson’s disease.

19 Dec 2023

Common heart medication causes false positives on Alzheimer's blood test

Researchers from the University of Gothenburg, in collaboration with colleagues from University of Glasgow, present data that the drug Entresto (sacubitril/valsartan) which is commonly used for the treatment of cardiac failure leads to a marked reduction in plasma Aβ ratio, a candidate blood test for Alzheimer's disease (AD).

18 Dec 2023

Study reveals altered time perception in early Alzheimer's stages, offering potential early diagnostic marker

Study investigates time perception in Alzheimer's disease and its preclinical stage, subjective cognitive decline (SCD), revealing specific alterations in temporal processing that could be early markers of cognitive decline.

18 Dec 2023

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023 Breakthrough of The Year.

15 Dec 2023

Alzheimer's may worsen COVID-19 outcomes via olfactory mucosa changes

A new study identifies alterations in the transcriptomic signatures in human olfactory mucosal cells of individuals with Alzheimer's disease following SARS-CoV-2 infection, potentially contributing to exacerbated COVID-19 outcomes.

15 Dec 2023

Physical and social activities may hold the secret to sharper memories in old age

Physical and social activities in old age have a protective effect on the entorhinal cortex, researchers at UZH have shown.

14 Dec 2023

Understanding how proteasome dysfunction contributes to age-related cognitive decline

About 40 percent of people over age 65 suffer some form of age-related memory loss, which puts them at higher risk for developing dementia and Alzheimer's disease.

13 Dec 2023

People with very irregular sleep patterns may have higher dementia risk

People who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns, according to new research published in the December 13, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Dec 2023

Idiopathic hypersomnia may not be as rare as previously thought

People who are very sleepy during the day, despite a good night's rest, may have a sleep disorder called idiopathic hypersomnia. New research has found this neurologic disorder may not be as rare as once thought.

13 Dec 2023

Study reveals a fascinating link between regular exercise and better brain health

A fascinating link between regular exercise and better brain health has been revealed, according to an international study that included a team of clinical researchers from Pacific Neuroscience Institute's Brain Health Center, located at Providence Saint John's Health Center.

13 Dec 2023

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis.

12 Dec 2023

Colombian family's Alzheimer's anomaly offers insights into disease pathogenesis and prevention

Alzheimer's disease has plagued one large Colombian family for generations, striking down half of its members in the prime of life.

11 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

Researchers develop novel exosome-based drug delivery system to treat Alzheimer's disease

A research team led by Hong Kong Baptist University (HKBU) has developed a novel drug delivery system for Alzheimer’s disease (AD).

11 Dec 2023

Is your body out of sync? Study finds organs age at varying rates

Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.

7 Dec 2023

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Researchers performed a proteomic analysis to identify serologic indicators of organ aging and disease.

7 Dec 2023

Military personnel repeatedly exposed to blasts show increased brain inflammation and structural changes

The brains of special warfare community personnel repeatedly exposed to blasts show increased inflammation and structural changes compared with a control group, potentially increasing the risk of long-term, brain-related disease, according to a new study.

6 Dec 2023

Twice daily electrical stimulation boosts brain plasticity and improves memory in Alzheimer's patients

Twice daily non-invasive electrical stimulation of the brain may boost mental processes (cognitive function) in people with Alzheimer's disease, suggest the results of a small clinical trial published online in the open access journal General Psychiatry.

6 Dec 2023

Alzheimer's Disease News and Research

Further Reading

UVA Alzheimer's study pinpoints how tau protein damages brain cells

Use of blood fat-lowering statins linked to slower progression of Alzheimer's dementia

NEMO protein's crucial role in Parkinson's defense revealed

Common heart medication causes false positives on Alzheimer's blood test

Study reveals altered time perception in early Alzheimer's stages, offering potential early diagnostic marker

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Alzheimer's may worsen COVID-19 outcomes via olfactory mucosa changes

Physical and social activities may hold the secret to sharper memories in old age

Understanding how proteasome dysfunction contributes to age-related cognitive decline

People with very irregular sleep patterns may have higher dementia risk

Idiopathic hypersomnia may not be as rare as previously thought

Study reveals a fascinating link between regular exercise and better brain health

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

Colombian family's Alzheimer's anomaly offers insights into disease pathogenesis and prevention

MIT scientists develop nanoparticles to reduce inflammation in the brain

Researchers develop novel exosome-based drug delivery system to treat Alzheimer's disease

Is your body out of sync? Study finds organs age at varying rates

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Military personnel repeatedly exposed to blasts show increased brain inflammation and structural changes

Twice daily electrical stimulation boosts brain plasticity and improves memory in Alzheimer's patients

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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