Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Gene deletion may make you smarter: Study

A new study has shown that switching off a single gene in mice unlocks a part of their brain that is otherwise inactive, boosting learning and memory. Considering the fact that humans have a similar gene, this sparks hope for many especially those who suffer from dementia and Alzheimer’s.

20 Sep 2010

New findings in brain plasticity and development

Brain plasticity – the brain’s ability to reorganise neural pathways – will be discussed at a major symposium this week at the University of New South Wales (Friday 24 September).

19 Sep 2010

Caregiver Expo2010 to be held in November in conjunction with National Family Caregiver Month

The Caregiver Expo2010, presented by Alternatives for Seniors, will be held 9:30 a.m. to 3 p.m. Saturday, November 13, 2010 at the Doubletree Hotel, in Oak Brook, Illinois. The free event is being held in conjunction with the National Family Caregiver Month observed every November. National Family Caregiver Month is a nationally recognized time to focus attention on the more than 65 million family caregivers who provide 80% of our nation's long term care services.

18 Sep 2010

Ligand Pharmaceuticals transfers license rights to Proximagen for CXCR4 target

Ligand Pharmaceuticals Incorporated announced today that it has transferred exclusive license rights to Proximagen Limited for a series of compound hits related to the CXCR4 target with application for a number of indications including those related to the central nervous system. Ligand will receive an upfront payment and continue to be entitled to receive potential future milestone and royalty payments.

18 Sep 2010

FDA accepts to review Aricept NDA for Alzheimer's disease

Teikoku Pharma USA, Inc., an international specialty pharmaceutical company, announced today that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for a new weekly transdermal patch of Aricept, a leading medication for the treatment of Alzheimer's disease.

18 Sep 2010

Transition stops TT-223 gastrin analogue combination clinical study in type 2 diabetes

Transition Therapeutics Inc. announced today that a clinical study of gastrin analogue TT-223 in combination with a Lilly proprietary GLP-1 analogue in patients with type 2 diabetes did not meet its efficacy endpoints. Given these findings, there will be no further development of TT-223.

17 Sep 2010

Common Alzheimer's disease drug enhances learning of new skills

Research on a drug commonly prescribed to Alzheimer's disease patients is helping neuroscientists at the University of California, Berkeley, better understand perceptual learning in healthy adults.

17 Sep 2010

Research on BMP6 protein suggests potential therapeutic target for Alzheimer's disease

Elevated levels of a growth protein in the brains of Alzheimer's disease (AD) patients is linked to impaired neurogenesis, the process by which new neurons are generated, say researchers at the University of California, San Diego in today's edition of The Journal of Neuroscience.

17 Sep 2010

Alzheimer Society, Coffee Break commits to support Canadians living with Alzheimer's disease

Today, hundreds of people across the nation have made the commitment to make their "coffee count" and are drinking a cup of coffee to raise funds in support of Canadians living with Alzheimer's disease or a related dementia. This marks 15 years' of successful grassroots fundraising by the Alzheimer Society, raising over $12 million in support of essential programs and services for people with dementia, their families and caregivers.

16 Sep 2010

Same brain lesions associated with dementia responsible for mild memory loss in old age

New research suggests that old age may not play a role in why older people become forgetful. According to a study published in the September 15, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology, the same brain lesions that are associated with dementia are responsible for mild memory loss in old age.

16 Sep 2010

New clinical trial supports benefits of turmeric extract to people with osteoarthritis

A new clinical trial supports the benefits to people with osteoarthritis who used a unique extract of turmeric. Scientists in Italy have studied the pain-relief, increased flexibility, and other effects of a special, patented extract of the roots of turmeric, the flavorful spice that has been used for centuries as a traditional remedy. Turmeric formulations have shown a wide range of safety and significant scientific and clinical benefits in recent animal research and human clinical trials.

16 Sep 2010

Mild memory loss can indicate progressive dementia: Research

Simply getting older is not the cause of mild memory lapses often called senior moments, according to a new study by researchers at the Rush Alzheimer's Disease Center. The study, published in the September 15, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology, found that even the very early mild changes in memory that are much more common in old age than dementia are caused by the same brain lesions associated with Alzheimer's disease and other dementias.

16 Sep 2010

COTI selected for Canadian life sciences partnering mission

Critical Outcome Technologies Inc. announced today that the Company was selected by the Consulate General of Canada and BIOTECanada to attend a life sciences partnering mission in Boston, MA. This initiative is being held in conjunction with the BioPharm America conference taking place September 15-17, 2010.

15 Sep 2010

Study on spinal cord stem cells paves way for post stroke symptom treatment

Neuralstem, Inc. announced that its spinal cord stem cells survived in rat brains affected by stroke and differentiated predominantly into neurons. The transplanted animals showed significant improvement in some motor skill and strength measurements. The study entitled, "Intracerebral Implantation of Adherent Human Neural Stem Cells To Reverse Motor Deficits in Chronic Stroke Rats," was presented earlier today by senior study author, Dr. Shinn-Zong Lin, M.D., Ph.D., at the Stem Cells USA & Regenerative Medicine Conference

15 Sep 2010

Stemedica Cell Technologies completes master bank of mesenchymal bone marrow-derived stem cells

Stemedica Cell Technologies, Inc., a world leader in adult stem cell manufacturing and research, announced today that it has completed its proprietary master bank of mesenchymal bone marrow-derived stem cells.

14 Sep 2010

AstraZeneca Chief Scientist shares enthusiasm for collaborative clinical research

The pharmaceutical industry must ensure an improved record of delivery by providing high quality, cost effective solutions to well defined unmet needs. This can be achieved through strategic collaborations that strengthen disease knowledge and provide improved tools to strengthen therapeutic target validation and to monitor therapeutic efficacy, says Andy Dray, Chief Scientist at AstraZeneca.

14 Sep 2010

Metabolon receives patent for metabolic age analysis

Metabolon, Inc., leaders in global metabolomics, biomarker discovery and biochemical analysis, announced today the grant of US Patent 7,781,160 entitled "Biomarkers Related to Metabolic Age and Methods Using the Same". The USPTO awarded the patent to Metabolon on August 24, 2010. This is the 12th patent issued to Metabolon.

14 Sep 2010

Structural component inside neurons dances when connections are strengthened

Scientists at Emory University School of Medicine have uncovered how a structural component inside neurons performs two coordinated dance moves when the connections between neurons are strengthened.

14 Sep 2010

Researchers to discuss brain's secrets at neuroscience conference

Top brain researchers from around the world will be in Milwaukee, Sept, 16-19, 2010, for a neuroscience conference focused on gaining insights into the brain's inner workings to better understand how the brain thinks, how the brain develops, and how the brain is altered by neurological diseases and how it responds to treatment.

14 Sep 2010

Researchers identify novel molecular pathway of Parkinson’s disease

A new study led by researchers at Columbia University Medical Center has identified a novel molecular pathway underlying Parkinson's disease and points to existing drugs which may be able to slow progression of the disease.

14 Sep 2010

Alzheimer's Disease News and Research

Further Reading

Gene deletion may make you smarter: Study

New findings in brain plasticity and development

Caregiver Expo2010 to be held in November in conjunction with National Family Caregiver Month

Ligand Pharmaceuticals transfers license rights to Proximagen for CXCR4 target

FDA accepts to review Aricept NDA for Alzheimer's disease

Transition stops TT-223 gastrin analogue combination clinical study in type 2 diabetes

Common Alzheimer's disease drug enhances learning of new skills

Research on BMP6 protein suggests potential therapeutic target for Alzheimer's disease

Alzheimer Society, Coffee Break commits to support Canadians living with Alzheimer's disease

Same brain lesions associated with dementia responsible for mild memory loss in old age

New clinical trial supports benefits of turmeric extract to people with osteoarthritis

Mild memory loss can indicate progressive dementia: Research

COTI selected for Canadian life sciences partnering mission

Study on spinal cord stem cells paves way for post stroke symptom treatment

Stemedica Cell Technologies completes master bank of mesenchymal bone marrow-derived stem cells

AstraZeneca Chief Scientist shares enthusiasm for collaborative clinical research

Metabolon receives patent for metabolic age analysis

Structural component inside neurons dances when connections are strengthened

Researchers to discuss brain's secrets at neuroscience conference

Researchers identify novel molecular pathway of Parkinson’s disease

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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