Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Novel tool helps study the biochemical basis of Alzheimer's

A new study being published in this Friday's online edition of Cell will help answer the question, what causes Parkinson's disease?

12 Nov 2008

Researchers uncover beneficial mechanism of the helpful "Dr. Jekyll" side of the Cdk5 protein

Researchers at UT Southwestern Medical Center have uncovered new insights into the "Dr. Jekyll and Mr. Hyde" nature of a protein that stimulates stem-cell maturation in the brain but, paradoxically, can also lead to nerve-cell damage.

12 Nov 2008

All stem cells are not created equal, explains expert

During the course of the Presidential campaign, Obama signaled his intention to reverse Bush's controversial limit on federal funding of embryonic stem cell research.

11 Nov 2008

Raptor Pharmaceuticals announces positive results for Convivia program

Raptor Pharmaceuticals Corp. has announced positive results in its Phase IIa study of oral 4-methylpyrazole ("4-MP") in subjects with ALDH2 deficiency, or ethanol intolerance, as the initial development stage of its Convivia program.

11 Nov 2008

Protein can nurture or devastate brain cells, depending on its 'friends,' UT Southwestern researchers find

11 Nov 2008

Discovery of mechanism that regulates the development of stem cells into neurons

Researchers at the University of Southern California (USC) have identified a novel mechanism in the regulation and differentiation of neural stem cells.

11 Nov 2008

Researchers describe how cells recycle protein waste

Garbage collectors are important for removing trash; without them waste accumulates and can quickly become a health hazard.

11 Nov 2008

Education delays onset of the dementia

A test that reveals brain changes believed to be at the heart of Alzheimer's disease has bolstered the theory that education can delay the onset of the dementia and cognitive decline that are characteristic of the disorder.

10 Nov 2008

Greater thinking, learning and memory abilities delay symptoms of Alzheimer's disease

Individuals with higher education levels appear to score higher on cognitive tests despite having evidence of brain plaques associated with Alzheimer's disease, according to a report in the November issue of Archives of Neurology , one of the JAMA/Archives journals.

10 Nov 2008

Education lessens the effects of Alzheimer's

The scientists from the Washington University School of Medicine, St. Louis, say their research supports the 'cognitive reserve' hypothesis and individuals with levels of higher education levels score higher on cognitive tests despite having Alzheimer's disease.

10 Nov 2008

Study finds 25% of family caregivers of AD patients go to ER or are hospitalized

One quarter of all family caregivers of Alzheimer's disease patients succumb to the stress of providing care to a loved one and become hospital patients themselves, according to an Indiana University study published in the November 2008 issue of the Journal of General Internal Medicine.

10 Nov 2008

Grape seeds could ward off Alzheimer's

Australian scientists are suggesting that grape seeds may be a potential treatment in warding off Alzheimer's disease.

10 Nov 2008

Simple brain mechanisms explain arbitrary human visual decisions

Mark Twain, a skeptic of the idea of free will, argues in his essay "What Is Man?" that humans do not command their minds or the opinions they form.

10 Nov 2008

Australian-led global initiative to improve diagnosis of genetic disorders

An Australian-led global initiative to improve the diagnosis of genetic disorders and reduce errors in the reporting of genetic variations has been published today in the prestigious scientific journal Science.

7 Nov 2008

Variations in gene pathway alter risk of esophageal cancer

Variations in a common gene pathway may affect esophageal cancer risk, a dangerous and rapidly increasing type of cancer, according to research by scientists at The University of Texas M. D. Anderson Cancer Center.

6 Nov 2008

Nicotinamide, a form of vitamin B3, reduces Alzheimer's symptoms

An over-the-counter vitamin in high doses prevented memory loss in mice with Alzheimer's disease, and UC Irvine scientists now are conducting a clinical trial to determine its effect in humans.

5 Nov 2008

Alzheimer's + diabetes + high blood pressure = a shorter life

A study has found that people with Alzheimer's disease who also suffer from diabetes and high blood pressure may die earlier.

4 Nov 2008

Diabetes and high blood pressure shorten lifespan in Alzheimer's disease

People with Alzheimer's disease who also have diabetes or high blood pressure may die sooner than people without such disorders, according to a study published in the November 4, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2008

Pulsed ultrasound used to remote control brain circuits

In a twist on nontraditional uses of ultrasound, a group of neuroscientists at Arizona State University has developed pulsed ultrasound techniques that can remotely stimulate brain circuit activity.

29 Oct 2008