Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New AF267B drug reverses key cognitive deficits, pathology in Alzheimer's

A new drug that enhances the activity of a key brain cell receptor involved in Alzheimer's disease (AD) reverses learning and memory deficits in mice engineered to have pathological hallmarks of the disease.

13 Mar 2006

New test for detecting small amounts of proteins in the blood

Researchers at the University of Pennsylvania School of Medicine have developed a paradigm-shifting method for detecting small amounts of proteins in the blood.

13 Mar 2006

ATF2 protein may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment

Researchers at Purdue University have discovered a molecular mechanism that may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment and that also may be involved in Alzheimer's and heart disease.

9 Mar 2006

Depressed older adults more likely to develop mild cognitive impairment

Older adults with depressive symptoms are more likely than those without depression to develop mild cognitive impairment (MCI) within six years, according to a study conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

9 Mar 2006

Major biomarker candidates for Alzheimer's disease explored

Alzheimer's disease - specific biomarkers clearly are needed for the differential diagnosis of cognitive impairment in the elderly.

8 Mar 2006

Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Genes play a key role in stress response

Both nature and nurture - genetic makeup and the environment experienced through life - combine to influence health and well-being, Duke University Medical Center researchers and their colleagues have determined in four new studies.

7 Mar 2006

Better tests needed for fuller view of head injuries

Concussion patients with a normal head CT scan may believe they are free of brain injury, but CT scans often miss damage at the molecular level, warns a University of Rochester Medical Center study.

1 Mar 2006

Cell-death mechanism linked to developmental and degenerative brain disorders

Conclusive evidence that neurodevelopmental disorders such as mental retardation and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and ataxias can be caused, at least in part, by specific gene defects that interfere with the electrical impulses of rapid-firing brain nerve cells called bursting neurons.

1 Mar 2006

Effects of stress on the brain could trigger Alzheimer's

Researchers at the University of Edinburgh have identified for the first time a certain area of the brain which can shrink in old age and cause depression and Alzheimer's disease.

1 Mar 2006

Spinocerebellar ataxia and other neurodegenerative diseases might be treatable with drugs that alter the activity of potassium channels

For the first time, researchers have linked mutations in a gene that regulates how potassium enters cells to a neurodegenerative disease and to another disorder that causes mental retardation and coordination problems.

27 Feb 2006

Ginkgo biloba reduces aggressive cancer risk in animal experiments

Researchers at Georgetown University Medical Center say they now have a clearer picture of how an extract from the leaves of the Ginkgo biloba tree reduces the risk of aggressive cancer in animal experiments.

27 Feb 2006

Engineers identify tiny iron oxide particles associated with Alzheimer's

Engineers have found a way to pinpoint and identify the tiny iron oxide particles associated with Alzheimer's and other neurodegenerative diseases in the brain.

27 Feb 2006

Eating seafood still beneficial in many ways

Though some species of fish around the world's are likely to be contaminated with mercury, PCBs and other toxins, the benefits of eating seafood continue to outweigh the risks, a panel of scientists recently said at the annual meeting of the American Association for the Advancement of Science.

27 Feb 2006

Lifestyle choices help maintain our brain and emotional health

Heart health risk factors and lifestyle choices, such as exercise, learning new things and staying socially connected, are associated with maintaining brain health as we age according to a new report.

24 Feb 2006

New report suggests promising strategies to preserve brain health as people grow older

With the rapid aging of the population, the National Institutes of Health (NIH) is intensifying the search for strategies to preserve brain health as people grow older.

24 Feb 2006

Study provides further insight into the molecular control of apoptosis

Researchers at Yale School of Medicine have gained deeper understanding of two members of a family of proteins called caspases that play a key role in promoting apoptosis, a process in which the cell responds to external signals by essentially committing suicide.

23 Feb 2006

We may learn best on an empty stomach!

Researchers at Yale School of Medicine have found evidence that a hormone produced in the stomach directly stimulates the higher brain functions of spatial learning and memory development.

23 Feb 2006

Education and rates of cognitive decline in incident Alzheimer's disease

High levels of education may help ward off Alzheimer's disease, but they also speed up its progression once developed, reveals research in the Journal of Neurology Neurosurgery and Psychiatry.

21 Feb 2006

Tetrabenazine cuts down involuntary movements in Huntington's disease

The medication tetrabenazine cut down involuntary movement in patients with Huntington's disease on average by about 25 percent, with many patients experiencing a greater improvement, according to a study in the February 14 issue of the journal Neurology.

17 Feb 2006