Anaphylaxis News and Research

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Anaphylaxis is an acute multi-system severe type I hypersensitivity reaction. Due in part to the variety of definitions, between 1% and 15% of the population of the United States can be considered "at risk" for having an anaphylactic reaction if they are exposed to one or more allergens. Of those people who actually experience anaphylaxis, up to 1% may die as a result.

Looking for the source: new routes for allergy treatment

A new multinational study has reported a very full account of the B lymphocytes that produce group E antibodies, also called IgE (Immunoglobulin E), that are behind allergic reactions, which are common in up to a third of the world’s population.

26 Nov 2019

Study about cells producing group E antibodies would help fight against allergies

Researchers of Sechenov University together with their colleagues from Russia and Austria summarized everything known about cells producing group E antibodies

25 Nov 2019

New treatment stops peanut allergy for 6 weeks with single dose

A small study published in the journal JCI Insight on November 14, 2019, suggests that antibody treatment could help people with severe allergy to peanuts eat a small amount of peanut-containing food just two weeks later, without any ill effects. This seems to show that this is a safe, fast and effective treatment for food allergy.

14 Nov 2019

New information on benefits of oral food challenges when diagnosing food allergies

Oral food challenges (OFCs) are the gold standard for allergists when diagnosing a food allergy. The person being tested is given a very small dose of the food by mouth under the supervision of a board-certified allergist to test for a severe reaction.

8 Nov 2019

UGA researcher working to correct penicillin allergy misconception

More than 30 million people in the United States wrongly believe they are allergic to penicillin - resulting in millions of dollars in added health care costs, adverse side effects from the use of more powerful antibiotics and a risk in the rise of dangerous antibiotic resistant infections.

29 Oct 2019

Heavier babies more likely to develop childhood allergies

A new study shows that babies who weigh more at any gestational age have a higher risk of later developing food allergies or eczema in childhood. However, there was no increase in the risk of hay fever. The paper published in the Journal of Allergy and Clinical Immunology found that the risk of food allergy went up by 44% and of eczema by 17% for each kilogram of added weight. On the other hand, restricted growth in the womb appears to be protective.

15 Oct 2019

Peripherally inserted central catheters associated with serious allergic reactions in patients

Peripherally inserted central catheters (PICCs) that use a magnetized tip to guide insertion were associated with serious allergic reactions in patients, according to a study published today in Infection Control & Hospital Epidemiology, the journal for the Society for Healthcare Epidemiology of America. Severe adverse reactions occurred in patients within minutes of PICC insertion.

8 Oct 2019

New 'Idiopathic Anaphylaxis Yardstick' offers guidance for diagnosis and treatment

Many people in danger of the severe allergic reaction known as anaphylaxis understand exactly what they need to avoid to stay safe.

18 Sep 2019

Research reveals potential target for therapies to prevent severe allergic reactions

Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure.

2 Aug 2019

New study launched to evaluate experimental treatment for food allergy

Though food allergy affects more than 4.8 million children in the United States, no approved preventative treatments currently exist.

2 Aug 2019

Use of broad-spectrum antibiotics to treat pneumonia does more harm than good

A new study by researchers at Intermountain Healthcare has found that administering broad-spectrum antibiotics, which act against a wide range of disease-causing bacteria, to treat patients with pneumonia often does more harm than good.

31 Jul 2019

Novel vaccine against bee sting allergy successfully tested

A recently completed trial on a bee sting vaccine containing a novel adjuvant called Advax to increase its efficacy has raised hopes that severe allergic reactions, sometimes fatal, to bee venom in allergic people could soon be a thing of the past. The vaccine was designed to neutralize the venom of the European honeybee.

17 Jul 2019

Food allergy caused by absence of beneficial bacteria in the gut

A study by scientists at Boston Children's Hospital and Brigham and Women's Hospital, published today in Nature Medicine, makes a strong case that the national epidemic of food allergy is caused by the absence of certain beneficial bacteria in the human gut.

25 Jun 2019

Treatment guidelines for managing anaphylaxis in children need to be reassessed

Treatment guidelines for managing anaphylaxis in children should be reassessed, according to a new Canadian study published in the Journal of Allergy and Clinical Immunology: In Practice.

31 May 2019

Scientific evidence for and against causal associations for 47 adverse effects after immunization

A new systematic review provides a succinct summary of the scientific evidence for and/or against causal associations for 47 adverse events following immunization.

29 Apr 2019

Peanut allergy tolerance treatment may increase the risk of anaphylaxis

Treating children who have a peanut allergy by gradually exposing them to increasing levels of peanut extract may actually increase their risk of allergic attacks, warn researchers.

26 Apr 2019

Newly identified skin-gut communication helps illuminate link between food allergy and eczema

Scratching the skin triggers a series of immune responses culminating in an increased number of activated mast cells--immune cells involved in allergic reactions--in the small intestine, according to research conducted in mice.

24 Apr 2019

Researchers identify new allergen responsible for allergy to durum wheat

An international team of researchers, in which a female researcher from Universidad Politécnica de Madrid is involved, has identified one of the main causes of food allergy in the Mediterranean area.

22 Apr 2019

New study reveals five facts about allergies to vaccines

There is little chance you are actually allergic to vaccines and, if you are, your allergist can give it to you. Only one in 760,000 vaccinations will respond with anaphylaxis. For all other side effects, there are ways around any problem.

8 Apr 2019

Gut microbiome may help prevent development of cow's milk allergy

New research suggests that the gut microbiome may help prevent the development of cow's milk allergy. Scientists at the University of Chicago found that gut microbes from healthy human infant donors transplanted into mice protected animals exposed to milk from experiencing allergic reactions, while gut microbes transplanted from infants allergic to milk did not.

14 Jan 2019