Angiotensin Converting Enzyme 2 News and Research

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Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

New research describes a novel approach whereby SARS-2 antigens were analyzed for conserved sites that may be targeted by broadly neutralizing antibodies that will confer immunity to other Sarbecoviruses.

10 Mar 2022

Study isolated largest panel of β-CoV broadly neutralizing antibodies to date

Researchers isolated a large panel of broadly neutralizing antibodies from COVID-19 recovered-vaccinated donors.

10 Mar 2022

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

A new study used glycoprotein profiling technology platform that couples high-resolution LC-MS for glycoprotein analysis in regards to COVID-19.

9 Mar 2022

CRIPSR identifies cell-type-specific ACE2 modifiers

Researchers compile a list of candidate genes to identify the surface abundance of functional regulators of ACE2.

9 Mar 2022

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Researchers assessed the diabetogenic potential of SARS-CoV-2 in a single cell in vitro analysis on the pancreatic islet cells.

9 Mar 2022

How will mutations change the SARS-CoV-2 spike protein in the future?

A new Cells review discusses the factors that affect the function of the SARS-CoV-2 S protein and provides theoretical limits of this viral protein.

8 Mar 2022

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A recent study predicted the efficacy of the SOBERANA 02 and SOBERANA Plus COVID-19 vaccines in children.

8 Mar 2022

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

SARS-CoV-2 spike protein characteristics responsible for viral evolution in human hosts

Researchers directly compared the pre-fusion spikes of SARS-CoV-2 Alpha and Beta variants with the original Wuhan strain and the D614G-only variant.

8 Mar 2022

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Researchers developed a vaccine candidate termed Ad26.COV2.S.529, encoding a stabilized Omicron-based S protein resembling ancestral SARS-CoV-2 Wuhan-Hu-1 S protein.

8 Mar 2022

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Researchers presented a technique called rapid in vitro inhibition assay (RIVIA), whereby potential SARS-CoV-2 antibody and nanobody candidates can be rapidly screened.

8 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Angiotensin Converting Enzyme 2 News and Research

Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

Study isolated largest panel of β-CoV broadly neutralizing antibodies to date

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

CRIPSR identifies cell-type-specific ACE2 modifiers

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

How will mutations change the SARS-CoV-2 spike protein in the future?

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 spike protein characteristics responsible for viral evolution in human hosts

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

How have human organoids been used in research to study SARS-CoV-2?

Impact of humoral responses in COVID-19

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Combating COVID cytokine storm with targeted nucleic acid therapies

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Aldosterone levels undetectably low in hospitalized COVID-19 patients

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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