Angiotensin Converting Enzyme 2 News and Research

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Study may help explain how COVID-19 increases stroke risk

A UCLA-led study may help explain how COVID-19 increases the risk for stroke. Scientists made the finding by running fluid spiked with a COVID-19-like protein through a 3D-printed model of the arteries of a patient who had suffered a stroke.

18 Dec 2020

Higher COVID-19 mortality among certain groups in Colombia linked to structural inequalities

Researchers at the Ministry of Health and Social Protection in Bogotá, Colombia, provided evidence of socioeconomic inequalities in COVID-19 deaths in terms of age, sex, ethnicity, type of health insurance regime, and socioeconomic status.

18 Dec 2020

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

A new paper describes the development and validation of a rapid test to measure the neutralizing activity of serum against COVID-19 using a drop of blood.

18 Dec 2020

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

A preprint indicates that SARS-CoV-2 requires cholesterol to accomplish entry into the host cells and membrane fusion.

17 Dec 2020

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

SARS-CoV-2 spike deletion ΔH69/ΔV70 shows repeated emergence and spread

Since the COVID 19 pandemic, it has been established that the causative virus, SARS-CoV-2 gains entry to the target host cell via its spike glycoprotein.

17 Dec 2020

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

Study shows an inflammatory response in the mice brain is responsible for severe COVID-19

Researchers demonstrated that neuroinvasion and encephalitis caused by SARS-CoV-2 is associated with significant mortality in a special mouse model.

17 Dec 2020

Why are some groups more vulnerable to COVID-19?

News-Medical speaks to Dr. Jaswinder Singh about his research surrounding why some groups are more susceptible to severe cases of COVID-19.

17 Dec 2020

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

As researchers continue to search for antivirals to counter COVID-19, a study presents the potential utility of a decoction called Respiratory Detox Shot (RDS).

16 Dec 2020

Neanderthal gene variant increases risk of severe COVID-19

Researchers in Germany have conducted a study showing that between 2 and 8% of people in Eurasia carry a genetic variant inherited from Neanderthals that significantly increases the risk of becoming critically ill with coronavirus disease 2019 (COVID-19).

15 Dec 2020

D614G mutation promotes lysosomal trafficking of SARS-CoV-2 spike protein

In the current COVID-19 pandemic, SARS-CoV-2 has led to millions of infections worldwide, with over 1.5 million deaths.

14 Dec 2020

Distant residues modulate the conformational opening in SARS-CoV-2 spike protein

Scientists present an insight into the RBD dynamics with physically distant residues in the spike protein, elaborating on the importance of predicted mutations for therapeutics.

11 Dec 2020

COVID-19 infection may also affect the central nervous system, cause neurological disorders

COVID-19 is known primarily as a respiratory disease, with symptoms that include cough, shortness of breath, and, in severe cases, acute respiratory distress syndrome and pneumonia

10 Dec 2020

SARS-CoV-2 spike protein mediates acute lung pathology in mice

A study shows that the viral spike protein is adequate by itself to induce macrophage activation in pulmonary tissue and induce acute inflammation.

10 Dec 2020

The effects of cigarette smoke and COPD on SARS-CoV-2 infection

Researchers have revealed some of the effects of cigarette smoke and chronic obstructive pulmonary disease (COPD) on SARS-CoV-2 infection.

9 Dec 2020

Why is COVID-19 more severe among adults than children?

Researchers in Switzerland and Australia have reviewed some of the mechanisms proposed regarding why coronavirus disease 2019 (COVID-19) is generally less severe among children than among adults.

8 Dec 2020

COVID-19 may be linked to acute appendicitis in children

Researchers at the University of Virginia have recently presented a case series pointing to a potential association between infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the development of acute appendicitis in children.

8 Dec 2020

Transmission dynamics of SARS-CoV-2 in children: an Indian case study

Researchers have studied the primary contacts of COVID-19 positive children in India in May 2020 and found all children to be asymptomatic, and only four of the parents became positive. Although this suggests lower transmission from children, no recommendations can be made yet on school reopening.

8 Dec 2020

Bioactive tea compounds show potential anti-SARS-CoV-2 activity

Scientists have revealed that certain bioactive compounds found in green, black, and oolong tea possess remarkable antiviral activities against SARS-CoV-2.

8 Dec 2020

Angiotensin Converting Enzyme 2 News and Research

Study may help explain how COVID-19 increases stroke risk

Higher COVID-19 mortality among certain groups in Colombia linked to structural inequalities

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

SARS-CoV-2 spike deletion ΔH69/ΔV70 shows repeated emergence and spread

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

Study shows an inflammatory response in the mice brain is responsible for severe COVID-19

Why are some groups more vulnerable to COVID-19?

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

Neanderthal gene variant increases risk of severe COVID-19

D614G mutation promotes lysosomal trafficking of SARS-CoV-2 spike protein

Distant residues modulate the conformational opening in SARS-CoV-2 spike protein

COVID-19 infection may also affect the central nervous system, cause neurological disorders

SARS-CoV-2 spike protein mediates acute lung pathology in mice

The effects of cigarette smoke and COPD on SARS-CoV-2 infection

Why is COVID-19 more severe among adults than children?

COVID-19 may be linked to acute appendicitis in children

Transmission dynamics of SARS-CoV-2 in children: an Indian case study

Bioactive tea compounds show potential anti-SARS-CoV-2 activity

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