Anti Inflammatory News and Research

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Etanercept found to be ineffective in treating alcoholic hepatitis

A new study from Mayo Clinic finds the use of the drug therapy etanercept ineffective in treating alcoholic hepatitis, an acute inflammation of the liver caused by excessive consumption of alcohol. The results of the study are published in the December issue of Gastroenterology.

1 Dec 2008

Research identifies cell receptor as target for anti-inflammatory immune response

Cell reception. By comparing normal mice (left) with mice that are genetically engineered to lack certain receptors in their spleen (right), scientists have shown SIGNR1 receptors (blue) are required to facilitate an anti-inflammatory action.

28 Nov 2008

Call for greater caution in prescribing inhaled corticosteroids to COPD sufferers

Lung disease experts at Johns Hopkins are calling for physicians to show much greater caution in prescribing inhaled corticosteroid drugs for people with chronic obstructive pulmonary disease after finding evidence that the widely used anti-inflammatory medications increase the risk of pneumonia by a full third.

25 Nov 2008

New model predicts risk of recurrence in early stage colon cancer patients

Researchers in the Duke Institute for Genome Sciences & Policy have developed a model for predicting risk of recurrence in early stage colon cancer patients, and have used the model to also predict sensitivity to chemotherapy and targeted therapy regimens.

24 Nov 2008

Long-term use of a macrolide antibiotic reduce COPD exacerbations, raise questions

Long-term use of a macrolide antibiotic may reduce the frequency of exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) by as much as 35 percent, according to a London-based study.

21 Nov 2008

Light drinking has certain health benefits, researchers look at why

While the physiological damage and social havoc created by alcohol abuse and dependency are well-known, it is also true that light-to-moderate drinking has certain health benefits.

20 Nov 2008

Metabolex announces positive results from phase 2 trial of MBX-8025

The Phase 2 study was a randomized, double-blind, placebo-controlled clinical trial evaluating the safety and efficacy of MBX-8025, both alone and in combination with atorvastatin (marketed as Lipitor(R)), over an 8-week treatment period.

19 Nov 2008

High levels of social support may protect brain during stroke

New research in mice suggests that high levels of social support may provide some protection against strokes by reducing the amount of damaging inflammation in the brain.

18 Nov 2008

Recent Southern California wildfires caused hospital visits for respiratory illnesses to spike

Raging wildfires that engulfed Southern California earlier this decade not only destroyed neighborhoods laying in their path, they also caused significant health problems for many who lived outside the fires' reach.

18 Nov 2008

Discovery of new mechanism that regulates formation of blood vessels

Researchers in one of the external groups of the Instituto Gulbenkian de Ciencia (IGC), in Portugal, have discovered a novel mechanism which regulates the process whereby new blood vessels are formed and wounds heal, including chronic wounds, such as those found in diabetic patients and those suffering from morbid obesity.

17 Nov 2008

Discovery of key contributor to Alzheimer's disease process

Walter J. Lukiw, PhD, Associate Professor of Neuroscience and Ophthalmology at LSU Health Sciences Center New Orleans, is the lead author of a paper identifying, for the first time, a specific function of a fragment of ribonucleic acid (RNA), once thought to be no more than a byproduct, in regulating inflammation and the development of Alzheimer's disease.

16 Nov 2008

Aspirin lowers PSA levels

The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is significantly associated with lower PSA levels, especially among men with prostate cancer, say researchers at Vanderbilt University.

16 Nov 2008

Phosphagenics' diclofenac enters trial phase in humans

Phosphagenics Limited ("Phosphagenics") announced today that it has initiated a phase 1 human clinical trial using its patented drug delivery system, TPM, for the targeted delivery of a leading non steroidal anti-inflammatory drug (NSAID), diclofenac.

12 Nov 2008

NicOx's Naproxcinod shows highly significant reduction in daytime blood pressure versus Naproxen

NicOx S.A. has announced that a new analysis of the data from the 104 Ambulatory Blood Pressure Monitoring (ABPM) study for naproxcinod was presented yesterday at the American Heart Association Scientific Sessions 2008, in New Orleans, USA.

12 Nov 2008

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

VIA Pharmaceuticals, Inc. has announced the results of two Phase 2 studies of its lead drug, VIA-2291.

10 Nov 2008

New research on chronic corticosteroid use

An analysis of large population databases has recently yielded important findings about chronic corticosteroid use.

10 Nov 2008

Barriers to managing asthma

Barriers to managing asthma include access to appropriate care, patient adherence, distrust of the medical profession, delayed asthma diagnosis, culture, lifestyle choices and genetic discrepancies according to experts at the annual meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Seattle.

10 Nov 2008

Fat tissue found to produce melanin

A two-year study conducted by researchers at George Mason University, INOVA Fairfax Hospital and the National Cancer Institute may open the door to new therapies for combating chronic diseases associated with obesity, a condition that affected more than 33 percent of American adults in 2005-06 according to the Centers for Disease Control and Prevention.

7 Nov 2008

Wide variability in rheumatoid arthritis drug Methotrexate suggests alternative dosing should be considered

Methotrexate (MTX) is commonly used to treat rheumatoid arthritis (RA) and is suggested as the "anchor" drug in treating the disease.

5 Nov 2008

Nicotinamide, a form of vitamin B3, reduces Alzheimer's symptoms

An over-the-counter vitamin in high doses prevented memory loss in mice with Alzheimer's disease, and UC Irvine scientists now are conducting a clinical trial to determine its effect in humans.

5 Nov 2008