Anti Inflammatory News and Research

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Arana files U.S. IND for lead anti-Inflammatory

Biotechnology company Arana Therapeutics Limited today announced it has submitted an Investigational New Drug application (IND) to the FDA (U.S. Food and Drug Administration) for the anti-inflammatory product ART621 in a rheumatoid arthritis (RA) indication.

29 Sep 2008

Isoflavone dietary supplement improves the functioning of the arteries in stroke patients

A dietary supplement containing isoflavone - a chemical found in soybeans, chickpeas, legumes and clovers - can improve artery function in stroke patients according to new research published online in Europe's leading cardiology journal, the European Heart Journal today.

23 Sep 2008

Anti-inflammatory drugs may mask prostate cancer marker

Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, may reduce serum levels of the prostate biomarker, PSA (prostate specific antigen), and hence may alter the detection of prostate cancer in individuals who take these medications.

14 Sep 2008

New drug promises once-a-day treatment for asthma and hay fever

The drug RPL554 apparently has the potential to effectively treat the respiratory diseases but without many of the side-effects most currently available drugs produce.

10 Sep 2008

Common painkillers lower levels of prostate cancer biomarker

Common painkillers like aspirin and ibuprofen appear to lower a man's PSA level, the blood biomarker widely used by physicians to help gauge whether a man is at risk of prostate cancer.

9 Sep 2008

Study identifies proteins that help provide immunity against HIV among commercial sex workers in Kenya

In a study published Wednesday in the Journal of Proteome Research, researchers from the University of Manitoba, along with participants from Canada's National Microbiology Laboratory and the University of Nairobi, indentified more than 15 proteins in a group of Kenyan commercial sex workers thought to have a natural immunity to HIV, the Winnipeg Free Press reports (Tremain, Winnipeg Free Press, 9/4).

9 Sep 2008

Common painkillers may lower a man's risk of prostate cancer

Scientists are suggesting that common painkillers such as aspirin and ibuprofen could possibly lower a man's risk of developing prostate cancer

8 Sep 2008

FDA assigns priority review to ATryn from GTC Biotherapeutics

The US Food and Drug Administration, or FDA, has assigned Priority Review to GTC Biotherapeutics, Inc.'s Biologic License Application, or BLA, for ATryn.

4 Sep 2008

Alte Biosciences files patent for novel inflammatory bowel disease drugs

Alte Bioscience, Inc., a development stage pharmaceutical company, is pleased to announce the filing of a provisional patent for a new class of drugs that may benefit patients with inflammatory bowel disease.

3 Sep 2008

Antiangiogenic and anti-inflammatory drugs: are they safe?

Since Rofecoxib (Vioxx) was withdrawn from the worldwide market based on the safety findings of the Adenomatous Polyp Prevention on Vioxx (APPROVe) study, the uncertainty around the cardiovascular safety of NSAIDs and COX-2 inhibitors remains and leaves practitioners with difficult management decisions for the hundreds of millions of patients worldwide who continue to require pain-relieving therapy to maintain an acceptable quality of life.

1 Sep 2008

Issues on cholesterol: diet, statins and genetics

Genetic lipoprotein disorders are frequently seen in patients with premature coronary artery disease (CAD). An example of strong genetic predisposition is the disorder: familial hypercholesterolemia, where a single gene defect (the low density lipoprotein receptor) contributes to most of the familial expression of CAD.

1 Sep 2008

Fluvastatin XL use is associated with improved cardiac outcome after major vascular surgery

The DECREASE III Study which took place in the Netherlands between June 2004 and April 2008, showed that patients treated with Fluvastatin showed an improved cardiac outcome after surgery.

1 Sep 2008

New genetic link to inflammatory bowel diseases discovered

A study which entailed scientists trawling through the genetic code of thousands of people, has revealed two new genes involved in childhood inflammatory bowel disease, a painful condition that includes Crohn's disease and ulcerative colitis (UC).

1 Sep 2008

Ortho-McNeil to appeal patent ruling on Razadyne

Ortho-McNeil Neurologics, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. announced that it will appeal yesterday's decision by the U.S. District Court of Delaware, which ruled the patent for Razadyne (galantamine hydrobromide) is invalid.

28 Aug 2008

New cutting edge laser technology provides view into body's chemical messenger system

Researchers at The University of Nottingham have developed a unique technology that will allow scientists to look at microscopic activity within the body's chemical messenger system for the very first time, live as it happens.

28 Aug 2008

Chronic stress alters our genetic immune response

Most people would agree that stress increases your risk for illness and this is particularly true for severe long-term stresses, such as caring for a family member with a chronic medical illness. However, we still have a relatively limited understanding of exactly how stress contributes to the risk for illness. In the August 15th issue of Biological Psychiatry, researchers shed new light on one link between stress and illness by describing a mechanism through which stress alters immune function.

27 Aug 2008

NicOx updates on PF-03187207 and research collaboration with Pfizer

NicOx S.A. has announced the results of a dose-ranging phase 2 study conducted with PF‑03187207 in Japanese patients with glaucoma by its partner Pfizer Inc. PF-03187207 is a nitric oxide-donating prostaglandin analog. The study was designed to compare the safety and efficacy of several doses of PF-03187207 to Xalatan (latanoprost) and enrolled 112 Japanese patients with primary open-angle glaucoma or ocular hypertension.

25 Aug 2008

Aspirin, acid-blocker a-day keeps GI bleeding at bay

For patients with clogged heart arteries who take long-term, low-dose aspirin to prevent a cardiac event, adding a stomach acid-blocking drug to their daily routine has been shown to reduce their risk for upper gastrointestinal bleeding - an infrequent, but serious side-effect of regular aspirin use.

11 Aug 2008

Frankincense reduces the symptoms of osteoarthritis

An enriched extract of the 'Indian Frankincense' herb Boswellia serrata has been proven to reduce the symptoms of osteoarthritis. Research published today in BioMed Central's open access journal Arthritis Research & Therapy has shown that patients taking the herbal remedy showed significant improvement in as little as seven days.

29 Jul 2008

Fish oil supplements could slow wound healing

A recent study shows that popular fish oil supplements have an effect on the healing process of small, acute wounds in human skin. But whether that effect is detrimental, as researchers initially suspected, remains a mystery.

23 Jul 2008