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Alarmin molecule identified as therapeutic target for allergic respiratory diseases

One of the molecules responsible for triggering the inflammation that causes allergic respiratory diseases, such as asthma and allergic rhinitis, has just been discovered by scientists from the CNRS, Inserm and the Université Toulouse III – Paul Sabatier.

12 Apr 2024

Study reveals unexpected vulnerability of lung immune cells to SARS-CoV-2

The lung-cell type that's most susceptible to infection by SARS-CoV-2, the virus that causes COVID-19, is not the one previously assumed to be most vulnerable.

10 Apr 2024

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).

10 Apr 2024

Maternal influences on food allergy prevention: A closer look at diet and environment

Review assesses how maternal diet and environmental factors during pregnancy influence the prevention of food allergies in offspring, underlining the importance of a balanced diet and questioning the efficacy of allergen avoidance.

9 Apr 2024

Researchers find new clues to understanding the progression of primary membranous nephropathy

No therapies currently exist that can halt the progression of chronic kidney disease in children or restore the ability of kidney cells to filter blood.

9 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Gold nanoparticle adorned polymers boost infectious disease testing

By harnessing the power of composite polymer particles adorned with gold nanoparticles, a group of researchers have delivered a more accurate means of testing for infectious diseases.

5 Apr 2024

Therapeutic potential of CD20 x CD3 bispecific antibodies

On Monday, March 25th, 2024, the U.S. FDA declined approval for Regeneron’s Odronextamab for two forms of lymphoma due to concerns over the progress of ongoing confirmatory trials.

From Sino Biological Inc. 5 Apr 2024

Muscles in microgravity: Spaceflight duration impacts muscle protein stress markers

Study explores the differential effects of short and long-duration space missions on muscle protein nitrosylation in astronauts, indicating adaptations and potential impairments in muscle function due to microgravity, and highlights the role of inflight exercise in mitigating some negative effects on muscle health.

3 Apr 2024

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain.

3 Apr 2024

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Researchers in Brazil have used an innovative technique in molecular biology to identify targets for candidate vaccines against Schistosoma mansoni, the parasite that causes schistosomiasis.

2 Apr 2024

Research suggests booster doses may be necessary for monkeypox immunity

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that even in men who receives two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.

1 Apr 2024

Study reveals waning antibody response to monkeypox vaccine over time

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that the antibodies produced by Modified Vaccinia virus Ankara - Bavarian Nordic (MVA-BN) vaccination against mpox wane significantly within a year of receiving the vaccination – but in people with pre-existing immunity due to childhood smallpox vaccination in childhood, antibody levels remain high in almost all cases.

1 Apr 2024

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Study demonstrated that selectively reducing myeloid-biased hematopoietic stem cells (my-HSCs) in aged mice rejuvenated the immune system, enhanced lymphopoiesis, reduced inflammation, and improved responses to viral infection, highlighting a potential strategy for countering age-related immune decline.

31 Mar 2024

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

31 Mar 2024

An ActRIIA fusion protein got FDA approved for PAH treatment

On March 26th, the US FDA granted approval for Merck’s WINREVAIR™ (sotatercept-csrk), marking a significant milestone in pulmonary arterial hypertension (PAH) treatment. PAH, characterized by elevated blood pressure in the arteries connecting the heart and lungs, poses a grave risk of heart failure.

From Sino Biological Inc. 28 Mar 2024

Antibodies News and Research

Alarmin molecule identified as therapeutic target for allergic respiratory diseases

Study reveals unexpected vulnerability of lung immune cells to SARS-CoV-2

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

Maternal influences on food allergy prevention: A closer look at diet and environment

Researchers find new clues to understanding the progression of primary membranous nephropathy

Research identifies how leukemia develops resistance to first line treatments

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Gold nanoparticle adorned polymers boost infectious disease testing

Therapeutic potential of CD20 x CD3 bispecific antibodies

Muscles in microgravity: Spaceflight duration impacts muscle protein stress markers

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Research suggests booster doses may be necessary for monkeypox immunity

Study reveals waning antibody response to monkeypox vaccine over time

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

DNA repair process key to memory formation, study finds

An ActRIIA fusion protein got FDA approved for PAH treatment

Scientists develop an mRNA technology approach to target Alzheimer’s disease

Antibody discovery could explain mysteries about COVID-19 and long COVID

Early understanding of diabetes risk could help in better disease management

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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