Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Personalized neuromodulation approach provides relief from severe depression symptoms

Targeted neuromodulation tailored to individual patients' distinctive symptoms is an increasingly common way of correcting misfiring brain circuits in people with epilepsy or Parkinson's disease.

18 Jan 2021

New combination treatment may provide relief for patients with methamphetamine use disorder

A new treatment that combines two existing medications may provide long-sought relief for many battling debilitating methamphetamine use disorder, according to a study to be published tomorrow in The New England Journal of Medicine.

15 Jan 2021

Metabolites may be predictive indicators of patients at risk for recurrent major depression

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -; small molecules produced by the process of metabolism -; may be predictive indicators for persons at risk for recurrent major depressive disorder.

12 Jan 2021

Epigenetic modulators have a rapid antidepressant-like effect, study shows

Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants.

4 Jan 2021

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.

17 Dec 2020

MIPT researchers use zebrafish to study chronic stress

A team of researchers led by MIPT's Allan Kalueff has studied chronic stress in zebrafish and determined that the animal can serve as a valuable model species for research into the associated brain diseases, complementing research currently done on rodents.

14 Dec 2020

Landmark heart study reveals new insights about risk factors for depression

Recently published UT Southwestern research reveals new insights about risk factors for depression based on data from a landmark longitudinal study focused on heart disease.

14 Dec 2020

Healthy gut microbiota contributes to normal brain function, study shows

Depression is a mental disorder that affects more than 264 million people of all ages worldwide. Understanding its mechanisms is vital for the development of effective therapeutic strategies.

11 Dec 2020

Researchers assess benefits of magnetic seizure therapy to treat depression in bipolar patients

Researchers are assessing whether magnetic seizure therapy (MST) can help relieve treatment-resistant depression in bipolar patients in a clinical trial led by The University of Texas Health Science Center at Houston (UTHealth).

24 Nov 2020

Antidepressant may prevent worsening of COVID-19 infection, study suggests

The antidepressant fluvoxamine appears to prevent COVID-19 infections from worsening and may help keep patients out of the hospital, a trial based on research from the University of Virginia School of Medicine suggests.

15 Nov 2020

Antidepressant drug fluvoxamine may prevent some serious complications of COVID-19

In a preliminary study of COVID-19 patients with mild-to-moderate disease who were attempting to recover in their homes, researchers at Washington University School of Medicine in St. Louis have found that the drug fluvoxamine seems to prevent some of the most serious complications of the illness and make hospitalization and the need for supplemental oxygen less likely.

12 Nov 2020

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

St Petersburg University researchers, led by Professor Raul R. Gainetdinov, Director of the Institute of Translational Biomedicine and Academic Supervisor of the St Petersburg University Hospital, have found a new role for recently discovered neurotransmitter system that uses the trace amine-associated receptor 5 (TAAR5) for neurotransmission.

11 Nov 2020

Delirium common after hospital discharge in critically ill COVID-19 patients

Anesthesiologist and other researchers from Michigan Medicine, Ann Arbor, New York Medical College, Valhalla and Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, have reported a case series of critically ill coronavirus disease 2019 (COVID-19) patients who have developed neuropsychological symptoms after having been discharged from the hospital.

8 Nov 2020

Psilocybin may be effective in patients suffering from major depression

In a small study of adults with major depression, Johns Hopkins Medicine researchers report that two doses of the psychedelic substance psilocybin, given with supportive psychotherapy, produced rapid and large reductions in depressive symptoms, with most participants showing improvement and half of study participants achieving remission through the four-week follow-up.

4 Nov 2020

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Some of the principal treatments for osteoporosis, denosumab, zoledronate and calcium, could have a protective effect against COVID-19 in patients who take them, specifically a 30 to 40% reduction in the rate of infection, according to the results of a joint study by Hospital del Mar, the Hospital del Mar Medical Research Institute (IMIM), Pompeu Fabra University and the Pere Virgili Health Park.

3 Nov 2020

Brain imaging biomarker may help predict treatment response in patients with psychiatric disorders, study reveals

Cohen Veterans Bioscience, a non-profit research biotech advancing brain health solutions, today announces findings from a study which generates new evidence in support of a critical brain imaging biomarker, that may help guide people who suffer from post-traumatic stress disorder or major depressive disorder towards the most effective treatment.

21 Oct 2020

Meditation and yoga can be a viable option for people seeking chronic pain relief

A mindfulness-based stress reduction (MBSR) course was found to benefit patients with chronic pain and depression, leading to significant improvement in participant perceptions of pain, mood and functional capacity, according to a study in the Journal of the American Osteopathic Association.

1 Oct 2020

Study reveals how subanesthetic ketamine is effective in treating adult amblyopia

In a new study, published in Current Biology, researchers from the University of California, Irvine School of Medicine reveal how subanesthetic ketamine, which is used for pain management and as an antidepressant in humans, is effective in treating adult amblyopia, a brain disorder commonly known as "lazy eye."

30 Sep 2020

First clinical trial launched to test psilocybin therapy for depression in cancer patients

The first clinical trial to test the safety and feasibility of psilocybin therapy with simultaneous administration and one-on-one patient support to treat depression in cancer patients was launched today by Maryland Oncology Hematology at the Aquilino Cancer Center at Adventist HealthCare Shady Grove Medical Center.

16 Sep 2020

Study: Significant proportion of older dental patients inappropriately prescribed opioids

A new study by researchers at the University of Illinois Chicago and the University of Pittsburgh suggests that a significant proportion of older patients receiving opioids at dental visits also use psychotropic medications -- a potentially harmful combination.