Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

University of Illinois at Chicago receives $2.2 million grant to develop drugs to suppress cocaine cravings

The University of Illinois at Chicago College of Pharmacy has received a $2.2 million federal grant to develop therapeutics to suppress the cravings of cocaine addicts.

19 Nov 2007

Bupropion plus counseling appears to help adolescents quit cigarette smoking in the short term

Almost one-fourth of U.S. high school students currently smoke cigarettes, according to background information in the article. Many teen smokers want to quit, but studies estimate that only about 4 percent of those who try are successful each year.

6 Nov 2007

Brain chemical anandamide work as antidepressant

American and Italian researchers have found that boosting the amounts of a marijuana-like brain transmitter called anandamide produces antidepressant effects in test rats.

6 Nov 2007

Trial of the antidepressant fluoxetine for teens with depression and substance use disorders

The antidepressant fluoxetine combined with cognitive behavioral therapy appears as effective for treating depression among teens who also have substance use disorders as among those without substance abuse problems, according to a report in the November issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

6 Nov 2007

Fabre Kramer Pharmaceuticals receives FDA decision on Gepirone ER for major depressive disorder

Fabre-Kramer Pharmaceuticals Inc. (FKP) and GlaxoSmithKline announced today that the U.S. Food and Drug Administration (FDA) has issued a not approvable letter for the new drug application for gepirone extended- release (ER) tablets, submitted for the treatment of adults with major depressive disorder.

5 Nov 2007

Key findings for all veterans seen in depression and suicide study

The largest and most up-to-date study of suicides among depressed veterans provides important new data that may help guide screening and treatment for all veterans.

31 Oct 2007

Veterans' suicide study yields key findings

The largest and most up-to-date study of suicides among depressed veterans provides important new data that may help guide screening and treatment for all veterans.

30 Oct 2007

Synthetic form of THC is an effective anti-depressant at low doses

A new neurobiological study has found that a synthetic form of THC, the active ingredient in cannabis, is an effective anti-depressant at low doses.

24 Oct 2007

Little evidence to support therapies for post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) is a severe and ongoing emotional reaction to an extreme psychological trauma; it affects significant numbers of people, in particular military personnel and veterans, who have seen active duty in war zones.

22 Oct 2007

Review of PTSD treatments

Many people, including significant proportions of active duty military personnel and veterans, suffer from post-traumatic stress disorder (PTSD), often in conjunction with other injuries or illnesses.

19 Oct 2007

Psychosocial and psychological interventions for treating postpartum depression

For the estimated 13 percent of new mothers who experience postpartum depression, counseling and peer support groups appear to offer symptom relief without medication, a new review of research suggests.

17 Oct 2007

Depression among patients with coronary artery disease

Depression has long had a popular link to cardiovascular disease and death. However, only during the last 15 years scientific evidence supporting this common wisdom has been available (Glassman et al., 2007a).

16 Oct 2007

How does the opioid system work?

The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).

15 Oct 2007

What's wrong with being shy?

What's wrong with being shy, and just when and how did bashfulness and other ordinary human behaviors in children and adults become psychiatric disorders treatable with powerful, potentially dangerous drugs?, asks a Northwestern University scholar in a new book that already is creating waves in the mental health community

12 Oct 2007

Taking antidepressants with painkillers dangerous

Taking antidepressants together with painkillers can substantially increase the risk of bleeding from the stomach, according to new research by the University of East Anglia.

9 Oct 2007

SSRIs may double risk of gastrointestinal bleeding

New research shows that selective serotonin reuptake inhibitors (SSRIs), a group of drugs commonly used to treat depression, may double the risk of gastrointestinal bleeding, according to researchers from Wake Forest University School of Medicine and colleagues.

9 Oct 2007

New test detects the presence of biogenic amines

Researchers in California are reporting development of a fast, inexpensive test suitable for home use that could help millions of people avoid those 'out of the blue' headaches that may follow consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.

2 Oct 2007

Depressed adolescents respond best to psychotherapy and antidepressant medication

A combination of psychotherapy and antidepressant medication appears to be the most effective treatment for adolescents with major depressive disorder - more than medication alone or psychotherapy alone, according to results from a major clinical trial funded by the National Institutes of Health's National Institute of Mental Health (NIMH).

2 Oct 2007

Variations in two genes linked to suicidal thinking

Specific variations in two genes are linked to suicidal thinking that sometimes occurs in people taking the most commonly prescribed class of antidepressants, according to a large study led by scientists at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

27 Sep 2007

Genetic test announced for suicidal ideation in patients using antidepressant drugs

NeuroMark, a Boulder, Colorado company, announced today the immediate availability of a genetic test to identify people at risk of suicidal ideation - thoughts of committing suicide - when prescribed an antidepressant drug.

27 Sep 2007