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Research shows how food poisoning bacteria can multiply and spread inside micro-organisms

New research by a team from London's Kingston University has shown how the food poisoning bacteria Campylobacter can multiply and spread inside micro-organisms called amoebae- which could lead to a better understanding of how bacteria survive and help efforts to prevent the spread of infection.

14 Nov 2017

Research casts light on how chromosomes 'cheat' for chance to get into a sex cell

Each of your cells contains two copies of 23 chromosomes, one inherited from your father and one from your mother. Theoretically, when you create a gamete -- a sperm or an egg -- each copy has a 50-50 shot at being passed on. But the reality isn't so clearcut.

3 Nov 2017

SU2C and its collaborators announce four teams to intercept cancer at earliest stages

Stand Up To Cancer, joined by the Lustgarten Foundation for Pancreatic Cancer Research, LUNGevity, and the American Lung Association, announced today four teams of top researchers who will carry out an attack on cancers of the lung and pancreas using a radical new approach of “interception” of cancers at very early stages, when they can be more successfully treated.

31 Oct 2017

Study reveals why Alzheimer's drugs fail in clinical trials

A tremendous amount of Amyloid-β peptide (Aβ) (a peptide of ～40 amino acids) accumulates in the brain of Alzheimer's disease patients. γ-Secretase inhibitors were designed to inhibit the enzymatic activity that produces Aβ. By reducing Aβ production, γ-secretase inhibitors were considered able to treat Alzheimer's disease (Aβ hypothesis).

25 Oct 2017

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells.

24 Oct 2017

Queen's University Belfast leads new research to better understand biology of prostate cancer

Queen's University Belfast has led the world's largest research study using a diagnostic test developed by Almac Diagnostics, to better understand the biology of prostate cancer tumors, which could lead to a transformation in how prostate cancer is diagnosed and treated.

23 Oct 2017

Novel gene expression signature assay could help enhance lymphoma management

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer and the most frequently diagnosed non-Hodgkin lymphoma worldwide (nearly 40% of cases). Recent advancements indicate that both the prognosis and choice of treatment of DLBCL may depend on identifying its molecular subtype.

17 Oct 2017

Scientists develop revolutionary blood screening test to diagnose breast cancer

In a potential major breakthrough in breast cancer research, scientists at the Center for Translational Cancer Research at the Helen F. Graham Cancer Center & Research Institute of Christiana Care Health System have developed a revolutionary new blood test to diagnose breast cancer.

16 Oct 2017

IGeneX launches three new tests to aid diagnosis of Borreliosis

IGeneX Inc., a CLIA and New York-approved Reference Laboratory, specializing in testing for tick-borne diseases, is pleased to announce the launch of three new tests that are more inclusive and specific for aiding in diagnosis of Borreliosis (Lyme Disease and Tick-Borne Relapsing Fever, Borreliosis).

16 Oct 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

EKF Diagnostics and Ortho Clinical Diagnostics collaborate on a new diabetic ketoacidosis assay

Ortho Clinical Diagnostics and EKF announce an agreement that allows Ortho customers to access to Beta-Hydroxybutyrate assay.

From EKF Diagnostics 12 Oct 2017

UCLA scientists discover potential combination treatment for brain cancer in adults

UCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by Dr. David Nathanson, a member of UCLA's Jonsson Comprehensive Cancer Center, found that the drug combination tested in mice disrupts and exploits glucose intake, essentially cutting off the tumor's nutrients and energy supply.

9 Oct 2017

Increased fFN testing could help provide better care for women with symptoms of preterm labor

A new study found that women with symptoms of preterm labor who were discharged from the hospital without a fetal fibronectin (fFN) test were more likely to deliver their baby prematurely within three days compared to women who were discharged with an fFN test, Hologic, Inc. announced today.

6 Oct 2017

Liquid biopsy can reveal response to checkpoint inhibitor-based immunotherapies

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies.

3 Oct 2017

Alterations in circulating tumor DNA associated with response to checkpoint inhibitors

The number of alterations detected in the DNA collected from blood samples (liquid biopsies) of cancer patients treated with immune checkpoint inhibitors was associated with response to the treatment.

3 Oct 2017

DuraClone RE antibody panels improve detection of rare, abnormal events in blood disorders

Beckman Coulter Life Sciences has taken the detection of rare, abnormal events in blood disorders forward, with intro of antibody panels.

From Beckman Coulter Life Sciences - Flow Cytometry 28 Sep 2017

Chromatrap ChIP-Seq kits can deliver streamlined protocol from nanograms of starting material

Chromatrap has demonstrated that its unique solid state patented technology allows for ChIP-seq assays to be routinely performed from as little as 500 ng of chromatin.

From Chromatrap® - Porvair Sciences Ltd 28 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Study presents new method for tracing history of β-cells

Tracing the history of individual cells in the developing organism can reveal functional differences among seemingly uniform cells. This knowledge is important for defining the characteristics of highly regenerative cells in order to target them for cellular therapies, as well as to prevent the formation of unfit cells, which compromise the overall health of the organism.

22 Sep 2017

Novel assay shows potential to detect circulating cancer biomarkers in blood samples

Future Science Group today announced the publication of an article in Future Science OA presenting early data from a novel assay for the non-invasive detection of PD-L1 and other biomarkers in patient blood samples.