Autoimmunity News and Research

RSS

Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Study uncovers new factor in the development of childhood lymphoma

A study recently published in the renowned journal Blood, led by Kaan Boztug, Scientific Director of the St. Anna Children's Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Associate Professor at the Medical University of Vienna, together with scientists from Israel, Germany, Turkey, Colombia, Argentina and the USA, investigated four patients from independent families with malignancy, autoimmunity and immunodeficiency.

19 Sep 2019

Gut bacterial changes influence lupus treatment results in pregnancy

The course of pregnancy, like that of true love, doesn’t always run smooth when you have lupus, correctly called systemic lupus erythematosus (SLE). This autoimmune disease is an occasionally violent, occasionally subdued, chronic inflammation that constantly smolders within multiple tissues in the body.

16 Sep 2019

Uncovering new T cell regulatory processes could help treat autoimmune disease

One of the important cells involved in the immune response is the T follicular helper (Tfh) cell. These are important in the normal process of antibody production following immunization, for instance. However, they are also abnormally increased in number in patients with autoimmune disease, such as systemic lupus erythematosus.

16 Sep 2019

Discovery may help identify signs of type 1 diabetes earlier

A new study showed that there are significant differences in the MHC class II antigens on the insulin peptide that is deficient in type 1 diabetes mellitus (T1DM). These determine the response of the T cells to the insulin peptide that causes destruction of insulin.

2 Sep 2019

Genetic risk for autoimmunity may be linked to differences in gut microbiome

Children with increased genetic risk of type 1 diabetes have different gut microbiomes than those with low risk, a new study found.

20 Aug 2019

New circulating immune cell could help predict type 1 diabetes risk

A new Finnish study suggests that type 1 diabetes may in part be caused by a novel subset of immune cells. This is because these cells, called peripheral T helper cells, are found to circulate at a higher rate in children with type 1 diabetes of recent onset, as well as in healthy children who later develop the condition.

20 Aug 2019

Lipid signaling pathway may enhance T cell-mediated immunotherapy

The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading detection by the immune system.

19 Aug 2019

High gluten intake during childhood increases risk of celiac disease

Children are more likely to develop celiac disease if they consume higher-than-average amounts of gluten during the first five years of life.

15 Aug 2019

Strategic partnership will help improve health outcomes for patients with autoimmune disease

The American Autoimmune Related Diseases Association announced today a strategic alliance with iMD Health Global that will help evolve communications between physicians and patients to improve health outcomes, focused on autoimmune and related diseases, which is estimated to affect over 50 million Americans.

18 Jul 2019

Researchers explain how 'viral' agents of neurological diseases ended up in our DNA

What if the missing ‘environmental’ factor in some of our deadliest neurological diseases were really written in our genome?

11 Jul 2019

Scientists identify mechanism that makes babies more likely than adults to die from sepsis

An immune mechanism that makes babies more likely than adults to die from sepsis has been identified by scientists affiliated with the Center for Research on Inflammatory Diseases in Ribeirão Preto, São Paulo State (Brazil).

4 Jul 2019

Antibodies could cause arthritic pain

Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report.

13 Jun 2019

CGM evaluations in long-term islet transplant recipients show near-normal glycemic profiles

Continuous glucose monitoring evaluations in islet transplant recipients who have been insulin independent for an average of 10 years show near-normal glycemic profiles and time-in-range metrics, according to data presented by the Diabetes Research Institute at the University of Miami Miller School of Medicine.

10 Jun 2019

High salt intake inhibits tumor growth in mice, shows study

A study by an international research team led by Professor Markus Kleinewietfeld shows that high salt intake inhibits tumor growth in mice.

6 Jun 2019

Researchers find new molecular targets for fighting autoimmunity

BRCA--the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers--interacts with a multipart, molecular complex that is also responsible for regulating the immune system.

30 May 2019

Newly identified internal regulator helps control body's response to fight infection

Scientists have identified a new internal regulator which helps control the body's response to fight infection.

30 May 2019

Research could lead to new treatments for people with autoimmune disorders

The immune system is programmed to rid the body of biological bad guys--like viruses and dangerous bacteria--but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the system mistakes normal cells for malicious invaders, prompting the body to engage in self-destructive behavior.

29 May 2019

New study shows how a kidney biopsy can be used to tailor treatment for lupus patients

The kidneys of patients living with systemic lupus erythematosus are often under assault, and not all those living with the disease will respond to standard treatment.

21 May 2019

Innovative transplantation technique helps find early signs of type 1 diabetes

By the time type 1 diabetes is diagnosed, most of the insulin-producing beta cells have already been destroyed.

15 May 2019

Increasing early beta-cell proliferation could halt development of type 1 diabetes

Many in-development cures for type 1 diabetes have understandably focused on tackling the autoimmune aspect of the disease before figuring out a way to replace the destroyed beta cells. But what if focusing on the beta cells first could prevent their destruction altogether?

7 May 2019