Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Calcium controls use of glucose by T cells to multiply and battle against infection, study finds

A calcium signal controls whether immune cells can use the nutrients needed to fuel their multiplication into a cellular army designed to fight invading viruses.

11 Oct 2017

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Cancer immunotherapy drugs only work for a minority of patients, but a generic drug now used to increase blood flow may be able to improve those odds, a study by Columbia University Medical Center researchers suggests.

7 Sep 2017

Feinstein researcher awarded NIH grant to better understand genetic causes of Alzheimer's disease

Feinstein Institute for Medical Research Assistant Professor Yun Freudenberg-Hua, MD, has been awarded a five-year, $600,000 grant from the National Institutes of Health's National Institute on Aging to identify genetic risk factors for Alzheimer's disease.

11 Aug 2017

Researchers find neuroprotective effects of trigeminal nerve stimulation in severe TBI

Researchers at the Feinstein Institute for Medical Research and the department of neurosurgery at the Hofstra Northwell School of Medicine, announced today that they have published a paper with research findings that could have implications for the treatment of many neurological conditions, including severe traumatic brain injury (TBI).

28 Jul 2017

Feinstein Institute professor finds protein as potential cause for lupus

Leading rheumatologist and Feinstein Institute for Medical Research Professor Betty Diamond, MD, may have identified a protein as a cause for the adverse reaction of the immune system in patients suffering from lupus.

14 Jul 2017

Intestinal viruses may affect person's chance of developing Type 1 diabetes

Doctors can't predict who will develop Type 1 diabetes, a chronic autoimmune disease in which one's own immune system destroys the cells needed to control blood-sugar levels, requiring daily insulin injections and continual monitoring.

11 Jul 2017

Stem Cell Educator therapy found to be safe and effective for treating diabetes

New research reveals that a treatment called Stem Cell Educator therapy is safe and effective for treating type 1 and type 2 diabetes. The therapy cultures the patient's immune cells with cord blood stem cells and returns only the "educated" immune cells to the patient's circulation.

7 Jul 2017

Researchers find new evidence that autoimmunity plays role in Parkinson's disease

Researchers have found the first direct evidence that autoimmunity- in which the immune system attacks the body's own tissues- plays a role in Parkinson's disease, the neurodegenerative movement disorder.

21 Jun 2017

Clinical study shows new mechanism that BCG vaccine uses to reverse advanced type 1 diabetes

Interim results from a FDA-approved clinical trial testing the generic vaccine bacillus Calmette-Guérin (BCG) to reverse advanced type 1 diabetes are being presented at the 75th Scientific Sessions of the American Diabetes Association.

12 Jun 2017

Joslin Diabetes Center researchers establish CCTD to develop and translate cell-based interventions

Researchers and clinicians at Joslin Diabetes Center have established a Center for Cell-Based Therapy for Diabetes, the goal of which is to lead the development and translation of cell-based interventions to treat and cure diabetes and its complications.

9 Jun 2017

Researchers find new way to block type 1 diabetes

Researchers at The Jackson Laboratory, Cyteir Therapeutics and collaborating institutions have found a way to protect beta cells from destruction -- achieving a longtime, elusive goal that could lead to therapies preventing type 1 diabetes (T1D).

1 Jun 2017

Feinstein Institute honors Sir Paul Nurse with Cerami Award for cancer research

Northwell Health's Feinstein Institute for Medical Research and Molecular Medicine announced today that the seventh Anthony Cerami Award in Translational Medicine will be awarded to Sir Paul Nurse, PhD, director of The Francis Crick Institute.

24 May 2017

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

Researchers discover cellular mechanism that underlies development of autoimmune diseases

A research team from iMM Lisboa led by Luís Graça has found a cellular mechanism that underlies the development of autoimmune diseases.

27 Apr 2017

UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types

Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types.

24 Apr 2017

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

With the help of genetically engineered mice, scientists at the Massachusetts General Hospital are moving closer to establishing the role that increased intestinal permeability, sometimes called a "leaky gut," plays in chronic inflammatory conditions.

20 Apr 2017

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Marc Symons, PhD, professor in The Feinstein Institute for Medical Research's Karches Center for Oncology Research, is examining if a common medication administered to treat pinworms, could replace the current treatment used for certain brain cancers.

11 Apr 2017

Feinstein Institute professor develops new tool to evaluate quality of eHealth applications

Feinstein Institute for Medical Research Assistant Professor Amit Baumel, PhD, has developed Enlight, a tool to evaluate the quality and therapeutic potential of computer and mobile-based eHealth applications.

31 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

A Japanese research group has discovered that a newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland).

2 Mar 2017