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Scientists uncover how hormones achieve their effects

The first quantitative study of protein complexes that transmit pheromone signals in living yeast cells sheds light on a crucial signalling process also found in humans.

22 Oct 2007

Gold-like drugs to treat arthritis

Scientists at Duke University Medical Center may have solved the mystery surrounding the healing properties of gold - a discovery they say may renew interest in gold salts as a treatment for rheumatoid arthritis and other inflammatory diseases.

22 Oct 2007

Heparanase shows potential as cancer drug

Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.

22 Oct 2007

Novel therapeutic device captures and treats cells as they flow through the blood stream

MIT and University of Rochester researchers report important advances toward a therapeutic device that has the potential to capture cells as they flow through the blood stream and treat them.

22 Oct 2007

Immune cells can simultaneously stimulate and inhibit killer cell activity

Dendritic cells, which are responsible for teaching other immune cells to attack infected or mutated cells, face a dangerous predicament.

22 Oct 2007

Critical need for earlier diagnosis and referral of HIV-infected children in Africa

Care provided by nurses and other clinicians in primary health care settings in sub-Saharan Africa can result in good outcomes for children with HIV infection.

22 Oct 2007

Good outcomes possible for HIV-infected children in Africa enrolled in pediatric treatment programs

Care provided by nurses and other clinicians in primary health care settings in sub-Saharan Africa can result in good outcomes for children with HIV infection.

22 Oct 2007

FDA approves approved Ixempra (ixabepilone) for advanced breast cancer

The U.S. Food and Drug Administration has approved Ixempra (ixabepilone), a new anti-cancer treatment, for use in patients with metastatic or locally advanced breast cancer who have not responded to certain other cancer drugs.

22 Oct 2007

New role discovered for cilia

Johns Hopkins researchers and colleagues have found a previously unrecognized role for tiny hair-like cell structures known as cilia: They help form our sense of touch.

22 Oct 2007

Extract of broccoli sprouts protects from ultraviolet radiation

A team of Johns Hopkins scientists reports in this week's issue of the Proceedings of the National Academy of Sciences that humans can be protected against the damaging effects of ultraviolet (UV) radiation - the most abundant cancer-causing agent in our environment - by topical application of an extract of broccoli sprouts.

22 Oct 2007

Breakthrough reveals important human receptor structure that will aid drug development

Scientists at the MRC Laboratory of Molecular Biology (LMB) in Cambridge have obtained the first clear images of the proteins that relay vital messages to cells.

22 Oct 2007

The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases

A phenomenon considered healthy for cells, such as the accumulation of long chains of glucose (glycogen), which tissues store for energy purposes, is harmful for neurons.

22 Oct 2007

Illumina launches MicroRNA assay for gene expression profiling

Illumina, Inc. today launched a MicroRNA Assay for Gene Expression profiling. Priced at $95 per sample, this assay is the only solution available to allow rapid and reproducible miRNA expression profiling at a price less than half that of other commercially available methods.

From Illumina, Inc. 22 Oct 2007

Stem cells to treat damaged eyes and a rare skin disorder

Doctors and scientists in Italy have shown how stem cells can be used to treat damaged eyes and, in combination with gene therapy, a rare and debilitating skin disease.

22 Oct 2007

Experts warn women about experimental fertility options

The American Society for Reproductive Medicine (ASRM) has warned women that two experimental fertility procedures currently being offered remain unproven.

22 Oct 2007

Brain mechanism may help some cope better in stressful situations

According to researchers in the U.S. a mechanism found in some people's brain could be the key to them staying relaxed in stressful situations.

22 Oct 2007

Ubiquitin builds up an immune response

Ubiquitin is a small protein, which can be attached to other cellular proteins, a process known as ubiquitination.

22 Oct 2007

GenVec receives extra funding for adenovector-based HIV vaccines program

GenVec, Inc. has announced that the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has executed its sixth option period (year seven) under its multi-year collaboration with GenVec to develop and manufacture novel adenovector-based HIV vaccines.

22 Oct 2007

Bacteria use plant defence for genetic modification

Bacteria that cause tumours in plants modify plant genomes by skilfully exploiting the plants' first line of defence.

22 Oct 2007

Smurfs a major cause of osteoarthritis

A new clinical trial seeks to predict who is most likely to experience osteoarthritis, and to test whether an experimental treatment can prevent it altogether.

19 Oct 2007