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AmpliPhi receives positive feedback from FDA for its AB-PA01 product targeting P.aeruginosa infections

AmpliPhi Biosciences Corporation, a clinical-stage biotechnology company focused on precisely targeted bacteriophage therapeutics for antibiotic-resistant infections, today announced that the company has received positive feedback, via written response, from the U.S. Food and Drug Administration regarding its development plans for AB-PA01, without the need for a Type B Pre-IND meeting.

19 Sep 2018

Weak antibiotic concentrations sufficient to increase antimicrobial resistance in laboratory conditions

Microbial communities are equipped with effective defense mechanisms against antibiotics. Existing antimicrobial resistance may become increasingly prevalent on its own - with no interference from antibiotics - in compact bacterial communities known as biofilms, or when protozoa hunt bacteria for food.

5 Sep 2018

Wound healing work presented at the RCP Innovation in Medicine Conference 2018 by Neem Biotech

Neem Biotech recently attended the Royal College of Physicians’ Innovation in Medicine Conference 2018 where Neem presented their data around wound-relevant biofilms.

From Neem Biotech 23 Aug 2018

Innovation in Wound Care

There are many definitions of hard-to-heal. More conventionally, it's based on underlying etiology of the wound, but in practice it's any wound that has not healed within a timely fashion. This is often due to a lack of coordinated care.

From Neem Biotech 22 Aug 2018

ASU joins with Mayo Clinic to move blue clays closer to medical use

Researchers at Arizona State University and the Mayo Clinic in Rochester, Minnesota, have found that at least one type of blue clay may help fight disease-causing bacteria in wounds, including antibiotic-resistant bacteria. The findings appear in the International Journal of Antimicrobial Agents.

21 Aug 2018

Clay may help fight disease-causing bacteria in wounds

The use of mud or wet clay as a topical skin treatment or a poultice is a common practice in some cultures and the concept of using mud as medicine goes back to earliest times.

21 Aug 2018

Catalytic nanoparticles can effectively prevent tooth decay

Combine a diet high in sugar with poor oral hygiene habits and dental cavities, or caries, will likely result.

1 Aug 2018

Softening agents added to drinking water may amplify risk of pathogen release

Many city drinking water systems add softening agents to keep plumbing free of pipe-clogging mineral buildup. According to new research, these additives may amplify the risk of pathogen release into drinking water by weakening the grip that bacteria - like those responsible for Legionnaires' disease - have on pipe interiors.

26 Jul 2018

Novel delivery system for bacteriophages could offer new way to battle lung infections

A new delivery system for bacteriophages-;viruses that selectively attack harmful bacteria-;could help give doctors a new way to battle lung infections that threaten older patients and people with cystic fibrosis.

17 Jul 2018

Component of cinnamon oil can help treat certain bacterial infections

Researchers have found that a major component of cinnamon oil can help to clear certain bacterial infections.

12 Jul 2018

Researchers develop biofilm formulations that protect from necrotizing enterocolitis

Most of the time, we think biofilms are bad news. And when pathogenic microbes form biofilms, they are.

11 Jul 2018

Bacteria use 'divide and conquer' strategy to defeat their enemies

Some bacteria can release toxins that provoke their neighbors into attacking each other, a tactic that could be exploited to fight infections.

3 Jul 2018

Timing may be key to evading destruction for bacteria facing antibiotics

For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth had a much better chance of surviving treatment.

30 Jun 2018

Award granted to Neem Biotech to develop antimicrobial intervention for chronic lung infections

Neem are working on a novel approach to antimicrobial resistance, which involves preventing the formation of and disrupts mature biofilms that are produced by bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus.

From Neem Biotech 18 Jun 2018

Coating medical devices with essential oils to prevent bacterial infections

James Cook University scientists have discovered a technique to apply natural plant extracts such as Tea Tree Oil as a coating for medical devices, a process which could prevent millions of infections every year.

7 Jun 2018

Neem Biotech present biofilm disruptor at BIO Boston 2018, to minimise antimicrobial resistance

Neem Biotech, a Wales based pharmaceutical biotech working in the field of novel antimicrobial research and development will present details of the company’s approach to minimising antimicrobial resistance through biofilm disruption at BIO Boston 2018.

From Neem Biotech 7 Jun 2018

Bacterium causing nosocomial infections uses tiny finger-like structures to infect medical tools

The antibiotic-resistant Acinetobacter baumannii bacterium is one of the most globally harmful bacteria that causes nosocomial infections.

1 Jun 2018

Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Overuse of antibiotics has led to the spread of multi-resistant bacteria that do not respond to conventional treatments.

29 May 2018

Researchers develop film to prevent bacteria from growing on dental retainers and aligners

Clear, plastic aligners have been growing in popularity as alternatives to bulky, metal braces. And once the teeth are straightened, patients graduate to plastic retainers to maintain the perfect smile.

24 May 2018

Antibacterial substance found in toothpaste may fight against life-threatening lung disease

Michigan State University researchers have found that when triclosan, a substance that reduces or prevents bacteria from growing, is combined with an antibiotic called tobramycin, it kills the cells that protect the CF bacteria, known as Pseudomonas aeruginosa, by up to 99.9 percent.

17 May 2018