Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New biomarker can predict breast cancer recurrence

Researchers from Virginia Commonwealth University Massey Cancer Center have discovered a new biomarker related to the body's immune system that can predict a breast cancer patients' risk of cancer recurrence.

17 May 2011

PGT, Quintiles collaborate to bring genomic testing into mainstream drug development

Quintiles, the world's leading biopharmaceutical services company, and Population Genetics Technologies Ltd., creator of innovative solutions to reduce the costs and complexity of large-scale genomic testing and enable correlations with clinical outcomes, today announced a commercial collaboration to bring genomic testing into mainstream drug development in order to produce safer, more effective medicines.

17 May 2011

Simple, minimal invasive technique could help detect early-stage lung cancer

A simple, minimally-invasive technique using cells from the interior of the nose could help clinicians detect lung cancer in its earliest - and most treatable - stages, according to a study conducted by researchers in Boston.

16 May 2011

Researchers uncover unexpected role of estrogen receptors in brain inflammation

Researchers have uncovered an unexpected role for estrogen receptors in the brain in keeping inflammation under control. The findings reported in the May 13 issue of the Cell Press journal Cell may have important implications for the treatment of multiple sclerosis (MS) and many other neurodegenerative diseases.

13 May 2011

Biocept's paper describes identification of different CTC phenotypes in cancer patients

Biocept, Inc., a privately-held laboratory testing company focused on the detection, enumeration and analysis of circulating tumor cells (CTCs) in cancer patients, today announced the publication of a paper describing the identification of different CTC phenotypes using its proprietary Cell Enrichment and Extraction platform.

12 May 2011

Cell Biosciences announces acquisition of Brightwell Technologies

Cell Biosciences, Inc. today announced that it has acquired Brightwell Technologies, Inc. of Ottawa, Ontario for approximately U.S. $9 million in cash.

12 May 2011

Reprogrammed herpes virus can improve early cancer diagnosis

Scientists have used a genetically re-engineered herpes virus that selectively hunts down and infects cancerous tumors and then delivers genetic material that prompts cancers to secrete a biomarker and reveal their presence.

12 May 2011

AspirinWorks Test now available in greater Boston and surrounding area

A simple urine test that measures aspirin effect is now available in the greater Boston and surrounding area. The AspirinWorks Test is available to eastern Massachusetts and southern New Hampshire area doctors through Diagnostic Laboratory Medicine.

11 May 2011

U.S. biopharmaceutical companies to benefit from Almac's European Product Launch workshop

Almac is hosting its inaugural European Product Launch workshop in Boston, MA on 17th May 2011. Targeted specifically at the biopharmaceutical sector, the workshop provides consultative advice and services to US companies to successfully launch drug products onto the European market.

11 May 2011

Long non-coding RNA promotes melanoma cell survival and invasion

Traditionally, RNA was mostly known as the messenger molecule that carries protein-making instructions from a cell's nucleus to the cytoplasm. But scientists now estimate that approximately 97 percent of human RNA doesn't actually code for proteins at all. A flurry of research in the past decade has revealed that some types of non-coding RNAs switch genes on and off and influence protein function.

11 May 2011

Rapid blood-based test can determine patients with SLE

"At present, it can take up to a year before a patient is diagnosed with SLE. This is because the symptoms are diffuse and are often mistaken for other diseases. However, with this blood-based test, it is possible to determine quickly whether someone has the disease or not", says Christer Wingren, associate professor in Immunotechnology at CREATE Health, Lund University.

10 May 2011

Treatment with estrogen-lowering drugs shrinks tumors and reduces mastectomy rates in breast cancer patients

In the first large trial of its kind in the United States, researchers have shown that estrogen-lowering drugs can shrink tumors and reduce mastectomy rates for patients with stage 2 or 3 breast cancer.

10 May 2011

Aethlon seeks FDA meeting for re-initiation of Hemopurifier IDE study

Aethlon Medical, Inc. announces that it has submitted a request to the U.S. Food and Drug Administration for a face-to-face meeting to discuss re-initiation of an Investigational Device Exemption (IDE) study of the Aethlon Hemopurifier in the United States.

10 May 2011

Acceleron presents RAP-661 preclinical data in osteopenic mice at international meeting

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, presented preclinical data highlighting the significant anabolic bone effects in normal and osteopenic mice of RAP-661.

10 May 2011

Epigenomics presents Septin9 blood test study data in colorectal cancer at DDW 2011

Epigenomics AG, the cancer molecular diagnostics company, reports that Dr. Uri Ladabaum, Associate Professor in the Department of Gastroenterology and Hepatology at the School of Medicine of Stanford University, has presented the results of a health economic analysis of potential future colorectal cancer screening with Septin9 blood tests at the ongoing Digestive Disease Week 2011.

9 May 2011

Epigenomics, Life Technologies enter supply agreement for second-generation colorectal cancer blood test

Epigenomics AG, the cancer molecular diagnosis company, today announced the signing of a supply agreement with Life Technologies Corporation, a global provider of innovative life science solutions.

7 May 2011

DiagnoCure to showcase Previstage GCC Colorectal Cancer Staging Test at ASCRS meeting

DiagnoCure, Inc., a life sciences company commercializing high‐value cancer diagnostic tests and delivering laboratory services, today reported that its PrevistageTM GCC Colorectal Cancer Staging Test will be featured at the annual meeting of the American Society of Colon and Rectal Surgeons to be held in Vancouver, Canada, from May 15 to 17, 2011, with 3,000 expected attendees.

6 May 2011

Promedior's PRM-151 clinical data in idiopathic pulmonary fibrosis to be presented at ATS 2011

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, today announced that data from a clinical study of PRM-151 will be presented at the 2011 American Thoracic Society International Conference, being held May 13-18, 2011 in Denver, CO.

5 May 2011

Researchers identify unexpected triple-negative breast cancer marker

German researchers have identified an unexpected molecular marker that predicts how sensitive hard-to-treat triple-negative breast cancers are to chemotherapy.

5 May 2011

Almac launches six enzyme screening kits

As anticipated, Almac's biocatalysis business has expanded from its 2009 launch with the sale of six enzyme screening kits, to the current supply of 100s of kgs of chiral intermediates for drug substance manufacture, regular enzyme supply to specialty chemical companies and continued growth of its screening kits offering. Biocatalysis is increasingly recognised as an alternative solution for solving complex chemistry problems due to its rapid implementation, economic benefits and 'green' reputation.

4 May 2011

Biomarker News and Research

Further Reading

New biomarker can predict breast cancer recurrence

PGT, Quintiles collaborate to bring genomic testing into mainstream drug development

Simple, minimal invasive technique could help detect early-stage lung cancer

Researchers uncover unexpected role of estrogen receptors in brain inflammation

Biocept's paper describes identification of different CTC phenotypes in cancer patients

Cell Biosciences announces acquisition of Brightwell Technologies

Reprogrammed herpes virus can improve early cancer diagnosis

AspirinWorks Test now available in greater Boston and surrounding area

U.S. biopharmaceutical companies to benefit from Almac's European Product Launch workshop

Long non-coding RNA promotes melanoma cell survival and invasion

Rapid blood-based test can determine patients with SLE

Treatment with estrogen-lowering drugs shrinks tumors and reduces mastectomy rates in breast cancer patients

Aethlon seeks FDA meeting for re-initiation of Hemopurifier IDE study

Acceleron presents RAP-661 preclinical data in osteopenic mice at international meeting

Epigenomics presents Septin9 blood test study data in colorectal cancer at DDW 2011

Epigenomics, Life Technologies enter supply agreement for second-generation colorectal cancer blood test

DiagnoCure to showcase Previstage GCC Colorectal Cancer Staging Test at ASCRS meeting

Promedior's PRM-151 clinical data in idiopathic pulmonary fibrosis to be presented at ATS 2011

Researchers identify unexpected triple-negative breast cancer marker

Almac launches six enzyme screening kits

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