Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Genetic proof for anti-cancer properties of antioxidants and autophagy inhibitors

Researchers from Jefferson's Kimmel Cancer Center have genetic evidence suggesting the antioxidant drugs currently used to treat lung disease, malaria and even the common cold can also help prevent and treat cancers because they fight against mitochondrial oxidative stress-a culprit in driving tumor growth.

16 Feb 2011

Partners, Luminex team up to discover novel biomarkers, develop clinical assays

Luminex Corporation announced today that it has teamed with Partners HealthCare toward the discovery of novel biomarkers and development of clinical assays.

From Luminex 16 Feb 2011

Study: Heart rate turbulence is linked with increased risk of death from cardiovascular disease

Abnormal heart rate turbulence is associated with an increased risk of heart disease death in otherwise low-risk older individuals, according to a study funded by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

15 Feb 2011

Almac's Director plans to speak on adaptive trial designs at CTS Europe conference

The Almac Group announced today that Graham Nicholls, Director of Biostatistics for Almac's Clinical Technologies business unit, will be speaking at the Clinical Trial Supply Europe conference held in Barcelona, Spain, 22-23 February 2011.

15 Feb 2011

Studies reveal markers for measuring ability of children with ADHD to control impulsive movements

Two research studies published today in Neurology®, the medical journal of the American Academy of Neurology, found markers for measuring the ability of children with Attention Deficit Hyperactivity Disorder (ADHD) to control impulsive movements, which may reveal insights into the neurobiology of ADHD, inform prognosis and guide treatments.

15 Feb 2011

OXiGENE, NCI/CTEP and GOG collaborate on ZYBRESTAT Phase 2 study in relapsed ovarian cancer

OXiGENE, Inc., a clinical-stage, biopharmaceutical company developing novel therapeutics to treat cancer and eye diseases, announced today that it has entered into a Cooperative Research and Development Agreement with the National Cancer Institute's (NCI) Cancer Therapy Evaluation Program (CTEP) to collaborate on the conduct of a randomized Phase 2 trial of ZYBRESTAT in combination with bevacizumab in patients with relapsed ovarian cancer.

14 Feb 2011

Novel technology to diagnose Alzheimer's disease before symptoms appear

UT Southwestern Medical Center scientists have helped develop a novel technology to diagnose Alzheimer's disease from blood samples long before symptoms appear.

14 Feb 2011

BD and UCLB enter agreement for development of new diagnostics for ovarian, breast cancer

UCL Business (UCLB), a wholly owned subsidiary of University College London (UCL), and BD (Becton, Dickinson and Company), a leading global medical technology company, announced today an agreement aimed at improving the early detection of ovarian and breast cancers to ultimately enable earlier and more effective treatment.

From BD (Becton, Dickinson and Company) 10 Feb 2011

Seaweed microsponges may help diagnose many diseases quickly, at far lower cost

Microsponges derived from seaweed may help diagnose heart disease, cancers, HIV and other diseases quickly and at far lower cost than current clinical methods. The microsponges are an essential component of Rice University's Programmable Bio-Nano-Chip (PBNC) and the focus of a new paper in the journal Small.

9 Feb 2011

Clinical Data reports $2.0 million revenue for third quarter 2011

Clinical Data, Inc. today announced operational and financial results for the third fiscal quarter ended December 31, 2010. The Company received approval from the U.S. Food and Drug Administration (FDA) of Viibryd™ for the treatment of adults with major depressive disorder (MDD) on January 21, 2011.

9 Feb 2011

Researchers find large variations in quality and safety across diabetes websites

Nearly one-half of U.S. adults who use the Internet participate in social networks. While these increasingly include health-focused networks, not much is known about their quality and safety. In one of the first formal studies of social networking websites targeting patients, researchers in the Children's Hospital Boston Informatics Program performed an in-depth evaluation of ten diabetes websites.

9 Feb 2011

Cardiac enzyme elevations following CABG surgery is associated with worse prognosis

Patients who underwent coronary artery bypass graft surgery and had elevated levels of the cardiac enzymes creatine kinase or troponin in the 24 hours following surgery had an associated intermediate and long-term increased risk of death, according to a study in the February 9 issue of JAMA.

9 Feb 2011

Aushon BioSystems enters diagnostic development collaboration with Peking University Cancer Hospital

Aushon BioSystems, Inc., a leading provider of multiplex immunoassay products and services announced that it has signed a letter of intent to enter into a diagnostic development collaboration with Peking University Cancer Hospital ("PUCH"), Beijing, China.

9 Feb 2011

USPTO issues patent for Metabolon's UHPLC/MSn-based analytical platform

Metabolon, the leader in metabolomics, biomarker discovery and analysis, announced today the grant of US Patent No. 7,884,318 entitled "Systems, Methods, and Computer-Readable Medium for Determining Composition of Chemical Constituents in a Complex Mixture".

8 Feb 2011

Almac opens analytical facility at new 240,000 sq. ft. North American Headquarters

Almac's new 240,000 sq. ft. North American Headquarters, built on 40 acres in Souderton, PA, north of Philadelphia is part of the Almac Group's integrated services solutions strategy. The new facility delivers full-service, integrated clinical packaging, drug supply management and technology solutions to pharmaceutical and biotech clients.

8 Feb 2011

Study identifies genetic variation linked with increased risk of major depression

Numerous studies have shown that the brain molecule neuropeptide Y (NPY) helps to restore calm after stressful events. A team of University of Michigan-led researchers has now found that people whose genes predispose them to produce lower levels of NPY are more responsive to negative stimuli in key brain circuits related to emotion - and are therefore less resilient in the face of stress and may be at higher risk for developing a major depressive disorder.

8 Feb 2011

CMD co-founder receives Prize4Life award for discovery of new ALS biomarker

Convergence Medical Devices (CMD) today announced that its co-founder, Dr. Seward Rutkove, Chief of the Division of Neuromuscular Disease at Beth Israel Deaconess Medical Center and Associate Professor of Neurology at Harvard Medical School, received Prize4Life's prestigious award for the discovery of a new biomarker for ALS (Amyotrophic Lateral Sclerosis), also known as Lou Gehrig's disease.

7 Feb 2011

British Journal of Dermatology publishes data on DermTech's new genomic assay for melanoma

DermTech International, a biotechnology company dedicated to bringing genomic medicine to dermatologists, today announced that the discovery data on its new genomic assay for melanoma have been published in the British Journal of Dermatology.

7 Feb 2011

Cholesterol efflux capacity may protect against heart disease: Study

The discovery that high levels of high-density lipoprotein cholesterol are associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

4 Feb 2011

Study: Pistachios may help reduce risk of heart disease

It's no coincidence that National Pistachio Day – February 26, 2011 – occurs during American Heart Month. Heart disease remains the leading cause of death in America, and promising nutrition research shows that pistachios are a heart healthy snack choice. In honor of American Heart Month, TheGreenNut.org is offering simple tips encouraging all Americans to go green for a healthy heart this February.

4 Feb 2011

Biomarker News and Research

Further Reading

Genetic proof for anti-cancer properties of antioxidants and autophagy inhibitors

Partners, Luminex team up to discover novel biomarkers, develop clinical assays

Study: Heart rate turbulence is linked with increased risk of death from cardiovascular disease

Almac's Director plans to speak on adaptive trial designs at CTS Europe conference

Studies reveal markers for measuring ability of children with ADHD to control impulsive movements

OXiGENE, NCI/CTEP and GOG collaborate on ZYBRESTAT Phase 2 study in relapsed ovarian cancer

Novel technology to diagnose Alzheimer's disease before symptoms appear

BD and UCLB enter agreement for development of new diagnostics for ovarian, breast cancer

Seaweed microsponges may help diagnose many diseases quickly, at far lower cost

Clinical Data reports $2.0 million revenue for third quarter 2011

Researchers find large variations in quality and safety across diabetes websites

Cardiac enzyme elevations following CABG surgery is associated with worse prognosis

Aushon BioSystems enters diagnostic development collaboration with Peking University Cancer Hospital

USPTO issues patent for Metabolon's UHPLC/MSn-based analytical platform

Almac opens analytical facility at new 240,000 sq. ft. North American Headquarters

Study identifies genetic variation linked with increased risk of major depression

CMD co-founder receives Prize4Life award for discovery of new ALS biomarker

British Journal of Dermatology publishes data on DermTech's new genomic assay for melanoma

Cholesterol efflux capacity may protect against heart disease: Study

Study: Pistachios may help reduce risk of heart disease

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