Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study reveals metabolic syndrome's impact on brain volume and cognitive function

Associations between metabolic syndrome (MetS) and cognitive and neuroimaging outcomes in dementia-free adults.

24 Jun 2024

Mindfulness meditation curbs gaming addiction by altering brain responses

Mindfulness meditation significantly reduces gaming cravings and addiction severity in adults with Internet Gaming Disorder. The study reveals decreased activation in brain regions associated with craving, such as the lentiform nuclei and medial frontal gyrus.

23 Jun 2024

UCF researcher further explores nanotech to improve cancer and disease detection

Early discovery of debilitating diseases such as cancer or dementia is critical in determining treatment and saving lives.

21 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

Evaluation of serum tumor markers as adjuncts in NSCLC management

A new research paper was published in Oncotarget's Volume 15 on June 13, 2024, entitled, "Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management."

20 Jun 2024

Noninvasive urine test enhances early detection of bladder cancer in patients with hematuria

One of the first signs of bladder cancer can be blood in the urine (hematuria). Investigators developed and analyzed the results of a streamlined and simplified DNA-based urine test to improve the accuracy of early detection of bladder cancer in patients with hematuria.

20 Jun 2024

Modified form of chemotherapy before and after surgery enhances survival in pancreatic cancer patients

Patients with pancreatic cancer who received chemotherapy both before and after surgery experienced longer survival rates than would be expected from surgery followed by chemotherapy, according to a new study from researchers at Yale Cancer Center (YCC) and Yale School of Medicine.

20 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals -; Mass Eye and Ear and Massachusetts General Hospital (MGH)-; reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

Proteins in blood may help to predict Parkinson’s disease up to seven years before the onset of motor symptoms

Researchers combined mass spectrometry-based proteomic phenotyping with machine learning to identify blood biomarkers in early Parkinson's disease.

20 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

Innovative bread formulation shows promise in preventing asthma

Brazilian researchers have developed functional bread with the potential to prevent asthma, a respiratory disorder responsible for some 350,000 hospitalizations per year in the SUS (Sistema Único de Saúde), the nation's public healthcare network.

17 Jun 2024

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

A recent review outlines the necessary factors for widespread implementation and interpretation of Alzheimer's disease blood-based biomarkers (BBMs) at the population level, emphasizing the potential for early detection and improved diagnosis.

14 Jun 2024

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in Microbiology Spectrum, a journal of the American Society for Microbiology.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Jun 2024

Biomarker News and Research

Further Reading

Study reveals metabolic syndrome's impact on brain volume and cognitive function

Mindfulness meditation curbs gaming addiction by altering brain responses

UCF researcher further explores nanotech to improve cancer and disease detection

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Evaluation of serum tumor markers as adjuncts in NSCLC management

Noninvasive urine test enhances early detection of bladder cancer in patients with hematuria

Modified form of chemotherapy before and after surgery enhances survival in pancreatic cancer patients

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

Proteins in blood may help to predict Parkinson’s disease up to seven years before the onset of motor symptoms

New research explores maternal influence on brain biomarkers

Innovative bread formulation shows promise in preventing asthma

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

UD researchers pioneer universal, economical method for proteomics sample preparation

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Breathing New Life into Diagnostics: Plasmion's SICRIT® Technology

Precision-guided treatment boosts outcomes in children with high-risk cancers

Host RNA incorporation linked to chronic hepatitis E infection

New brain connectivity model predicts dementia years before diagnosis

Surprising link between a diverse oral microbiome and better cognitive function in aging

eBook: Cellular Senescence eBook

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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