Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Potentially new biomarkers for Alzheimer's

Every aging baby boomer listens for the footsteps of Alzheimer's, and for good reason: It's estimated that 10 million American boomers will develop the disease. The need to develop preventative strategies, ideally long before Alzheimer's destructive, clinical symptoms appear, is critical.

19 Jul 2008

Fred Hutchinson awarded $7.6 million to research how genetic variations influence risk of common diseases

Researchers at Fred Hutchinson Cancer Research Center have received a $7.6 million, four-year grant from the National Human Genome Research Institute to better understand the genetic and biological roots of common diseases. The Hutchinson Center is one of four U.S. research institutes to receive grants totaling about $31 million toward this effort.

17 Jul 2008

Closing coal-fired power plants directly improves cognitive development in children

Closing coal-fired power plants can have a direct, positive impact on children's cognitive development and health according to a study released by the Columbia Center for Children's Environmental Health (CCCEH) at Columbia University's Mailman School of Public Health.

14 Jul 2008

Colorectal cancer screening rates still too low

Although colorectal cancer screening tests are proven to reduce colorectal cancer mortality, only about half of U.S. men and women 50 and older receive the recommended tests, according to a report in the July 2008 issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research.

14 Jul 2008

FA imaging, invented at U-M, measures metabolic stress in retina - serves as early warning of diabetes

A new vision screening device, already shown to give an early warning of eye disease, could give doctors and patients a head start on treating diabetes and its vision complications, a new study shows.

14 Jul 2008

New system pinpoints potential "biomarkers" of early forms of the disease

In order to provide the most effective treatments for cancer patients, it is essential to develop methods of sensitive and specific early detection of the disease. A team of scientists from the NIBRT Dublin-Oxford Glycobiology Laboratory at UCD has developed a system which aims to pinpoint potential "biomarkers" of early forms of the disease.

10 Jul 2008

Improving quantum dot synthesis

Materials researchers at the National Institute of Standards and Technology (NIST) have developed a simplified, low-cost process for producing high-quality, water-soluble quantum dots for biomedical applications.

9 Jul 2008

Protein found in immune cells may be a reliable marker for schizophrenia risk

Schizophrenia is a severe and complex psychiatric illness that affects about 1% of the population. Diagnosis currently relies on subjective clinical interviews and the assessment of ambiguous symptoms, which frequently leads to delayed diagnosis and treatment. As such, biomarkers that would indicate schizophrenia risk or onset would be extremely useful.

8 Jul 2008

Seven elevated biomarkers predict prostate cancer risk with 86.6 percent reliability

A simple blood test screening for a panel of biomarkers can accurately predict whether a patient who has had prostate cancer surgery will have a recurrence or spread of the disease.

26 Jun 2008

Faulty DNA repair could be a risk factor for lung cancer in nonsmokers

People who have never smoked but whose cells cannot efficiently repair environmental insults to DNA are at higher risk of developing lung cancer than those with effective genomic repair capability, according to researchers from the Department of Epidemiology at The University of Texas M. D. Anderson Cancer Center.

26 Jun 2008

Clinical Data secures European patent for key multi-drug resistance gene

Clinical Data, Inc. has announced that the European Patent Office has granted Patent No. 1232260 to Bernried, Germany-based Epidauros Biotechnologie AG, a wholly-owned subsidiary of Clinical Data, relating to the use of a genetic variant, or biomarker, of the gene MDR1 (also known as ABCB1), which encodes P-glycoprotein (PGP).

26 Jun 2008

Neurological assessment of older adults: A crystal ball to the future

Standard neurological exams of older adults are good predictors of future brain health and quality of life. These tests should become part of the physician's routine examination of older adults say faculty from the Indiana University Center for Aging Research in an editorial in the June 23, 2008 issue of the Archives of Internal Medicine.

24 Jun 2008

Neurological assessment of older adults should become routine examinations

24 Jun 2008

Seven biomarkers that may help pinpoint prostate cancer recurrence found

A simple blood test may help doctors better predict whether prostate cancer will recur or spread in patients who have undergone surgery for the disease, UT Southwestern Medical Center researchers have found.

24 Jun 2008

Early detection of Alzheimer's in the pipeline

A boost of $1.6 million for new research into Alzheimer's Disease for Australian scientists means that the early detection of the disease could well be in the pipeline.

19 Jun 2008

Discovery of new biomarkers for growth hormone - potential for detecting growth hormone abuse

Researchers have found potential new biomarkers for growth hormone, which they say could help the sports community in detecting growth hormone abuse. The results of the animal study will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco.

17 Jun 2008

Seven biomarkers found that predict with 86 percent accuracy prostate cancer recurrence

A simple blood test may help doctors better predict whether prostate cancer will recur or spread in patients who have undergone surgery for the disease, researchers at UT Southwestern Medical Center have found.

17 Jun 2008

Melanomas "run" in families - CDKN2A gene reveals why

When people know the results of genetic tests confirming they have inherited an increased risk of developing melanoma, they follow skin cancer screening recommendations more proactively-much like those who have already been diagnosed with the potentially deadly disease, according to results of a study completed at the University of Utah's Huntsman Cancer Institute. and published in the June issue of Cancer Epidemiology, Biomarkers & Prevention.

17 Jun 2008

Scientists identify proteins in mice that might act as biomarkers for growth hormone

Ohio University scientists have identified several proteins in mice that might act as biomarkers for growth hormone. The research could be the first step to finding a more reliable way to detect recombinant human growth hormone (rhGH), which some athletes and teenagers use illegally to boost muscle and reduce fat.

17 Jun 2008

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

In the first use of a framework allowing submission of a single application to the two agencies, the Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) worked together to allow drug companies to submit the results of seven new tests that evaluate kidney damage during animal studies of new drugs. The tests measure the levels of seven key proteins or "biomarkers" found in urine that can provide additional information about drug-induced damage to kidney cells, also known as renal toxicity.

15 Jun 2008

Biomarker News and Research

Further Reading

Potentially new biomarkers for Alzheimer's

Fred Hutchinson awarded $7.6 million to research how genetic variations influence risk of common diseases

Closing coal-fired power plants directly improves cognitive development in children

Colorectal cancer screening rates still too low

FA imaging, invented at U-M, measures metabolic stress in retina - serves as early warning of diabetes

New system pinpoints potential "biomarkers" of early forms of the disease

Improving quantum dot synthesis

Protein found in immune cells may be a reliable marker for schizophrenia risk

Seven elevated biomarkers predict prostate cancer risk with 86.6 percent reliability

Faulty DNA repair could be a risk factor for lung cancer in nonsmokers

Clinical Data secures European patent for key multi-drug resistance gene

Neurological assessment of older adults: A crystal ball to the future

Neurological assessment of older adults should become routine examinations

Seven biomarkers that may help pinpoint prostate cancer recurrence found

Early detection of Alzheimer's in the pipeline

Discovery of new biomarkers for growth hormone - potential for detecting growth hormone abuse

Seven biomarkers found that predict with 86 percent accuracy prostate cancer recurrence

Melanomas "run" in families - CDKN2A gene reveals why

Scientists identify proteins in mice that might act as biomarkers for growth hormone

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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