Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."

8 Feb 2024

Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

8 Feb 2024

Study suggests there may be specific pathways to adolescent depression that begin in the womb

Researchers investigated the relationship between prenatal maternal inflammation (PNMI) and depressive symptoms in their adolescent offspring.

8 Feb 2024

Immune cell networks key to success of personalized cancer treatment

Through an analysis of tumor samples collected over time from patients with advanced melanoma, a Ludwig Cancer Research study has identified a set of preexisting conditions in tumors that predict whether such patients are likely to respond to a personalized immunotherapy known as adoptive T cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL).

7 Feb 2024

New research facility at the University of Surrey could soon unlock the secrets of diseases

A new research facility at the University of Surrey could soon help society better understand various diseases or even help scientists trace nanoplastics through the bodies and cells of humans and animals.

5 Feb 2024

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

1 Feb 2024

New approach offers hope for regaining lost memories in Alzheimer's

While newly approved drugs for Alzheimer's show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory.

1 Feb 2024

Berry consumption shown to lower stress-related disease risk in US adults

The association between berry consumption and physiological dysregulation from stress responses.

1 Feb 2024

OMT could provide a viable, non-drug treatment for migraine headaches

New research by a New York Institute of Technology College of Osteopathic Medicine (NYITCOM) professor finds that osteopathic manipulative treatment (OMT) could provide a viable, non-drug treatment for migraine headaches.

31 Jan 2024

Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer’s Disease

Recipients of cadaver-derived pituitary growth hormone (c-hGH) developed biomarker changes in the realm of Alzheimer’s disease (AD).

31 Jan 2024

Vitamin D deficiency linked to increased dementia risk, supplements may help

Study in the UK Biobank cohort found vitamin D deficiency and insufficiency significantly increase the risk of dementia, Alzheimer's, and vascular dementia, with supplementation potentially reducing these risks.

30 Jan 2024

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."

30 Jan 2024

Primary care providers may be the key to accelerating delivery of emerging Alzheimer's treatments

There is substantial geographic variation across the U.S. health care system to diagnose and treat early-stage Alzheimer's disease with disease-modifying therapies, and engaging primary care providers in the effort may be a key to accelerating delivery of emerging new treatments, according to a new RAND report.

30 Jan 2024

Study reveals significant health benefits of golden berries in diabetic and obese rats

The effects of a Golden Berry (Physalis peruviana)-enriched diet on insulin resistance and obesity.

30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Bio-Techne Corporation (NASDAQ: TECH) today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Machine learning unlocks personalized approach to early ovarian cancer detection

For over three decades, a highly accurate early diagnostic test for ovarian cancer has eluded physicians.

29 Jan 2024

Common biomarker test could be misguiding treatment for some Black women with breast cancer

A common test used to decide whether breast cancer patients should get chemotherapy may be making bad recommendations for some Black women, leading them to forgo chemotherapy when it might have helped, according to new research from the University of Illinois Chicago.

29 Jan 2024

Subcutaneous nivolumab revolutionizes renal cell carcinoma care with faster, easier treatment

Subcutaneous injection of the immunotherapy nivolumab (brand name Opdivo) is noninferior to intravenous delivery and dramatically reduces treatment time in patients with renal cell carcinoma, as seen in the results of a large phase 3 clinical trial reported today at the 2024 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium in San Francisco, California.

29 Jan 2024

Interventions for mood show promise for the management of IBD in improving mental health, inflammation and disease outcomes

Researchers performed a meta-analysis to explore the impact of mood interventions on inflammatory disease activity in inflammatory bowel disease (IBD).

29 Jan 2024

Biomarker News and Research

Further Reading

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

Enzyme released by immune cells may play role in depression

Study suggests there may be specific pathways to adolescent depression that begin in the womb

Immune cell networks key to success of personalized cancer treatment

New research facility at the University of Surrey could soon unlock the secrets of diseases

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

New approach offers hope for regaining lost memories in Alzheimer's

Berry consumption shown to lower stress-related disease risk in US adults

OMT could provide a viable, non-drug treatment for migraine headaches

Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer’s Disease

Vitamin D deficiency linked to increased dementia risk, supplements may help

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

Primary care providers may be the key to accelerating delivery of emerging Alzheimer's treatments

Study reveals significant health benefits of golden berries in diabetic and obese rats

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

Machine learning unlocks personalized approach to early ovarian cancer detection

Common biomarker test could be misguiding treatment for some Black women with breast cancer

Subcutaneous nivolumab revolutionizes renal cell carcinoma care with faster, easier treatment

Interventions for mood show promise for the management of IBD in improving mental health, inflammation and disease outcomes

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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