Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Real-time monitor can detect SARS-CoV-2 in indoor air within 5 minutes

Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses.

10 Jul 2023

Abnormal cortical folding linked to major depressive disorder

Major depressive disorder (MDD) is a complex and debilitating metal illness. Given its complex and widespread nature, MDD has been a subject of intense medical research.

10 Jul 2023

Study uncovers three previously unknown membrane proteins in ovarian cancer

A study led by Nagoya University in Japan has identified three previously unknown membrane proteins in ovarian cancer.

7 Jul 2023

Improved diagnosis of occlusion myocardial infarction using novel machine learning tools

Machine learning models were developed to diagnose heart attacks in patients with no ST-elevation on their initial electrocardiogram, outperforming clinicians and improving accuracy. The models' risk score enhanced diagnostic accuracy and reclassified chest pain patients, providing mechanistic links to heart injury.

6 Jul 2023

OCT imaging method can improve diagnosis of multiple sclerosis

A study conducted by researchers from the Department of Neurology at MedUni Vienna and University Hospital Vienna has demonstrated for the first time that diagnosis of multiple sclerosis (MS) can be significantly improved by additionally measuring the thickness of retinal layers in the eye.

6 Jul 2023

New therapy to mitigate fragile X syndrome may be on the horizon

An antisense therapy developed by Joel D. Richter, PhD, Sneha Shah, PhD, and Jonathan K. Watts, PhD, at UMass Chan Medical School and Elizabeth Berry-Kravis, MD, PhD, at RUSH University Medical Center, restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome.

5 Jul 2023

Biomarker found in urine could help diagnose acute tubulointerstitial nephritis

In a study led by Johns Hopkins Medicine, in collaboration with Yale School of Medicine, researchers have identified a biomarker found via a simple urine test that can be used to diagnose acute tubulointerstitial nephritis (AIN), a medical condition that causes inflammation of the kidneys and can lead to acute kidney injury (AKI) — a sudden loss of kidney function.

5 Jul 2023

Scientists identify blood proteins that may predict Type 1 diabetes

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

4 Jul 2023

New biomarker for major depressive disorder identified

In appearance, the human brain's outermost layer, called the cortex, is a maze of tissue folds. The peaks or raised surfaces of these folds, called gyri, play an important role in the proper functioning of the brain.

4 Jul 2023

Smoking and HPV found to increase risk of head and neck cancer

Tobacco smoking and human papillomavirus (HPV) are both well-known risk factors for head and neck cancer, but there is ample evidence to show they can interact to increase still further the risk of contracting the disease, according to a study by scientists at the University of São Paulo (USP) in Brazil and the University of Chile.

3 Jul 2023

Researchers validate first-ever AI biomarker for ADT benefit in prostate cancer

Data from a new study published in NEJM Evidence shows promise for personalized use of short-term ADT in men with predominantly intermediate-risk prostate cancer.

30 Jun 2023

Using the power of machine learning to develop a predictive model of rumination

Our minds often get trapped in repetitive thoughts, such as past mistakes, regrets, insecurities, or unresolved conflicts.

29 Jun 2023

Scientists identify altered proteins that predict islet autoimmunity

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

29 Jun 2023

UH and CWRU research teams win Collaborative Science Pilot Awards

Three University Hospitals (UH) and Case Western Reserve University School of Medicine research teams recently received Collaborative Science Pilot Awards. The teams each received $50,000, funded by both institutions.

28 Jun 2023

Multiple subtypes of major depressive disorder identified using brain imaging

Major depressive disorder (MDD) is not only among the most common mental illnesses, affecting over 8% of Americans, but it is also extremely variable from one person to another.

27 Jun 2023

Is there an association between muscle-building supplements and DNA damage in resistance training practitioners?

A recent study investigated whether muscle-building supplements are associated with DNA damage in individuals practicing resistance training.

27 Jun 2023

Novel computational tool helps analyze complex genetic regions

GeneDx (Nasdaq: WGS), a leader in delivering improved health outcomes through genomic and clinical insights, today published a paper in Nature Methods, titled "Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes," in which researchers developed a new computational tool, the PanGenome Research-Tool Kit (PGR-TK), for scalable analysis of clinically relevant genes that were previously too complex to analyze.

27 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

Personalized dosing improves outcomes for men with metastatic castration-resistant prostate cancer

By monitoring early-response biomarkers in men undergoing 177Lu-PSMA prostate cancer treatment, physicians can personalize dosing intervals, significantly improving patient outcomes.

26 Jun 2023

Study finds link between environmental chemical exposure and thyroid problems in women with fertility issues

A study led by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, reveals multiple associations between the presence of phenol biomarkers and altered thyroid hormone measurements among women seeking fertility care.

26 Jun 2023

Biomarker News and Research

Further Reading

Real-time monitor can detect SARS-CoV-2 in indoor air within 5 minutes

Abnormal cortical folding linked to major depressive disorder

Study uncovers three previously unknown membrane proteins in ovarian cancer

Improved diagnosis of occlusion myocardial infarction using novel machine learning tools

OCT imaging method can improve diagnosis of multiple sclerosis

New therapy to mitigate fragile X syndrome may be on the horizon

Biomarker found in urine could help diagnose acute tubulointerstitial nephritis

Scientists identify blood proteins that may predict Type 1 diabetes

New biomarker for major depressive disorder identified

Smoking and HPV found to increase risk of head and neck cancer

Researchers validate first-ever AI biomarker for ADT benefit in prostate cancer

Using the power of machine learning to develop a predictive model of rumination

Scientists identify altered proteins that predict islet autoimmunity

UH and CWRU research teams win Collaborative Science Pilot Awards

Multiple subtypes of major depressive disorder identified using brain imaging

Is there an association between muscle-building supplements and DNA damage in resistance training practitioners?

Novel computational tool helps analyze complex genetic regions

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Personalized dosing improves outcomes for men with metastatic castration-resistant prostate cancer

Study finds link between environmental chemical exposure and thyroid problems in women with fertility issues

Breaking Barriers: ANDYSMANCLUB's Fight for Men's Mental Health on World Mental Health Day

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

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