Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

miR 155 overexpression can lead to cancer

Scientists in the Ohio State University Comprehensive Cancer Center say that just one, single, malfunctioning microRNA is sufficient to cause cancer in mice.

18 Apr 2006

Placental growth factor may help body repair heart attack damage

Heart attack patients produce higher levels of a natural substance in the body that plays a role in the growth of new blood vessels and this over-expression of placental growth factor (PlGF) may help reduce damage to the heart muscle

17 Apr 2006

Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6

A novel growth factor significantly improves the ability of specialized stem cells derived from human fat to be transformed into cartilage cells, according to Duke University Medical Center and Pratt School of Engineering researchers.

16 Apr 2006

Researchers suggest drug could block metastasis or reduce pain for bone cancer patients

An international research team has identified what may be a critical molecule in the ability of tumours to metastasize -- or spread -- into bone.

13 Apr 2006

New insights into how anti-rejection drug daclizumab (Zenapax) helps MS patients

A research team led by the University of Cincinnati's Bibiana Bielekova, MD, report new insights into the role of the MS drug daclizumab (Zenapax) in the Proceedings of the National Academy of Sciences.

11 Apr 2006

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

A study led by researchers from the Howard Hughes Medical Institute has found that dasatinib provides significant benefit in chronic myeloid leukemia (CML) patients resistant to Gleevec. (imatinib), according to a study presented during the 97th Annual Meeting of the American Association for Cancer Research.

11 Apr 2006

Single dose of stem cells produce robust behavioral recovery in animal models for stroke, cerebral palsy

A single dose of adult donor stem cells given to animals that have neurological damage similar to that experienced by adults with a stroke or newborns with cerebral palsy can significantly enhance recovery from these types of injuries, researchers say.

11 Apr 2006

MPD Foundation funds research for incurable blood disorders

The Myeloproliferative Disorders Foundation has awarded $750,000 to establish the MPD Research Alliance, a collaboration of the University of Illinois at Chicago, Harvard Medical School and Mayo Clinic to accelerate drug development for incurable, progressive bone marrow disorders.

11 Apr 2006

Adult stem cells can be used to make new tendon or ligament tissue

Weekend athletes who overexert themselves running or playing basketball may one day reap the benefits of research at the Hebrew University of Jerusalem that shows that adult stem cells can be used to make new tendon or ligament tissue.

4 Apr 2006

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Inflammation, cartilage and bone erosions, joint destruction--that's the typical progression of arthritis and most rheumatic diseases.

4 Apr 2006

St. Jude develop relatively simple and inexpensive test for acute lymphoblastic leukemia

Investigators at St. Jude Children's Research Hospital have developed a relatively simple and inexpensive test that identifies children with acute lymphoblastic leukemia (ALL) who have responded well enough to their first round of chemotherapy that they might be successfully treated with a much less aggressive follow-up treatment.

3 Apr 2006

Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas

Inactivation of a "tumor suppressor" gene could be a major cause of a class of blood cancers called diffuse large B-cell lymphomas, reports a team of researchers at the Weill Medical College of Cornell University.

30 Mar 2006

Novel therapy for chronic graft-versus-host disease

A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants.

28 Mar 2006

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Dana-Farber researchers found that rituximab reduced the severity of chronic graft-versus-host disease (GVHD) in 70 percent of the study participants.

27 Mar 2006

Cell therapy slows progression of metachromatic leukodystrophy

In an important discovery, scientists have demonstrated that the progression of a type of genetic brain disease is slowed and symptoms are improved in mice that received cell transplants.

23 Mar 2006

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

A team of cell biologists, toxicologists and molecular bioscientists at UC Davis has published a study connecting thimerosal with disruptions in antigen-presenting cells known as dendritic cells obtained from mice.

22 Mar 2006

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

Japanese researchers have found a piece of the "missing link" about how bone marrow stromal cells restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders, according to a study in the March issue of the Journal of Nuclear Medicine.

21 Mar 2006

Scientists identify microRNAs that appear to play a role in the development of platelets

Scientists have identified a handful of microRNAs (miRNAs) that appear to play a significant role in the development of platelets - blood cells critical to the body's ability to form clots following an injury.

21 Mar 2006

Study offers piece of missing link needed in understanding receptor function possibly providing safe, ethical source for replacing brain cells

19 Mar 2006

New understanding of the critical molecular factors that permit viruses to jump from one species to another

Researchers studying strains of a lethal canine virus and a related human virus have determined why the canine virus was able to spread so quickly from cats to dogs, and then from sick dogs to healthy dogs.

19 Mar 2006

Bone Marrow News and Research

Further Reading

miR 155 overexpression can lead to cancer

Placental growth factor may help body repair heart attack damage

Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6

Researchers suggest drug could block metastasis or reduce pain for bone cancer patients

New insights into how anti-rejection drug daclizumab (Zenapax) helps MS patients

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

Single dose of stem cells produce robust behavioral recovery in animal models for stroke, cerebral palsy

MPD Foundation funds research for incurable blood disorders

Adult stem cells can be used to make new tendon or ligament tissue

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

St. Jude develop relatively simple and inexpensive test for acute lymphoblastic leukemia

Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas

Novel therapy for chronic graft-versus-host disease

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Cell therapy slows progression of metachromatic leukodystrophy

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

Scientists identify microRNAs that appear to play a role in the development of platelets

Study offers piece of missing link needed in understanding receptor function possibly providing safe, ethical source for replacing brain cells

New understanding of the critical molecular factors that permit viruses to jump from one species to another

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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