Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

FDA grants orphan drug designation for Edison's EPI-743 to treat inherited mitochondrial diseases

Edison Pharmaceuticals, Inc. announced today the United States Food and Drug Administration has granted orphan drug designation to EPI-743 for treatment of inherited mitochondrial respiratory chain diseases.

8 Jun 2011

SPI and Neuralstem sign licensing agreement for major depression drug, NSI-189

Neuralstem, Inc. announced that it has signed an exclusive agency licensing agreement with Summit Pharmaceuticals International Corporation, of Tokyo, Japan (SPI), a wholly owned subsidiary of Sumitomo Corporation Group.

8 Jun 2011

Geron's GRNOPC1 Phase 1 trial results on spinal cord injury presented at international conferences

Geron Corporation today announced two presentations on the company's ongoing Phase 1 clinical trial of the human embryonic stem cell-based therapy, GRNOPC1, in patients with spinal cord injury.

7 Jun 2011

IsoRay completes Iotrex license agreement with Dr. Reddy's

IsoRay, Inc. announced today that it has completed a license agreement with Dr. Reddy's Laboratories for exclusive worldwide licensing rights to Iotrex, a liquid iodine radiation, for use in brain cancer treatment.

7 Jun 2011

Study provides epidemiology of fatal occupational traumatic brain injury in the U.S.

Although traumatic brain injury (TBI) is one of the leading causes of death in the United States, work-related TBI has not been well documented. In a study published in the July issue of the American Journal of Preventive Medicine, researchers describe the epidemiology of fatal TBI in the US workplace between 2003 and 2008.

7 Jun 2011

AMPYRA ER Tablets improve walking ability in patients with multiple sclerosis

Acorda Therapeutics, Inc. today announced an analysis of pooled clinical trial results showed patients who were responders to AMPYRA (dalfampridine) Extended Release Tablets, 10 mg demonstrated clinically relevant improvements in walking ability as measured by patient self-report on the 12-Item Multiple Sclerosis Walking Scale (MSWS-12), regardless of either their baseline Expanded Disability Status Scale (EDSS) score or baseline walking speed.

7 Jun 2011

Celgene announces ABRAXANE plus gemcitabine, bevacizumab phase II trial data on breast cancer

Celgene International Sàrl today announced that results from an investigator-initiated phase II study of ABRAXANE, gemcitabine and bevacizumab as first-line treatment in metastatic breast cancer were presented at the 2011 American Society of Clinical Oncology Annual Meeting in Chicago, IL.

7 Jun 2011

Study finds consistent link between Parkinson's disease and melanoma

An analysis of several studies shows that people with Parkinson's disease have a significantly higher risk of melanoma, the most dangerous type of skin cancer and the leading cause of death from skin diseases.

7 Jun 2011

Consumption of high-fat food causes more insulin to be released by the pancreas and leads to obesity

Fat-rich food makes you fat. Behind this simple equation lie complex signalling pathways, through which the neurotransmitters in the brain control the body's energy balance.

7 Jun 2011

EC approves Biogen Idec's AVONEX PEN to treat multiple sclerosis

Biogen Idec announced today that the European Commission (EC) has granted approval to AVONEX PEN for patients with relapsing multiple sclerosis (MS) and patients who have had a single demyelinating event.

7 Jun 2011

Pennsylvania reports first detection of West Nile encephalitis in Greene County

Pennsylvania has reported its earliest detection of a West Nile virus-carrying mosquito since testing began in 2000, the Department of Environmental Protection said today. The first detection of 2011 was a mosquito collection in Morgan Township, Greene County, on May 17.

7 Jun 2011

Symphogen's Sym004 Phase 1 trial data on advanced solid tumors presented at ASCO 2011

Symphogen announced today preliminary primary endpoint data on 12 of 20 patients enrolled in the first Phase 1 clinical trial with their lead cancer compound, Sym004.

7 Jun 2011

Manhattan acquires Senior Scientific

In a move to accelerate applications of a novel cancer detection and treatment technology, Manhattan Scientifics today announced that it has acquired all of Senior Scientific, LLC and its affiliate Scientific Nanomedicine Inc.

7 Jun 2011

Flaxseed of no use in menopausal hot flashes: Study

Flaxseed has been the latest agent that has been tried in treating menopausal hot flashes and it is seen that it does not reduce the incidence of the unpleasant symptoms.

7 Jun 2011

Mind-body dissonance prompts the brain to break normal cognitive boundaries

Think of the old saying, "grin and bear it." Can forcing a smile really have a positive impact on how people see the world, even to the point of becoming more open-minded? According to new research from the Kellogg School of Management at Northwestern University, the answer is yes.

6 Jun 2011

FDA grants Pathway marketing clearance for JETSTREAM Navitus revascularization catheter for PVD

Pathway Medical Technologies, Inc, an innovator of endovascular treatments for peripheral vascular disease (PVD), announced today that the U.S. Food and Drug Administration (FDA) has granted the company 510(k) clearance to market JETSTREAM Navitus, an enhanced revascularization catheter for the treatment of PVD.

6 Jun 2011

Positive data from Biogen Idec's AVONEX clinical trial on multiple sclerosis presented at CMSC 2011

Biogen Idec today announced the findings from a randomized, multicenter, dose-blinded clinical trial that evaluated the effect of AVONEX dose titration, or gradual dose escalation, on flu-like symptoms associated with the therapy.

6 Jun 2011

Light exposure can enhance brain's visual circuits

Any parent knows that newborns still have a lot of neurological work to do to attain fully acute vision. In a wide variety of nascent animals, genes provide them with only a rough wiring plan and then leave it to the developing nervous system to do its own finish work.

6 Jun 2011

Researchers discover a peptide that short circuits chronic pain pathway

Researchers at the Indiana University School of Medicine have discovered a peptide that short circuits a pathway for chronic pain. Unlike current treatments this peptide does not exhibit deleterious side effects such as reduced motor coordination, memory loss, or depression, according to an article in Nature Medicine posted online June 5, 2011.

6 Jun 2011

Positive interim results from CTI's OPAXIO-TMZ phase II trial on malignant brain tumors presented at ASCO

Cell Therapeutics, Inc. announced encouraging interim results of a phase II clinical study of OPAXIO combined with temozolomide and radiotherapy in patients with newly diagnosed high-grade malignant brain tumors.

6 Jun 2011

Brain News and Research

Further Reading

FDA grants orphan drug designation for Edison's EPI-743 to treat inherited mitochondrial diseases

SPI and Neuralstem sign licensing agreement for major depression drug, NSI-189

Geron's GRNOPC1 Phase 1 trial results on spinal cord injury presented at international conferences

IsoRay completes Iotrex license agreement with Dr. Reddy's

Study provides epidemiology of fatal occupational traumatic brain injury in the U.S.

AMPYRA ER Tablets improve walking ability in patients with multiple sclerosis

Celgene announces ABRAXANE plus gemcitabine, bevacizumab phase II trial data on breast cancer

Study finds consistent link between Parkinson's disease and melanoma

Consumption of high-fat food causes more insulin to be released by the pancreas and leads to obesity

EC approves Biogen Idec's AVONEX PEN to treat multiple sclerosis

Pennsylvania reports first detection of West Nile encephalitis in Greene County

Symphogen's Sym004 Phase 1 trial data on advanced solid tumors presented at ASCO 2011

Manhattan acquires Senior Scientific

Flaxseed of no use in menopausal hot flashes: Study

Mind-body dissonance prompts the brain to break normal cognitive boundaries

FDA grants Pathway marketing clearance for JETSTREAM Navitus revascularization catheter for PVD

Positive data from Biogen Idec's AVONEX clinical trial on multiple sclerosis presented at CMSC 2011

Light exposure can enhance brain's visual circuits

Researchers discover a peptide that short circuits chronic pain pathway

Positive interim results from CTI's OPAXIO-TMZ phase II trial on malignant brain tumors presented at ASCO

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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