Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Genentech's Avastin, chemotherapy Phase III combination study data on ovarian cancer presented at ASCO

Genentech, a member of the Roche Group, today announced results from OCEANS, a Phase III study evaluating Avastin (bevacizumab) in combination with chemotherapy followed by the continued use of Avastin alone in women with previously treated (recurrent) platinum-sensitive ovarian cancer.

6 Jun 2011

Weight loss following bariatric surgery may reduce risk of Alzheimer's

Obesity is a risk factor for Alzheimer's disease, but weight loss due to bariatric surgery may reduce the risk of this common dementia, a new study suggests. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

Bristol-Myers Squibb's second YERVOY Phase 3 trial on metastatic melanoma meets primary endpoint

Bristol-Myers Squibb Company today announced results from a second Phase 3 randomized, double blind study demonstrating that YERVOY (ipilimumab) prolonged the lives of patients with metastatic melanoma.

6 Jun 2011

Anti-ghrelin vaccine decreases food intake and increases calorie burning in mice

A new therapeutic vaccine to treat obesity by suppressing the appetite-stimulating hormone ghrelin decreases food intake and increases calorie burning in mice, a new study finds. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

Positive results from Plexxikon's vemurafenib Phase 2 and 3 trial against metastatic melanoma

Plexxikon Inc., a member of the Daiichi Sankyo Group, today announced efficacy and safety data from the BRIM3 trial, a large, randomized, multi-center Phase 3 clinical study of vemurafenib in patients with previously untreated metastatic melanoma with the BRAFV600 mutation.

6 Jun 2011

DFG to form new collaborative research centers as of 1 July 2011

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish 21 new Collaborative Research Centres (CRCs) as of 1 July 2011. This was decided by the relevant Grants Committee at its spring meeting in Bonn.

4 Jun 2011

Scientists find way to protect kidney from cancer drug toxicity

Scientists may have a way to make the powerful cancer drug cisplatin less toxic to the kidneys and more effective against some cancers.

4 Jun 2011

Results from HSPPC-96 Phase 2 study against recurrent gliobastoma presented at ASCO 2011

In data presented at The American Society of Clinical Oncology (ASCO) Annual Meeting, cancer researchers found that the brain tumor vaccine HSPPC-96 for treating recurrent gliobastoma (GBM) has a favorable safety profile and extends survival by two to three times more than the current median survival rate.

4 Jun 2011

Researchers develop new technology to detect neurological symptoms associated with epileptic seizure

Tiny electrodes have been coated with a drug-loaded polymer in an attempt to design an implant capable of detecting a number of neurological symptoms, such as those associated with an epileptic seizure, and treating them simultaneously.

4 Jun 2011

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Atherosclerosis is the most common cause of cardiovascular disease, and results from chronic inflammation of arterial vessel walls. An international collaboration led by Professor Christian Weber of Ludwig-Maximilians-Universität (LMU) in Munich and Privatdozentin Alma Zernecke of Würzburg University now shows that dendritic cells stimulate this process by derailing a mechanism that normally acts as a brake on immune reactions.

4 Jun 2011

Researcher to evaluate new approach for treatment of triple-negative breast cancer

A multicenter clinical trial led by a researcher at the University of Maryland Marlene and Stewart Greenebaum Cancer Center will evaluate a new approach to treat triple-negative breast cancer, an often-aggressive type of cancer that is more common among African-Americans and young women.

4 Jun 2011

Brown University researchers develop 2-D maps of neural circuitry in human brain

Medical imaging systems allow neurologists to summon 3-D color renditions of the brain at a moment's notice, yielding valuable insights. But sometimes there can be too much detail; important elements can go unnoticed.

4 Jun 2011

Study affirms effectiveness of palliative care discussions before LVAD surgery

For patients with severe heart failure, an implanted mechanical pump known as a Left Ventricular Assist Device can be a life-sustaining treatment. Even though the technology involves risks, few patients and their families tend to talk explicitly about the "what ifs" before surgery takes place.

4 Jun 2011

Survival rates of wealthier patients with glioblastoma are longer than poorer patients

Survival rates of wealthier patients and those younger than 70 with glioblastoma, the most common and aggressive malignant brain tumor, have improved since 2000, whereas rates for those living in poorer areas and older than 70 have remained stagnant, according to an abstract being presented at the American Society of Clinical Oncology annual meeting in Chicago by Thomas Jefferson University Hospital researchers on Saturday, June 4.

4 Jun 2011

Maryland researchers deny link between cell phone radiation and brain cancer

University of Maryland researchers in the A. James Clark School of Engineering have expressed concerns regarding the validity of recent findings announced in the Journal of the American Medical Association and a World Health Organization panel suggesting that radiation from cell phones may be carcinogenic.

4 Jun 2011

SBRT is effective for patients with low-to-intermediate-risk prostate cancer: Researchers

In a multicenter clinical trial, UT Southwestern Medical Center researchers have found that higher doses of stereotactic radiation therapy requiring fewer treatments are safe and effective for patients with low-to-intermediate-risk prostate cancer.

4 Jun 2011

Consumer groups, market experts support repeal of Medicare bidding program

Providers of home medical equipment and services in Oregon support H.R. 1041, a bipartisan bill in Congress that would repeal the controversial Medicare "competitive" bidding program for certain medically required equipment and services used at home.

4 Jun 2011

Decreasing iron-storing protein expression can enhance action of brain cancer therapy: Researchers

Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers.

4 Jun 2011

Roche, Bristol-Myers Squibb to evaluate YERVOY and vemurafenib treatment for metastatic melanoma

Bristol-Myers Squibb Company announced today it has entered in to a clinical collaboration agreement with Roche to evaluate the utility of Bristol-Myers Squibb's CTLA-4 inhibitor, YERVOY (ipilimumab), in combination with Roche's investigational oral BRAF inhibitor, vemurafenib, in treating patients with a specific type of metastatic melanoma.

4 Jun 2011

Research in progress for novel protein kinase inhibitors: GEN

Biotech scientists are working on novel protein kinase inhibitors that are targeting a host of conditions ranging from atherosclerosis to neurodegenerative diseases, reports Genetic Engineering & Biotechnology News.

4 Jun 2011

Brain News and Research

Further Reading

Genentech's Avastin, chemotherapy Phase III combination study data on ovarian cancer presented at ASCO

Weight loss following bariatric surgery may reduce risk of Alzheimer's

Bristol-Myers Squibb's second YERVOY Phase 3 trial on metastatic melanoma meets primary endpoint

Anti-ghrelin vaccine decreases food intake and increases calorie burning in mice

Positive results from Plexxikon's vemurafenib Phase 2 and 3 trial against metastatic melanoma

DFG to form new collaborative research centers as of 1 July 2011

Scientists find way to protect kidney from cancer drug toxicity

Results from HSPPC-96 Phase 2 study against recurrent gliobastoma presented at ASCO 2011

Researchers develop new technology to detect neurological symptoms associated with epileptic seizure

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Researcher to evaluate new approach for treatment of triple-negative breast cancer

Brown University researchers develop 2-D maps of neural circuitry in human brain

Study affirms effectiveness of palliative care discussions before LVAD surgery

Survival rates of wealthier patients with glioblastoma are longer than poorer patients

Maryland researchers deny link between cell phone radiation and brain cancer

SBRT is effective for patients with low-to-intermediate-risk prostate cancer: Researchers

Consumer groups, market experts support repeal of Medicare bidding program

Decreasing iron-storing protein expression can enhance action of brain cancer therapy: Researchers

Roche, Bristol-Myers Squibb to evaluate YERVOY and vemurafenib treatment for metastatic melanoma

Research in progress for novel protein kinase inhibitors: GEN

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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