Bronchopulmonary Dysplasia News and Research

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New noninvasive ventilation strategy benefits preterm infants with neonatal ARDS

Preterm infants with respiratory distress syndrome (RDS) face heightened risks of death, critical illness, and prolonged hospitalization, particularly if they progress to develop acute respiratory distress syndrome.

1 May 2019

Mayo Clinic study identifies potential new drug therapy for liver diseases

Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers.

22 Mar 2019

New clinical practice guideline on home oxygen therapy for children

The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy for children. The guideline appears in the Feb. 1 edition of the Society's American Journal of Respiratory and Critical Care Medicine.

4 Feb 2019

Caffeine therapy benefits developing brains of premature babies

For many, starting the day off with caffeine from a cup of coffee is a must. In neonatal intensive care units, or NICUs, premature babies born under 29 weeks are given a daily dose of caffeine to ensure the best possible start to life.

12 Dec 2018

Innovative inhalation system to treat premature babies with lung diseases

Premature babies who are born before their lungs have finished maturing often suffer from a lack of surfactant - a substance necessary for lung development.

3 Dec 2018

Research provides new insights about gender differences in airway disease risk

Human airways already demonstrate gender-based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in life, a research team reports in a paper published online April 3, 2018, in Scientific Reports.

6 Apr 2018

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Extremely low birth-weight babies are at risk for a chronic lung disease called bronchopulmonary dysplasia, or BPD.

9 Mar 2018

Length of stay in ICU may have impact on preterm babies’ behavior

A study conducted by researchers at the University of São Paulo's Ribeirão Preto School of Medicine in Brazil, with support from the Sao Paulo Research Foundation - FAPESP , indicates that length of stay in the ICU is the factor that best explains some preterm babies' behavioral problems relating to emotional regulation, regardless of the degree of prematurity and the presence of bronchopulmonary dysplasia and retinopathy of prematurity (ROP).

30 Nov 2017

Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants

Researchers at Drexel University have revealed that inhibiting the micro-RNA miR-34a significantly reduces bronchopulmonary dysplasia (BPD) in mice.

27 Oct 2017

Study sheds light on the mechanism of lung damage in premature babies

The lungs are one of the last organs to undergo full maturation in a baby's body. Children that are born very prematurely do not have fully developed lungs, and are therefore more susceptible to associated complications.

30 Sep 2017

Preemies treated with caffeine have better lung function in mid-childhood, study finds

Premature babies treated with caffeine have better lung function in mid-childhood than preemies not treated with caffeine, according to a randomized controlled trial published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

14 Jul 2017

Biomarker may predict death or poor pulmonary outcomes in extremely preterm infants

Tests of cells collected from the umbilical cord blood vessel walls at birth can predict death or poor pulmonary outcomes in extremely preterm infants, say researchers at the University of Alabama at Birmingham.

22 May 2017

Growth factors in cord blood may help identify preemies at risk for fatal lung disease

Findings published in the Journal of Pediatrics describe growth factors in cord blood that may identify premature infants at risk for bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) – an often fatal lung disease in which the vessels carrying blood from the heart to the lungs become narrowed and dysfunctional.

6 Apr 2017

Omega-3 fats fail to reduce risk of chronic lung disease in pre-term babies, study finds

THE long-held belief that Omega-3 fats can help reduce chronic lung disease in pre-term babies has been debunked by researchers.

31 Mar 2017

Steroid treatment linked to increased risk of retinopathy in very low birth weight infants

Because of the beneficial effect of corticosteroids on lung function, especially in infants who are ventilator dependent, corticosteroids are, at times, administered to very low birth weight neonates to treat established or evolving lung disease. However, it has long been suspected that steroids may have negative neurodevelopmental effects on very premature infants.

16 Aug 2016

Disordered airway microbiome at birth may be linked to severe neonatal lung disease

In contrast to the general belief that the airways of an infant are sterile until after birth, University of Alabama at Birmingham researchers and colleagues have found that the infant airway is already colonized with bacteria or bacterial DNA when a baby is born -- and this is true for infants born as early as 24 weeks gestation.

5 Aug 2016

Study offers new hope for preventing chronic lung disease in premature infants

By triggering a process called autophagy -- in which cells literally engulf their own insides --researchers from Drexel University and Yale University were able to decrease lung injury in mice that were exposed to high concentrations of oxygen.

20 Jul 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016

Steroid use in late preterm delivery can reduce rate of neonatal respiratory complications

Current recommendations are for all women who go into labor prior to 34 weeks gestation to be given antenatal corticosteroids (betamethasone) to help mature the baby's lungs. However, many babies born in the late preterm period - between 34 and 36 weeks gestation - require respiratory support at birth.

4 Mar 2016

Using corticosteroids before late preterm delivery reduces respiratory complications in babies

A multicenter clinical trial led by researchers at Columbia University Medical Center and NewYork-Presbyterian has found that the use of corticosteroids in mothers at risk for late preterm delivery significantly reduced the incidence of severe respiratory complications in their babies.

5 Feb 2016