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Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers discussed studies that explored T-cell immunity induced by SARS-CoV-2 infection and COVID-19 vaccination in cancer patients, individuals with HIV, and recipients of solid organ transplants.

8 Feb 2023

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

Researchers reviewed the impact of endometrial microbiota on immune tolerance during pregnancy.

8 Feb 2023

The nature of the immune responses induced by various COVID-19 vaccines developed using different platforms and formulations

Researchers reviewed existing achievements and shortcomings in SARS-CoV-2 vaccine platforms, as well as future-generation vaccine considerations.

7 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

Analysis of rebound virus suggests two separate reservoirs of latent HIV in patients

When people living with HIV take antiviral therapy (ART), their viral loads are driven so low that a standard blood test cannot detect the virus.

1 Feb 2023

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Researchers investigated the CAMCI strategy as an immunotherapeutic option for inflammatory bowel disease.

31 Jan 2023

Study suggests robust lung mucosal immunity against SARS-CoV-2 can be better achieved through hybrid immunity, as opposed to peripheral vaccination alone

Researchers characterized immunological responses by pulmonary mucosal tissues post-COVID-19 vaccination and/or SARS-CoV-2 infection, to assess the impact of hybrid immune protection on the durability of mucosal immunological responses.

30 Jan 2023

Data demonstrates SARS-CoV-2 Omicron XBB.1.5 substantially escapes NAb responses after bivalent mRNA boosting

Researchers reported that the SARS-CoV-2 Omicron XBB.1.5 variant evades neutralizing response elicited by bivalent vaccine boosters.

25 Jan 2023

Researchers use multiplexed 3D imaging to perform molecular and morphological assessments of colorectal cancers

Researchers used multiplexed and three-dimensional imaging with machine-based learning and spatial statistics to perform molecular and morphological assessments of colorectal cancers (CRC).

24 Jan 2023

Dietary plant sugar promotes antitumor immunity and enhances the efficacy of immunotherapy

Immunotherapies have improved outcomes of many patients with cancer, including melanoma. But these therapies work for only a subset of patients.

23 Jan 2023

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

In a recent study published in The Lancet Microbe journal, researchers described the effectiveness of a modular capsid virus-like coronavirus disease 2019 (COVID-19) vaccination.

22 Jan 2023

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "Single-cell transcriptomics of peripheral blood in the aging mouse."

18 Jan 2023

What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023

CD4 News and Research

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

The nature of the immune responses induced by various COVID-19 vaccines developed using different platforms and formulations

Researchers report a heterologous vaccination strategy against IBV in Chickens

Analysis of rebound virus suggests two separate reservoirs of latent HIV in patients

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Study suggests robust lung mucosal immunity against SARS-CoV-2 can be better achieved through hybrid immunity, as opposed to peripheral vaccination alone

Data demonstrates SARS-CoV-2 Omicron XBB.1.5 substantially escapes NAb responses after bivalent mRNA boosting

Researchers use multiplexed 3D imaging to perform molecular and morphological assessments of colorectal cancers

Dietary plant sugar promotes antitumor immunity and enhances the efficacy of immunotherapy

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

What are the major findings of long COVID research?

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

2022: a year in MIS-C research

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

Researchers analyze targets of human T cell recognition against all coronaviruses

Clinically relevant biomarker strategies in drug development

Research suggests people on rheumatoid arthritis drugs show weaker response to SARS-CoV-2 vaccines

Is universal coronavirus immunity possible?

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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