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Small populations of normal T cells could modify disease severity in patients with XLP1

Human SH2D1A mutations resulting in X-linked lymphoproliferative syndrome type 1 are associated with a unique susceptibility to the Epstein-Barr virus, which may lead to fatal infectious mononucleosis.

9 Nov 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

New approach may lead to protective vaccines for immunocompromised patients

A study led by Som Nanjappa at the University of Illinois College of Veterinary Medicine identifies a cellular target that may improve efficacy in vaccines designed to protect immunocompromised individuals from potentially deadly opportunistic infections.

26 Oct 2018

Gut microbiota could play greater role in pathogenesis of MS than previously thought

In multiple sclerosis, a defective response of the body’s own immune system leads to brain tissue damage. Gastrointestinal microbiota could play a far greater role in the pathogenesis of the disease than previously assumed, researchers at the University of Zurich have now found.

11 Oct 2018

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018

Study shows possibility of using PET imaging to manage chronic liver diseases

While liver biopsies are powerful and reliable, they are also invasive, painful, limited and subject to complications. These effects may soon be a thing of the past for some patients thanks to new research showing PET imaging with the 18F-FAC radiotracer can be used as a non-invasive substitute. The study is featured in the October issue of The Journal of Nuclear Medicine.

5 Oct 2018

Discovery opens door to new therapies for type 1 diabetes

Researchers at St Vincent’s Institute in Melbourne have identified a key target of the immune response that causes type 1 diabetes.

4 Oct 2018

Overlooked immune cells could play a key role in cancer immunotherapy, claims new study

Cancer immunotherapy is a relatively new method of treating cancer and has succeeded with some refractory tumors. However, it doesn’t always work, why not?

21 Sep 2018

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Cancer immunotherapy -- efforts to boost a patient's own immune system, allowing it to better fight cancer cells on its own -- has shown great promise for some previously intractable cancers.

21 Sep 2018

NIH launches clinical trial to test infusions of combination antibodies in people with HIV

A clinical trial testing infusions of combination antibodies in people living with HIV has begun at the National Institutes of Health.

20 Sep 2018

QIAGEN and DiaSorin launch automated, CE-marked workflow for high-throughput TB screening

QIAGEN N.V. and DiaSorin today announced the introduction of an automated, CE-marked workflow for QIAGEN’s QuantiFERON-TB Gold Plus Blood Collection Tubes (QFT-Plus BCT) and a novel DiaSorin LIAISON Test on widely used immunodiagnostic instruments from DiaSorin.

17 Sep 2018

New program combines basic science and social benefits to address HIV risk among young women

A program established by investigators from the Ragon Institute of Massachusetts General Hospital, MIT and Harvard is addressing the persistently elevated risk of HIV infection among young women in South Africa from two angles - first, investigating biological factors that modulate infection risk along with the early immunologic events following viral exposure, and second, alleviating the socioeconomic factors that limit opportunities for young women, the group at greatest risk of infection in the region of the world hardest hit by the HIV epidemic.

17 Sep 2018

Researchers describe mechanism that sets stage for fate decision of T cells

After a pathogen infects the body, the immune system responds with a remarkable -- and remarkably complicated -- cascade of events.

14 Sep 2018

Mouse study suggests new therapeutic approach to treat heart failure

A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death.

10 Sep 2018

Scientists discover key aspect in the development of multiple sclerosis

In multiple sclerosis, not only the T cells of the immune system, but also its B cells, play an important role.

7 Sep 2018

Immune checkpoint inhibition may be effective in treating HIV-associated Kaposi's sarcoma

Among a small cohort of patients with HIV-associated Kaposi's sarcoma treated with immune checkpoint inhibitors, more than 65 percent had partial or complete remission.

7 Sep 2018

Image Cytometry Technology and Tissue Analysis

Image cytometry or tissue cytometry, not only measures the size, diameter and shape of a cell, but quantifies the molecular marker expression.

From TissueGnostics 4 Sep 2018

Researchers discover key aspect in pathogenesis of multiple sclerosis

A team of researchers the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis, it is not only specific T cells that cause inflammation and lesions in the brain.

4 Sep 2018

New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients

In a study, a new HIV drug reduced viral replication and increased immune cells in individuals with advanced, drug-resistant HIV infection. Used in combination with existing HIV medications, the drug is a promising strategy for patients who have run out of effective treatment options, the researchers said.

16 Aug 2018

Researchers find link between common 'harmless' virus and cardiovascular damage

Researchers from Brighton and Sussex Medical School have found an unexpectedly close link between a herpes virus and the occurrence of immune cells damaging cardiovascular tissue.

13 Aug 2018