Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments.
The plot of many a science fiction TV series or movie revolves around the premise that people traveling long distances in space age more slowly than their counterparts on Earth. Now, tiny worms who spent time aboard the International Space Station could help humans understand more about the effects of aging in space for real.
Rooted in malfunctions in the tiny power plants that energize our cells, mitochondrial disorders are notoriously complex and variable, with few effective treatments. Now, novel findings in microscopic worms may hold great promise for children and adults with mitochondrial disorders
A molecular pathway known to suppress tumors appears to also be a major player in clearing cells of damaged proteins implicated in neurodegenerative diseases such as ALS and certain types of dementia, new research in roundworms and human cells suggests.
Virginia Commonwealth University School of Medicine researchers have discovered a biological clue that could help explain why some drinkers develop a dependence on alcohol and others do not.
Even worms have free will. If offered a delicious smell, for example, a roundworm will usually stop its wandering to investigate the source, but sometimes it won't. Just as with humans, the same stimulus does not always provoke the same response, even from the same individual. New research at Rockefeller University, published online today (March 12) in Cell, offers a new neurological explanation for this variability, derived by studying a simple three-cell network within the roundworm brain.
The speed, resolution and sensitivity of the Andor Zyla sCMOS camera has allowed the Vaziri research group in Vienna, Austria, to simultaneously image neuronal activity across an entire organism for the first time.
For more than a century, scientists have understood the basics of inheritance: if good genes help parents survive and reproduce, the parents pass those genes along to their offspring. And yet, recent research has shown that reality is much more complex: genes can be switched off, or silenced, in response to the environment or other factors, and sometimes these changes can be passed from one generation to the next.
A new study identifies three genes that together enable a lethal form of brain cancer to recur and progress after radiation therapy.
A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging.
Four scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a National Institutes of Health Director's New Innovator Award that will forward revolutionary stem cell and neuro-science in medicine.
Imagine being able to take a pill that lets you eat all of the ice cream, cookies, and cakes that you wanted – without gaining any weight.
Through the study of the roundworm, Caenorhabditis elegans, the team led by Hugo Aguilaniu has discovered a hormone that enhances longevity and reduces fertility, thus reproducing the effects of an extreme diet.
When you accidentally touch a hot oven, you rapidly pull your hand away. Although scientists know the basic neural circuits involved in sensing and responding to such painful stimuli, they are still sorting out the molecular players.
An untreatable and deadly neurodegenerative disease has been modelled and treated in worms by University of Liverpool researchers, suggesting a cure could be found for humans.
How nutrients are metabolised and how neurons communicate in the brain are just some of the messages coded by the 3 billion letters that make up the human genome.
Immunity is what stops you dying from a common cold or a tiny pinprick. Differences in resistance or tolerance to disease influence who catches the bug that's going around the office, or which species succumb to the deadly fungus devastating frogs around the world.
A study by Belgian doctoral researcher Wouter De Haes (KU Leuven) and colleagues provides new evidence that metformin, the world's most widely used anti-diabetic drug, slows ageing and increases lifespan.
Researchers at MIT and the University of Vienna have created an imaging system that reveals neural activity throughout the brains of living animals.
Ancient philosophers looked to alchemy for clues to life everlasting. Today, researchers look to their yeast.
Molecular biologists from Indiana University are part of a team that has identified a protein that regulates the information present in a large number of messenger ribonucleic acid molecules that are important for carrying genetic information from DNA to protein synthesis.