Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments.
Thank your mothers: A research collaboration between UC Santa Barbara and L'École Normale Supérieure in Paris has proven that deterministic maternal effects can give offspring a better start on life.
Princeton University researchers have captured among the first recordings of neural activity in nearly the entire brain of a free-moving animal. The three-dimensional recordings could provide scientists with a better understanding of how neurons coordinate action and perception in animals.
Researchers from Princeton University have identified genes important for age-related cognitive declines in memory in adult worm neurons, which had not been studied previously. The research, published in the journal Nature, could eventually point the way toward therapies to extend life and enhance health in aging human populations.
Humans have long sought to reduce the effects of aging. Now, there may be another reason to continue searching for ways to slow the clock--preventing Parkinson's disease.
The Genetics Society of America and the C. elegans research community are pleased to announce the recipients of the GSA poster awards at the 20th International C. elegans Meeting, which took place at the University of California, Los Angeles, June 24-28, 2015.
A team of scientists and engineers at The University of Texas at Austin has identified the first sensor of the Earth's magnetic field in an animal, finding in the brain of a tiny worm a big clue to a long-held mystery about how animals' internal compasses work.
The plot of many a science fiction TV series or movie revolves around the premise that people traveling long distances in space age more slowly than their counterparts on Earth. Now, tiny worms who spent time aboard the International Space Station could help humans understand more about the effects of aging in space for real.
Rooted in malfunctions in the tiny power plants that energize our cells, mitochondrial disorders are notoriously complex and variable, with few effective treatments. Now, novel findings in microscopic worms may hold great promise for children and adults with mitochondrial disorders
A molecular pathway known to suppress tumors appears to also be a major player in clearing cells of damaged proteins implicated in neurodegenerative diseases such as ALS and certain types of dementia, new research in roundworms and human cells suggests.
Virginia Commonwealth University School of Medicine researchers have discovered a biological clue that could help explain why some drinkers develop a dependence on alcohol and others do not.
Even worms have free will. If offered a delicious smell, for example, a roundworm will usually stop its wandering to investigate the source, but sometimes it won't. Just as with humans, the same stimulus does not always provoke the same response, even from the same individual. New research at Rockefeller University, published online today (March 12) in Cell, offers a new neurological explanation for this variability, derived by studying a simple three-cell network within the roundworm brain.
The speed, resolution and sensitivity of the Andor Zyla sCMOS camera has allowed the Vaziri research group in Vienna, Austria, to simultaneously image neuronal activity across an entire organism for the first time.
For more than a century, scientists have understood the basics of inheritance: if good genes help parents survive and reproduce, the parents pass those genes along to their offspring. And yet, recent research has shown that reality is much more complex: genes can be switched off, or silenced, in response to the environment or other factors, and sometimes these changes can be passed from one generation to the next.
A new study identifies three genes that together enable a lethal form of brain cancer to recur and progress after radiation therapy.
A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging.
Four scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a National Institutes of Health Director's New Innovator Award that will forward revolutionary stem cell and neuro-science in medicine.
Imagine being able to take a pill that lets you eat all of the ice cream, cookies, and cakes that you wanted – without gaining any weight.
Through the study of the roundworm, Caenorhabditis elegans, the team led by Hugo Aguilaniu has discovered a hormone that enhances longevity and reduces fertility, thus reproducing the effects of an extreme diet.
When you accidentally touch a hot oven, you rapidly pull your hand away. Although scientists know the basic neural circuits involved in sensing and responding to such painful stimuli, they are still sorting out the molecular players.
An untreatable and deadly neurodegenerative disease has been modelled and treated in worms by University of Liverpool researchers, suggesting a cure could be found for humans.