Capsid News and Research

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Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

T1-spanin breakthrough offers new hope against antibiotic resistance

Given the worldwide prevalence of drug-resistant bacteria, the research fraternity is on the lookout for alternative bactericidal treatment approaches.

12 Mar 2024

HIV virus found to possess hidden transport ability

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

Study reveals how HIV squirms its way into the nucleus during cell invasion

Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it-;inventing all sorts of tricks.

25 Jan 2024

Study reveals new mechanism by which rotavirus induces diarrhea

Rotavirus causes gastroenteritis, a condition that includes diarrhea, deficient nutrient absorption and weight loss. Severe cases result in approximately 128,000 deaths annually in infants and children worldwide.

11 Dec 2023

Empowering oncology research: Transmembrane proteins and cutting-edge production platforms

In this Interview, Dr. Fang-Yi Chu talks to NewsMed about the role of transmembrane proteins in targeting oncology research.

From Sino Biological Inc. 23 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Temperature plays crucial role in virus DNA release and infection

Researchers at Lund University, together with colleagues at the NIST Synchrotron Facility in the USA, have mapped on an atomic level what happens in a virus particle when the temperature is raised.

8 Nov 2023

New gene therapy strategy shows promise for Parkinson's disease

Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and their collaborators have developed a gene therapy strategy to selectively manipulate Parkinson's disease-affected circuitry and attenuate the core motor symptoms of Parkinson's disease in rodent and nonhuman primate animals.

2 Nov 2023

Engineered adeno-associated virus vector yields high transduction of the brain vasculature

Researchers have developed an engineered adeno-associated virus (AAV) vector that yields high transduction of brain vascular pericytes and smooth muscle cells.

24 Aug 2023

DNA origami could be used to create customized virus-like particles

Bioengineers have found a way to program the size and shape of virus particles by combining viral protein building blocks and templates made from DNA.

17 Jul 2023

Griffith University researchers develop new method to control virus assembly

Griffith University researchers have played a key role in using DNA 'origami' templates to control the way viruses are assembled.

17 Jul 2023

Difficult transmembrane protein targets for therapeutic antibodies

In this interview, News-Medical talks to Sylvia Xie, product scientist at Sino Biological, about the ongoing emergence of transmembrane proteins as targets for therapeutic antibodies.

From Sino Biological Inc. 12 Jul 2023

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

UBQLN2 dysfunction in ALS leads to elevated PEG10 levels, suggesting a role for retrotransposon activity in the disease. PEG10's nuclear localization alters gene expression involved in axon remodeling, implicating it as a contributing mechanism in ALS.

7 Jun 2023

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Research presents an assembly-line approach using bacteriophage T4 components to construct artificial viral vectors (AVVs). These AVVs have the potential to revolutionize gene therapies and personalized medicine by enabling the efficient delivery of biomolecules for molecular repairs and genome remodeling.

1 Jun 2023

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Researchers demonstrated the production of cross-clade neutralizing antibodies in response to EV-D68.

19 May 2023

Capsid News and Research

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

T1-spanin breakthrough offers new hope against antibiotic resistance

HIV virus found to possess hidden transport ability

Study reveals how HIV squirms its way into the nucleus during cell invasion

Study reveals new mechanism by which rotavirus induces diarrhea

Empowering oncology research: Transmembrane proteins and cutting-edge production platforms

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Temperature plays crucial role in virus DNA release and infection

New gene therapy strategy shows promise for Parkinson's disease

Engineered adeno-associated virus vector yields high transduction of the brain vasculature

DNA origami could be used to create customized virus-like particles

Griffith University researchers develop new method to control virus assembly

Difficult transmembrane protein targets for therapeutic antibodies

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

Complex assembly process involved in DNA virus replication revealed

Rapid AAV Titer for Bioprocessing in Gene Therapy

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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