Cas9 News and Research

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Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

Prize-winning research offers a promising approach to improve regenerative medicine

Joana Neves is the 2019 grand prize winner of the Sartorius & Science Prize for Regenerative Medicine & Cell Therapy, for work that offers a promising approach to improve the outcome of regenerative stem cell-based therapies aimed at delaying age-related degenerative diseases.

12 Mar 2020

Researchers find way to inactivate cancer protein with the help of another protein

Squamous cell carcinoma is a very unusual type of cancer. They occur in many tissues – for example in the lungs, esophagus, pancreas, throat and pharynx, and on the skin.

10 Mar 2020

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Solute carriers represent the largest family of transmembrane transporters in the human genome, with over 400 members arranged into 65 families.

9 Mar 2020

New genetic tool developed to label specific genes in human organoids

Researchers from the group of Hans Clevers at the Hubrecht Institute have developed a new genetic tool to label specific genes in human organoids, or mini organs.

2 Mar 2020

Gene-editing is more error-prone than thought, new findings suggest

The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences.

26 Feb 2020

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Scientists from Far Eastern Federal University, University of Geneva (Switzerland), Minjiang University, and Fuzhou University (China) pointed out WDR74 protein playing an important role in lung cancer and melanoma primary tumors/metastases progression.

16 Feb 2020

Minigenes produced by CRISPR combat liver disease in mice

A new gene-editing technique based on CRISPR was used to successfully avoid the development of a liver disease that can be caused by hundreds of mutations, as well as to ease the symptoms in mice. This proof-of-concept study was published online in the journal Science Advances in February 2020.

12 Feb 2020

Newly discovered large phages blur the life/non-life boundary

A new study published in the journal Nature shows that there are literally hundreds of viruses large enough to consume bacteria, and with properties that are typical of a living organism rather than the non-living self-replicating packages of DNA/RNA that viruses are often assumed to be.

12 Feb 2020

Pioneering project on genomic edition through CRISPR/Cas9 to study early embryonic development

Characterization studies of early embryonic development are limited, mainly due to the lack of samples and the obvious legal and ethical limitations.

11 Feb 2020

CRISPR-edited immune cells can be safely given to cancer patients

The emergence of CRISPR-Cas9 gene-editing technology has spurred hope in both doctors and patients since it shows promise in treating a multitude of diseases, including cancer. For the first time in the United States, a team of scientists has shown that CRISPR-edited immune cells can be safely used to cancer patients.

9 Feb 2020

Biological toolkit will help researchers design new functions in mammalian cells

A new synthetic biology toolkit developed at Northwestern University will help researchers design mammalian cells with new functionalities.

9 Feb 2020

New gene therapy improves vision in blind mice

Mice born blind have shown significant improvement in vision after undergoing a new gene therapy developed by a team of Japanese scientists.

7 Feb 2020

Coronavirus - pandemic or not?

The coronavirus strain called 2019-nCoV has been causing widespread illness in China, with 28,276 affected by the virus and over 565 deaths worldwide, mostly in China. As of now, it is already more deadly than the SARS epidemic that raged between 2002 and 2004.

6 Feb 2020

Cas9 News and Research

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Prize-winning research offers a promising approach to improve regenerative medicine

Researchers find way to inactivate cancer protein with the help of another protein

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

New genetic tool developed to label specific genes in human organoids

Gene-editing is more error-prone than thought, new findings suggest

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Minigenes produced by CRISPR combat liver disease in mice

Newly discovered large phages blur the life/non-life boundary

Pioneering project on genomic edition through CRISPR/Cas9 to study early embryonic development

CRISPR-edited immune cells can be safely given to cancer patients

Biological toolkit will help researchers design new functions in mammalian cells

New gene therapy improves vision in blind mice

Coronavirus - pandemic or not?

Long noncoding RNA can protect our metabolism against metabolic complications

Gene-editing taken to advanced levels in human stem cells

Death receptor pathway drives resistance to CAR T cell therapy

New gene correction therapy for hereditary muscular disease among children

Drug profiling and gene editing method open new avenues in the development of CAR T-cell therapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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