Cell Development News and Research

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Study demonstrates safety of novel immuno-oncology therapy in patients with advanced solid tumors

A novel therapy designed to help stimulate the body's immune system response against cancer appears to be safe to use as alone or in combination with immune checkpoint inhibitors.

1 Dec 2020

Long-range regulation of tumor suppressor genes plays key role in cancer

Enhancers are regulatory elements that play an important role in cancer.Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, identified a novel enhancer.

25 Nov 2020

Novel mechanism enhances the formation of hematopoietic stem cells

Hematopoietic stem cells can replenish all the different cell types of our blood system. For this reason, hematopoietic stem cells are the cells used in many blood diseases when patients need transplantations.

17 Nov 2020

Flinders University receives funding for new brain cancer research project

The human brain’s biochemistry may be a stumbling block that has been preventing an effective cure for brain cancer.

10 Nov 2020

Polyphenolic compound offers new therapeutic option for chronic inflammatory disorders

Various plants and their products are known to contain "bioactive" ingredients that can alleviate human diseases. These "phytocompounds" often contain restorative biological properties such as anti-cancerous, antioxidant, and anti-inflammatory effects.

24 Sep 2020

Combination of alcohol and nicotine during pregnancy increases health risk in newborns

University of Houston researchers have found that during early pregnancy, the mix of alcohol and nicotine significantly alters the gene regulatory pathways of the developing fetus, which can lead to major deficiencies in brain development.

24 Sep 2020

SUTD scientists use 3D printing to create heart cells from stem cells

All humans start out from a single cell which then divides to eventually form the embryo. Depending on the signals sent by their adjacent cells, these divided cells are then developed or differentiated into specific tissues or organs.

11 Aug 2020

Study: Early training of cell development and network improves response

When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.

7 Aug 2020

Enzyme could play key role in treating cancer, autoimmune diseases in the airway

Findings from a research study, led by scientists at Henry Ford, published in the latest issue of Nature Communications suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in the airway.

5 Aug 2020

New method reveals the dynamics of cell development and gene activity

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only rather than time-lapse films.

4 Aug 2020

Identification of MTK1 SAPKKK as new human oxidative stress sensor

In an aging society, various studies are being conducted to explore the relationship between active oxygen and aging-related diseases such as cancer, chronic inflammatory diseases, and metabolic syndrome.

28 Jul 2020

Researchers investigate the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

UCR postdoctoral researcher receives 'Pathway to Independence' grant from NIH

Rebekah Charney, a postdoctoral researcher in the School of Medicine at the University of California, Riverside, has received a five-year "Pathway to Independence" grant from the National Institute of Dental and Craniofacial Research of the National Institutes of Health, or NIH.

12 Jul 2020

New research can help overcome challenges in diabetes research

Scientists focused on finding better treatments or cures for types 1 or 2 diabetes are painfully aware of current limitations, including having to use animal tissue in studies that often don't translate to human trials.

9 Jul 2020

Novavax SARS-CoV-2 vaccine candidate shows promise in animal models

A new study published on the preprint server bioRxiv in June 2020 shows that a candidate spike protein vaccine can induce neutralizing antibodies, antiviral T cell responses, and protection against infection.

2 Jul 2020

Extended culture of human pancreatic slices as a model to study regeneration of beta cells

Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.

1 Jul 2020

Research team generates comprehensive developmental map of human T-cells

Chintan Parekh, MD, of The Saban Research Institute of Children's Hospital Los Angeles, has led a team of investigators that generated a comprehensive roadmap for how T-cells develop in the human thymus.

16 Jun 2020

New images of LSD1 enzyme in action shed light on gene regulation

New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells--including cancer cells--regulate their genes.

5 Jun 2020

Harmful effects of BPA can be reversed by administering coenzyme Q10

Exposure to bisphenol A (BPA), an industrial chemical used to make certain plastics and resins, inner coatings for food cans and bottle tops, thermal paper used in store receipts, dental sealants and so on, is a concern because of possible adverse health effects, including a reduction in fertility.

7 May 2020

Patients recently recovered from COVID-19 produce virus-specific antibodies

Most newly discharged patients who recently recovered from COVID-19 produce virus-specific antibodies and T cells, suggests a study published on May 3rd in the journal Immunity, but the responses of different patients are not all the same.

5 May 2020