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Chronic exposure to arsenic may increase risk of diabetes, study reveals

A new study reports that chronic exposure to arsenic interferes with insulin secretion in the pancreas, which may increase the risk of diabetes.

10 Jan 2018

Scientists discover mechanism that amplifies autoimmune reaction in early stage islet autoimmunity

Scientists at Helmholtz Zentrum München have discovered a mechanism that amplifies the autoimmune reaction in an early stage of pancreatic islet autoimmunity prior to the progression to clinical type 1 diabetes.

4 Jan 2018

Study opens up new avenues for stopping calcific aortic valve disease

The diminutive size of our aortic valve -- just shy of a quarter -- belies its essential role in pushing oxygen-rich blood from the heart into the aorta, our body's largest vessel, and from there to all other organs. Yet for decades, researchers have focused less on damaged valves than on atherosclerosis, the gradual hardening of the blood vessels themselves.

26 Dec 2017

Two studies show how cells adapt to stressors by reprogramming internal signaling networks

In a pair of publications, researchers have shown how cells adapt to stressors--like water loss--by reprogramming their internal signaling networks.

20 Dec 2017

A woman who can sniff out Parkinson’s disease helps develop diagnostic tests for the disease

Joy Milne is a 67 year old retired nurse from Perth with smelling superpowers. She can smell and detect presence of Parkinson’s disease as has been seen under test conditions. This has led to the understanding of the disease better and helped develop new diagnostic tests to detect Parkinson’s disease early.

18 Dec 2017

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level.

15 Dec 2017

New discovery could speed up production of cells for studying diseases

Scientists have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease.

28 Nov 2017

Newcastle scientists develop new technique that revolutionizes cell culture

A technique which revolutionizes cell culture by allowing the continuous production and collection of cells, has been developed by scientists at Newcastle University.

28 Nov 2017

Diabetes patients’ immune system can regulate insulin production

Inflammation processes are responsible for the failure of insulin production in diabetes patients. The patients' own immune systems can contribute to treatment of this disease: researchers at the University of Basel and University Hospital Basel have found a feedback mechanism that could help maintain insulin production in overweight sufferers, as they report in the journal Immunity.

21 Nov 2017

Common ingredient in laundry detergents may help build bioartificial pancreas to cure type 1 diabetes

Two oxygen-producing compounds – including one that boosts performance in some laundry detergents – might one day play a key role in helping scientists successfully build a bioartificial pancreas in the lab to cure type 1 diabetes.

16 Nov 2017

Scientists uncover mechanism that prevents tumor growth in melanoma

Natural Killer (NK) cells, lymphocytes of the innate immune system with strong cytotoxic activity, play a major role in the immune response against tumors.

8 Nov 2017

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

A popular drug commonly used to treat Alzheimer's disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD).

7 Nov 2017

New research disproves using anti-malaria drug for diabetes treatment

A drug used to treat malaria does not, after all, create new insulin-producing cells, according to a new paper from researchers at the University of California, Davis. The work, published in Cell Metabolism Nov. 2, refutes a study published in Cell in January.

3 Nov 2017

Targeting blood-clotting protein may help treat multiple sclerosis and other diseases

Picture a bare wire, without its regular plastic coating. It's exposed to the elements and risks being degraded. And, without insulation, it may not conduct electricity as well as a coated wire. Now, imagine this wire is inside your brain.

2 Nov 2017

Study demonstrates beneficial effects of calorie-restricted diet in mice

Caloric restriction diets have been associated with various health benefits, but their effects on the skin have not been previously demonstrated. Research conducted at the University of São Paulo (USP) in Brazil shows that controlling calories helps mice live longer, although it reduces the reserves of fat in adipose tissue needed to keep the body warm.

30 Oct 2017

Longevity Biotech receives award to evaluate novel drug candidate for MS in preclinical models

Longevity Biotech, Inc. has received an award from the National Multiple Sclerosis Society through Fast Forward, the Society's commercial research funding program, to evaluate LBT-3627 in preclinical models as a potential disease-modifying therapeutic agent.

28 Oct 2017

Powering up fat cells could help acute myeloid leukemia patients

Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, according to a new study from McMaster University.

16 Oct 2017

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the bone marrow.

22 Sep 2017

Research sheds light on how to improve production of key diabetes cells

Beta cells release insulin in your blood, but when you suffer from Type 1 diabetes, you hardly have any of them left in your body. This is because the immune system attacks the beta cells.

21 Sep 2017

MIT engineers design more effective synthetic mRNA delivery system

By delivering strands of genetic material known as messenger RNA into cells, researchers can induce the cells to produce any protein encoded by the mRNA. This technique holds great potential for administering vaccines or treating diseases such as cancer, but achieving efficient delivery of mRNA has proven challenging.