Central Nervous System News and Research

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Deep brain stimulation to treat Parkinson's makes some act irrationally

An implantable brain device meant to help Parkinson's disease patients better control their movements, has been found to have some worrying side-effects.

29 Oct 2007

Therapeutic gene expression can be sustainable for 1 year

Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans.

28 Oct 2007

Medical College of Wisconsin receives grant to study infantile hemangiomas

The Food and Drug Administration (FDA) has awarded the Medical College of Wisconsin in Milwaukee a three-year, $1 million Orphan Products Development grant to study infantile hemangiomas – a vascular tumor of the skin or internal organs.

25 Oct 2007

Orexigen presents findings on obesity drug candidates

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of central nervous system (CNS) disorders including obesity, has presented the results of a preclinical study that further supports the Company's understanding of an aspect of the mechanism of action of Contrave, one of its two late-stage obesity drug candidates.

24 Oct 2007

West Nile virus' spread through nerve cells linked to serious complication

Scientists believe they have found an explanation for a puzzling and serious complication of West Nile virus infection.

19 Oct 2007

Mayo Clinic clarifies diagnosis for primary central nervous system vasculitis (PCNSV)

Mayo Clinic has clarified the methods of diagnosis and optimal management of a rare and little-understood blood vessel disease of the brain and spinal cord that often leads to stroke or death.

19 Oct 2007

FDA details safe sources for imported puffer fish

The U.S. Food and Drug Administration has released consumer and industry advisories regarding safe sources of puffer fish.

19 Oct 2007

Mental disorders are disorders of the brain

Depression, anxiety disorders such as panic disorder and obsessive-compulsive disorders, alcohol and drug dependence, dementia and Parkinson's disease are just a few examples of "disorders of the brain".

17 Oct 2007

The importance of the endocannabinoid-system

Cannabis (marijuana) is the most widely produced plant-based illicit drug worldwide and the illegal drug most frequently used in Europe.

15 Oct 2007

Familial multiple sclerosis appears more severe than non-familial

Magnetic resonance images (MRI) of a large group of patients with multiple sclerosis has provided the first evidence that those with a history of MS in their families show more severe brain damage than patients who have no close relatives with the disease.

15 Oct 2007

Cigarette smoking may accelerate disability in multiple sclerosis

Persons with multiple sclerosis who smoke risk increasing the amount of brain tissue shrinkage, a consequence of MS, and the subsequent severity of their disease, new research conducted at the Buffalo Neuroimaging Analysis Center (BNAC) at the University at Buffalo has shown.

15 Oct 2007

Antibody repairs myelin in lab study of multiple sclerosis and related disorders

Mayo Clinic researchers have found that a human antibody administered in a single low dose in laboratory mouse models can repair myelin, the insulating covering of nerves that when damaged can lead to multiple sclerosis and other disorders of the central nervous system.

10 Oct 2007

Relatives of patients with Parkinson's disease may have an increased risk of developing dementia

Parkinson's disease is characterized by a decline in the functions of the central nervous system, such as motor skills and speech. Several studies have shown an increased risk of dementia in first-degree relatives of Parkinson's disease patients, while other studies have not confirmed the association, according to background information in the article.

9 Oct 2007

One injection of gene therapy spreads through brain in animal study

By targeting a site in a mouse brain well connected to other areas, researchers successfully delivered a beneficial gene to the entire brain - after one injection of gene therapy.

9 Oct 2007

How does THC work?

Marijuana and its main psychoactive component, THC, exert a plethora of behavioral and autonomic effects on humans and animals.

9 Oct 2007

Central nervous system infections after heart transplants

Central nervous system infections develop infrequently following heart transplants but are a significant predictor of death, according to an article posted online today that will appear in the December 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.

9 Oct 2007