Cerebrovascular Disease News and Research

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Cerebrovascular disease is a group of brain dysfunctions related to disease of the blood vessels supplying the brain. Hypertension is the most important cause; it damages the blood vessel lining, endothelium, exposing the underlying collagen where platelets aggregate to initiate a repairing process which is not always complete and perfect. Sustained hypertension permanently changes the architecture of the blood vessels making them narrow, stiff, deformed, uneven and more vulnerable to fluctuations in blood pressure.

Researchers analyze role of gender in treatment and outcome of patients with MMD

Moyamoya disease is an uncommon, progressive cerebrovascular disease in which the main arteries feeding the brain (the intracranial internal carotid arteries/ICA and Circle of Willis) are narrowed or occluded on both sides, reducing blood flow to the brain. This causes transient episodes of reversible stroke with loss of neurologic function in the form of weakness of a limb, sensory disturbances, epileptic seizures or headaches.

5 May 2010

Liver transplant recipients develop premature immune senescence: Researchers

Researchers at the University of Cambridge found that liver transplant recipients develop premature immune senescence, the normal process by which the immune system ages and becomes less effective. Full details appear in the May issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

30 Apr 2010

Obstructive sleep apnea more than doubles stroke risk in men

Obstructive sleep apnea (OSA) is associated with an increased risk of stroke in middle-aged and older adults, especially men, according to new results from new research supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Overall, sleep apnea more than doubles the risk of stroke in men.

8 Apr 2010

Young adults with hyperthyroidism face increase risk of stroke

Young adults with overactive thyroid face a 44 percent increased risk of stroke compared to those with normal thyroid function, according to a study reported in Stroke: Journal of the American Heart Association.

3 Apr 2010

Proper treatment can help control psoriasis in most cases

For the approximately 7.5 million Americans affected by psoriasis, the thick, red, scaly, itchy plaques it causes only scratch the surface when it comes to the overall implications of this disease. Now, ongoing research linking psoriasis to other serious medical conditions and the incredible toll it can take on a person's overall quality of life are shifting the way psoriasis is viewed - from a common skin disease to a complex systemic condition.

5 Mar 2010

Benefits of aspirin therapy for patients with peripheral artery disease remain unproven

Individuals who were identified as being at increased risk of cardiovascular or cerebrovascular events based on screening for low ankle brachial index, a type of pressure measurement used in the diagnosis of peripheral artery disease, did not significantly reduce their risk of these events with the use of aspirin, according to a study in the March 3 issue of JAMA.

3 Mar 2010

Nearly 40% of TIA and minor ischemic stroke patients may experience mental impairment

Nearly four in 10 transient ischemic attack (TIA) and minor ischemic stroke patients may experience mental impairment, according to a study presented at the American Stroke Association's International Stroke Conference 2010.

25 Feb 2010

High BP may predict dementia in older adults with cognitive impairment

High blood pressure appears to predict the progression to dementia in older adults with impaired executive functions (ability to organize thoughts and make decisions) but not in those with memory dysfunction, according to a report in the February issue of Archives of Neurology, one of the JAMA/Archives journals.

9 Feb 2010

FDA approves sNDA for pediatric autism drug ABILIFY

Bristol-Myers Squibb Company and Otsuka Pharmaceutical Co., Ltd. announced today that the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for ABILIFY® (aripiprazole) for the treatment of irritability associated with autistic disorder in pediatric patients ages 6 to 17 years, including symptoms of aggression towards others, deliberate self-injuriousness, temper tantrums, and quickly changing moods.

20 Nov 2009

Obese patients less likely to achieve cholesterol and blood pressure control

Obese patients taking medications to lower their blood pressure and cholesterol levels are less likely to reach recommended targets for these cardiovascular disease risk factors than their normal weight counterparts, according to new research presented at the 2009 Canadian Cardiovascular Congress hosted by the Canadian Cardiovascular Society and the Heart and Stroke Foundation of Canada.

26 Oct 2009

Vanda Pharmaceuticals announces its agreement with Novartis Pharma AG

Vanda Pharmaceuticals Inc. announced today that it has entered into an agreement with Novartis Pharma AG to commercialize and develop Fanapt(TM) (iloperidone), Vanda's anti-psychotic, in the U.S. and Canada. Fanapt(TM) was approved by the U.S. Food and Drug Administration on May 6, 2009 for the acute treatment of schizophrenia in adults.

14 Oct 2009

Beth Israel Deaconess Medical Center neurologist elected as ANA Honorary Member

Louis R. Caplan, MD, Senior Neurologist at Beth Israel Deaconess Medical Center (BIDMC) and a leader in the treatment and research of strokes, has been elected an Honorary Member of the American Neurological Association (ANA). As the organization's highest honor, Honorary Membership is reserved for select individuals who have made unique contributions to neurology and neurological science throughout their careers.

8 Oct 2009

Rush University receives grants to study how epigenomic changes define cognitive decline

The National Institutes of Health has awarded Rush University Medical Center approximately $5.5 million in grants to study how epigenetic changes - chemical modifications to genes that result from diet, aging, stress, or environmental exposures - define and contribute to memory formation and cognitive decline. Results from the studies could profoundly alter the way the medical community understands, diagnoses, and treats Alzheimer's disease, according to the researchers.

1 Oct 2009

Study on how epigenetic changes contribute to congnitive decline

28 Sep 2009

Final results of SAPHRIS clinical study released

Schering-Plough Corporation today reported final results of a SAPHRIS(R) (asenapine) long-term schizophrenia relapse prevention clinical study.

14 Sep 2009

Newly established Edward Neurosciences Institute to provide advanced stroke care in Chicago

Edward Hospital announced today that it has established the Edward Neurosciences Institute in affiliation with the Northwestern Medical Faculty Foundation to bring the highest level of stroke care in the world to the west and southwest suburbs of Chicago.

11 Sep 2009

The Kyoto Heart study shows positive effect of valsartan on cardiovascular outcome

The KYOTO HEART Study, which took place in Japan between January 2004 and January 2009, shows that the addition of valsartan to conventional antihypertensive treatment to improve blood pressure control is associated with an improved cardiovascular outcome in Japanese hypertensive patients at high risk of CVD events.

2 Sep 2009

Study reveals that valsartan prevents cardiovascular events in high-risk hypertensive Japanese patients

2 Sep 2009

Low level exposure to carbon dioxide leads to increased risk of hospitalization in older people

Exposure to carbon monoxide, even at levels well below national limits, is associated with an increased risk of hospitalization for the elderly with heart problems, according to a study published today in Circulation: Journal of the American Heart Association.

1 Sep 2009

Increased risk of stroke and transient ischemic attack in survivors of Hodgkin lymphoma

Patients treated for Hodgkin lymphoma with radiation therapy have a substantially higher risk of stroke, according to a new study published June 17 online in the Journal of the National Cancer Institute.

17 Jun 2009